CA3134801A1 - Gepotidacine destine a etre utilise dans le traitement d'infections bacteriennes des voies urinaires - Google Patents

Gepotidacine destine a etre utilise dans le traitement d'infections bacteriennes des voies urinaires Download PDF

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Publication number
CA3134801A1
CA3134801A1 CA3134801A CA3134801A CA3134801A1 CA 3134801 A1 CA3134801 A1 CA 3134801A1 CA 3134801 A CA3134801 A CA 3134801A CA 3134801 A CA3134801 A CA 3134801A CA 3134801 A1 CA3134801 A1 CA 3134801A1
Authority
CA
Canada
Prior art keywords
streptococcus
staphylococcus
gepotidacin
uti
resistant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3134801A
Other languages
English (en)
Inventor
David John Payne
Stephen Rittenhouse
Nicole SCANGARELLA-OMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxomithkline Intellectual Property Development Ltd
Original Assignee
Glaxomithkline Intellectual Property Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxomithkline Intellectual Property Development Ltd filed Critical Glaxomithkline Intellectual Property Development Ltd
Publication of CA3134801A1 publication Critical patent/CA3134801A1/fr
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

L'invention concerne des procédés et des composés destinés à être utilisés pour traiter une infection des voies urinaires, comprenant l'administration de gépotidacine ou d'un sel pharmaceutiquement acceptable de celui-ci, dans une quantité thérapeutiquement efficace chez un être humain en ayant besoin, l'infection des voies urinaires étant provoquée par une ou plusieurs bactéries telles que définies dans la description.
CA3134801A 2019-04-03 2020-04-03 Gepotidacine destine a etre utilise dans le traitement d'infections bacteriennes des voies urinaires Pending CA3134801A1 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201962828801P 2019-04-03 2019-04-03
US62/828,801 2019-04-03
US201962834112P 2019-04-15 2019-04-15
US62/834,112 2019-04-15
US201962841384P 2019-05-01 2019-05-01
US201962841363P 2019-05-01 2019-05-01
US201962841375P 2019-05-01 2019-05-01
US62/841,384 2019-05-01
US62/841,363 2019-05-01
US62/841,375 2019-05-01
US201962895601P 2019-09-04 2019-09-04
US201962895594P 2019-09-04 2019-09-04
US201962895590P 2019-09-04 2019-09-04
US62/895,594 2019-09-04
US62/895,601 2019-09-04
US62/895,590 2019-09-04
PCT/IB2020/000261 WO2020201833A1 (fr) 2019-04-03 2020-04-03 Gépotidacine destiné à être utilisé dans le traitement d'infections bactériennes des voies urinaires

Publications (1)

Publication Number Publication Date
CA3134801A1 true CA3134801A1 (fr) 2020-10-08

Family

ID=70861514

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3134801A Pending CA3134801A1 (fr) 2019-04-03 2020-04-03 Gepotidacine destine a etre utilise dans le traitement d'infections bacteriennes des voies urinaires

Country Status (6)

Country Link
EP (1) EP3946342A1 (fr)
JP (2) JP2022528890A (fr)
CN (1) CN114828854A (fr)
BR (1) BR112021018815A2 (fr)
CA (1) CA3134801A1 (fr)
WO (1) WO2020201833A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3210313A1 (fr) 2021-02-05 2022-08-11 Glaxosmithkline Intellectual Property Development Limited Formulations en doses solides administrees par voie orale
CN118574619A (zh) * 2022-01-21 2024-08-30 葛兰素史密斯克莱知识产权发展有限公司 吉泊达星和万古霉素用于治疗由腐生葡萄球菌引起的感染
EP4316463A1 (fr) 2022-08-02 2024-02-07 GlaxoSmithKline Intellectual Property Development Limited Nouvelle formule
JP2025532252A (ja) 2022-09-26 2025-09-29 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド 処置方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001097863A (ja) * 1999-09-24 2001-04-10 Smithkline Beecham Corp 嫌気性病原菌に対するフルオロキノロン化合物の使用法
NZ579877A (en) * 2007-04-20 2011-09-30 Glaxo Group Ltd Tricyclic nitrogen containing compounds as antibacterial agents
CA2958800C (fr) * 2014-08-22 2020-10-27 Glaxosmithkline Intellectual Property Development Limited Composes contenant de l'azote tricyclique pour le traitement de l'infection a neisseria gonorrhoeae

Also Published As

Publication number Publication date
EP3946342A1 (fr) 2022-02-09
WO2020201833A1 (fr) 2020-10-08
JP2025084772A (ja) 2025-06-03
CN114828854A (zh) 2022-07-29
WO2020201833A8 (fr) 2022-08-04
BR112021018815A2 (pt) 2022-03-03
JP2022528890A (ja) 2022-06-16

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