CA3199475A1 - Procede de conception de vaccin epitopique - Google Patents

Procede de conception de vaccin epitopique

Info

Publication number
CA3199475A1
CA3199475A1 CA3199475A CA3199475A CA3199475A1 CA 3199475 A1 CA3199475 A1 CA 3199475A1 CA 3199475 A CA3199475 A CA 3199475A CA 3199475 A CA3199475 A CA 3199475A CA 3199475 A1 CA3199475 A1 CA 3199475A1
Authority
CA
Canada
Prior art keywords
peptides
mhc
population
optionally
hla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3199475A
Other languages
English (en)
Inventor
Wilfred Jefferies
Paolo Ribeca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
James Hutton Institute
Original Assignee
University of British Columbia
James Hutton Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia, James Hutton Institute filed Critical University of British Columbia
Publication of CA3199475A1 publication Critical patent/CA3199475A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40—Population genetics; Linkage disequilibrium
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Library & Information Science (AREA)
  • Genetics & Genomics (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Software Systems (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioethics (AREA)
  • Public Health (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Ecology (AREA)
  • Physiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un procédé de conception de vaccin épitopique. Le procédé consiste à : a) fournir une ou plusieurs séquences d'acides aminés cibles ; b) éventuellement éliminer des peptides sur la base d'une ou de plusieurs caractéristiques prédéfinies ; c) analyser et sélectionner des peptides de liaison au CMH I et/ou au CMH II à partir desdites séquences ; et d) éventuellement assembler les peptides de liaison au CMH I et/ou au CMH II avec des lieurs pour produire un ensemble de peptides.
CA3199475A 2020-11-24 2021-11-23 Procede de conception de vaccin epitopique Pending CA3199475A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063117496P 2020-11-24 2020-11-24
US63/117,496 2020-11-24
PCT/CA2021/051666 WO2022109726A1 (fr) 2020-11-24 2021-11-23 Procédé de conception de vaccin épitopique

Publications (1)

Publication Number Publication Date
CA3199475A1 true CA3199475A1 (fr) 2022-06-02

Family

ID=81753966

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3199475A Pending CA3199475A1 (fr) 2020-11-24 2021-11-23 Procede de conception de vaccin epitopique

Country Status (4)

Country Link
US (1) US20230402129A1 (fr)
EP (1) EP4252238A4 (fr)
CA (1) CA3199475A1 (fr)
WO (1) WO2022109726A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20260007729A1 (en) * 2022-08-17 2026-01-08 IMMUNEO Therapeutics GmbH Immunization against viral infections disease(s)
LU103078B1 (en) * 2023-02-28 2024-08-28 PMCR GmbH IMMUNIZATION AGAINST CORONAVIRUS
WO2024038157A1 (fr) * 2022-08-17 2024-02-22 PMCR GmbH Immunisation contre le coronavirus

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10676511B2 (en) * 2015-09-17 2020-06-09 Ramot At Tel-Aviv University Ltd. Coronaviruses epitope-based vaccines
GB202004974D0 (en) * 2020-04-03 2020-05-20 Treos Bio Ltd Coronavirus vaccine

Also Published As

Publication number Publication date
EP4252238A4 (fr) 2024-09-25
US20230402129A1 (en) 2023-12-14
WO2022109726A1 (fr) 2022-06-02
EP4252238A1 (fr) 2023-10-04

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