CA3218833A1 - Procedes d'imagerie de detection a distance par photo-absorption (pars) - Google Patents

Procedes d'imagerie de detection a distance par photo-absorption (pars) Download PDF

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Publication number
CA3218833A1
CA3218833A1 CA3218833A CA3218833A CA3218833A1 CA 3218833 A1 CA3218833 A1 CA 3218833A1 CA 3218833 A CA3218833 A CA 3218833A CA 3218833 A CA3218833 A CA 3218833A CA 3218833 A1 CA3218833 A1 CA 3218833A1
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CA
Canada
Prior art keywords
sample
signals
imaging
pars
radiative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3218833A
Other languages
English (en)
Inventor
Parsin Haji Reza
Kevan BELL
Benjamin ECCLESTONE
Vladimir Pekar
Nicholas PELLEGRINO
Paul Fieguth
James Alexander Tummon SIMMONS
James TWEEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Illumisonics Inc
Original Assignee
Illumisonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2021/055380 external-priority patent/WO2021255695A1/fr
Priority claimed from US17/394,919 external-priority patent/US11786128B2/en
Application filed by Illumisonics Inc filed Critical Illumisonics Inc
Publication of CA3218833A1 publication Critical patent/CA3218833A1/fr
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/762—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using clustering, e.g. of similar faces in social networks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Cardiology (AREA)
  • Dispersion Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Multimedia (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Databases & Information Systems (AREA)
  • Computing Systems (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Software Systems (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Light Receiving Elements (AREA)
  • Solid State Image Pick-Up Elements (AREA)

Abstract

L'invention concerne un procédé de visualisation de détails dans un échantillon qui peut consister à générer des signaux radiatifs et non radiatifs dans l'échantillon à un emplacement d'excitation à l'aide d'un faisceau d'excitation, interroger l'échantillon avec un faisceau d'interrogation dirigé vers l'emplacement d'excitation de l'échantillon, et détecter la lumière provenant de l'échantillon. Le faisceau d'excitation peut être focalisé sous une surface de l'échantillon. Le faisceau d'interrogation peut être focalisé sous la surface de l'échantillon. La lumière détectée peut comprendre une partie du faisceau d'interrogation renvoyé de l'échantillon. La lumière détectée peut être indicative des signaux radiatifs et non radiatifs générés.
CA3218833A 2021-05-12 2022-05-12 Procedes d'imagerie de detection a distance par photo-absorption (pars) Pending CA3218833A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US202163187789P 2021-05-12 2021-05-12
US63/187,789 2021-05-12
PCT/IB2021/055380 WO2021255695A1 (fr) 2020-06-18 2021-06-17 Procédés d'imagerie pars
IBPCT/IB2021/055380 2021-06-17
US17/394,919 2021-08-05
US17/394,919 US11786128B2 (en) 2020-06-18 2021-08-05 PARS imaging methods
US202163241170P 2021-09-07 2021-09-07
US63/241,170 2021-09-07
US202263315215P 2022-03-01 2022-03-01
US63/315,215 2022-03-01
PCT/IB2022/054433 WO2022238956A1 (fr) 2021-05-12 2022-05-12 Procédés d'imagerie de détection à distance par photo-absorption (pars)

Publications (1)

Publication Number Publication Date
CA3218833A1 true CA3218833A1 (fr) 2022-11-17

Family

ID=84028417

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3218833A Pending CA3218833A1 (fr) 2021-05-12 2022-05-12 Procedes d'imagerie de detection a distance par photo-absorption (pars)

Country Status (6)

Country Link
EP (1) EP4337934A4 (fr)
JP (1) JP2024518972A (fr)
AU (1) AU2022272873A1 (fr)
CA (1) CA3218833A1 (fr)
IL (1) IL308447A (fr)
WO (1) WO2022238956A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4662479A1 (fr) * 2023-02-08 2025-12-17 Illumisonics Inc. Système de détection à distance d'absorption de photons pour évaluation histologique de tissus
CN116403112B (zh) * 2023-04-11 2023-10-27 生态环境部卫星环境应用中心 农村黑臭水体排查范围划定方法和装置
CN116687350B (zh) * 2023-06-07 2023-11-21 中国医学科学院北京协和医院 利用光谱层析技术实现色素类疾病的边界查找方法
CN116931046B (zh) * 2023-06-14 2025-09-30 四川轻化工大学 一种脉冲信号筛选及信号质量评价方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9999354B2 (en) * 2011-01-21 2018-06-19 National Research Council Of Canada Biological tissue inspection method and system
US10117583B2 (en) * 2014-10-22 2018-11-06 illumiSonics, Inc. Photoacoustic remote sensing (PARS)
JP7028335B2 (ja) * 2018-10-11 2022-03-02 株式会社島津製作所 顕微分光装置、及び顕微分光方法
WO2020222300A1 (fr) * 2019-04-29 2020-11-05 Atonarp Inc. Système optique hybride
CN110823809A (zh) * 2019-12-03 2020-02-21 大连理工大学 一种抗电磁干扰的油中溶解气体原位测量系统及方法
CN111999278B (zh) * 2020-07-13 2023-11-03 北京工业大学 超快时间分辨瞬态反射光、透射光及相关拉曼谱成像系统

Also Published As

Publication number Publication date
EP4337934A4 (fr) 2025-07-23
IL308447A (en) 2024-01-01
EP4337934A1 (fr) 2024-03-20
AU2022272873A1 (en) 2023-11-30
JP2024518972A (ja) 2024-05-08
WO2022238956A1 (fr) 2022-11-17

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