CA3160508C - Composes de ((((6-benzylamino-5-fluoropyrimidine-4-yl)amino)methyle)-piperidine-1-yl)acetamide substitues actifs a l'endroit des recepteurs nucleaires - Google Patents

Composes de ((((6-benzylamino-5-fluoropyrimidine-4-yl)amino)methyle)-piperidine-1-yl)acetamide substitues actifs a l'endroit des recepteurs nucleaires

Info

Publication number
CA3160508C
CA3160508C CA3160508A CA3160508A CA3160508C CA 3160508 C CA3160508 C CA 3160508C CA 3160508 A CA3160508 A CA 3160508A CA 3160508 A CA3160508 A CA 3160508A CA 3160508 C CA3160508 C CA 3160508C
Authority
CA
Canada
Prior art keywords
amino
methyl
ethyl
din
trifluoromethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3160508A
Other languages
English (en)
Other versions
CA3160508A1 (fr
Inventor
Sanne Schroder Glad
Ian SARVARY
Alex Haahr Gouliaev
Thomas Franch
Soren Jensby Nielsen
Luigi Piero Stasi
Montserrat Erra Sola
Lorena TABOADA MARTINEZ
Joan Taltavull Moll
Juan Francisco Caturla Javaloyes
Lluis Miquel Pages Santacana
Original Assignee
Nuevolution AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuevolution AS filed Critical Nuevolution AS
Priority claimed from PCT/IB2020/062227 external-priority patent/WO2021124279A1/fr
Publication of CA3160508A1 publication Critical patent/CA3160508A1/fr
Application granted granted Critical
Publication of CA3160508C publication Critical patent/CA3160508C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

L'invention concerne des composés de formule (I) actifs vis-à-vis des récepteurs nucléaires, des compositions pharmaceutiques contenant les composés et l'utilisation des composés en thérapie.
CA3160508A 2019-12-20 2020-12-18 Composes de ((((6-benzylamino-5-fluoropyrimidine-4-yl)amino)methyle)-piperidine-1-yl)acetamide substitues actifs a l'endroit des recepteurs nucleaires Active CA3160508C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962951221P 2019-12-20 2019-12-20
US62/951,221 2019-12-20
US202063064502P 2020-08-12 2020-08-12
US63/064,502 2020-08-12
PCT/IB2020/062227 WO2021124279A1 (fr) 2019-12-20 2020-12-18 Composés actifs vis-à-vis des récepteurs nucléaires

Publications (2)

Publication Number Publication Date
CA3160508A1 CA3160508A1 (fr) 2021-06-24
CA3160508C true CA3160508C (fr) 2025-11-04

Family

ID=

Similar Documents

Publication Publication Date Title
US12441704B2 (en) Compounds active towards nuclear receptors
US11447479B2 (en) Compounds active towards nuclear receptors
KR20230017787A (ko) Gpr39 단백질의 길항제
EP4709730A1 (fr) Composés hétéroaryle en tant qu'agents de dégradation dirigés contre un ligand ciblant irak4
CN113214289B (zh) 5-ht2a受体拮抗剂及其治疗中枢神经系统疾病的应用
KR20220146348A (ko) 아데노신 A2a 수용체 길항제로서의 화합물 및 이를 포함하는 약학적 조성물
US11780843B2 (en) Compounds active towards nuclear receptors
US11613532B2 (en) Compounds active towards nuclear receptors
CA3160522C (fr) Composes actifs vis-a-vis des recepteurs nucleaires
EA047629B1 (ru) Соединения, активные в отношении ядерных рецепторов
HK40077526A (en) Compounds active towards nuclear receptors
HK40077526B (en) Compounds active towards nuclear receptors
KR20260010407A (ko) Irak4의 리간드 지정 분해제로서의 헤테로아릴 화합물