CA3176246C - Anticorps anti-tigit - Google Patents

Anticorps anti-tigit

Info

Publication number
CA3176246C
CA3176246C CA3176246A CA3176246A CA3176246C CA 3176246 C CA3176246 C CA 3176246C CA 3176246 A CA3176246 A CA 3176246A CA 3176246 A CA3176246 A CA 3176246A CA 3176246 C CA3176246 C CA 3176246C
Authority
CA
Canada
Prior art keywords
seq
antibody
tigit
antigen
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA3176246A
Other languages
English (en)
Other versions
CA3176246A1 (fr
Inventor
Kelsey Sivick GAUTHIER
Nigel Pelham Clinton Walker
Xiaoning ZHAO
John Lippincott
Original Assignee
Arcus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcus Biosciences Inc filed Critical Arcus Biosciences Inc
Priority claimed from PCT/US2021/035268 external-priority patent/WO2021247591A1/fr
Publication of CA3176246A1 publication Critical patent/CA3176246A1/fr
Application granted granted Critical
Publication of CA3176246C publication Critical patent/CA3176246C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

La présente divulgation concerne des anticorps qui se lient de manière spécifique à TIGIT. Les anticorps ont la capacité d'activation substantielle des lymphocytes T et des cellules tueuses naturelles par inhibition de la liaison de TIGIT au CD155. Les anticorps peuvent être utilisés pour le traitement de cancer et de maladies infectieuses, entre autres.
CA3176246A 2020-06-02 2021-06-01 Anticorps anti-tigit Active CA3176246C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063033609P 2020-06-02 2020-06-02
US63/033,609 2020-06-02
PCT/US2021/035268 WO2021247591A1 (fr) 2020-06-02 2021-06-01 Anticorps anti-tigit

Publications (2)

Publication Number Publication Date
CA3176246A1 CA3176246A1 (fr) 2021-12-09
CA3176246C true CA3176246C (fr) 2026-03-17

Family

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