CA3145875C - Conception de polypeptides guidee par apprentissage automatique - Google Patents

Conception de polypeptides guidee par apprentissage automatique

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Publication number
CA3145875C
CA3145875C CA3145875A CA3145875A CA3145875C CA 3145875 C CA3145875 C CA 3145875C CA 3145875 A CA3145875 A CA 3145875A CA 3145875 A CA3145875 A CA 3145875A CA 3145875 C CA3145875 C CA 3145875C
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Canada
Prior art keywords
layers
function
biopolymer
sequence
embedding
Prior art date
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CA3145875A
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English (en)
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CA3145875A1 (fr
Inventor
Jacob D. Feala
Andrew Lane Beam
Molly Krisann Gibson
Bernard Joseph Cabral
Original Assignee
Flagship Pioneering Innovations VI Inc
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Priority claimed from PCT/US2020/044646 external-priority patent/WO2021026037A1/fr
Publication of CA3145875A1 publication Critical patent/CA3145875A1/fr
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Publication of CA3145875C publication Critical patent/CA3145875C/fr
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Anticipated expiration legal-status Critical

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Abstract

L'invention concerne des systèmes, des appareils, un logiciel et des procédés de modification de séquences d'acides aminés conçues pour avoir des fonctions ou des propriétés protéiques spécifiques. L'apprentissage automatique est mis en ?uvre par des procédés de façon à traiter une séquence d'ensemencement d'entrée et à générer, en tant que sortie, une séquence optimisée ayant la fonction ou la propriété souhaitée.
CA3145875A 2019-08-02 2020-07-31 Conception de polypeptides guidee par apprentissage automatique Active CA3145875C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962882150P 2019-08-02 2019-08-02
US201962882159P 2019-08-02 2019-08-02
US62/882,150 2019-08-02
US62/882,159 2019-08-02
PCT/US2020/044646 WO2021026037A1 (fr) 2019-08-02 2020-07-31 Conception de polypeptides guidée par apprentissage automatique

Publications (2)

Publication Number Publication Date
CA3145875A1 CA3145875A1 (fr) 2021-02-11
CA3145875C true CA3145875C (fr) 2026-01-27

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