CA975770A - Therapeutically active 2-aminoalkylthio-3h-1.5-benzodiazepines and process for preparing them - Google Patents

Therapeutically active 2-aminoalkylthio-3h-1.5-benzodiazepines and process for preparing them

Info

Publication number
CA975770A
CA975770A CA154,243A CA154243A CA975770A CA 975770 A CA975770 A CA 975770A CA 154243 A CA154243 A CA 154243A CA 975770 A CA975770 A CA 975770A
Authority
CA
Canada
Prior art keywords
aminoalkylthio
benzodiazepines
preparing
therapeutically active
therapeutically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA154,243A
Other languages
English (en)
Other versions
CA154243S (en
Inventor
Dante Nardi
Ludwig Degen
Elena Massarani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT2450972A external-priority patent/IT1045205B/it
Application filed by Recordati SA filed Critical Recordati SA
Application granted granted Critical
Publication of CA975770A publication Critical patent/CA975770A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA154,243A 1971-10-19 1972-10-18 Therapeutically active 2-aminoalkylthio-3h-1.5-benzodiazepines and process for preparing them Expired CA975770A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT3001871 1971-10-19
IT2450972A IT1045205B (it) 1972-05-18 1972-05-18 2 aminoalchiltio 3h i 5 benzodiazepine terapeuticamente attive e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
CA975770A true CA975770A (en) 1975-10-07

Family

ID=26328517

Family Applications (1)

Application Number Title Priority Date Filing Date
CA154,243A Expired CA975770A (en) 1971-10-19 1972-10-18 Therapeutically active 2-aminoalkylthio-3h-1.5-benzodiazepines and process for preparing them

Country Status (15)

Country Link
US (1) US3933793A (fr)
JP (1) JPS5616788B2 (fr)
AT (1) AT321922B (fr)
BE (1) BE790224A (fr)
CA (1) CA975770A (fr)
DE (2) DE2251154C3 (fr)
DK (1) DK143800C (fr)
ES (1) ES407722A1 (fr)
FR (1) FR2157890B1 (fr)
IE (1) IE37514B1 (fr)
IL (1) IL40563A (fr)
NL (1) NL147141B (fr)
NO (1) NO138113C (fr)
SE (1) SE393983B (fr)
YU (1) YU36935B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4123430A (en) * 1977-11-10 1978-10-31 G. D. Searle & Co. 2-Aryl-4-(1-piperazinyl)-3H-1,5-benzodiazepines
JPH0681779U (ja) * 1993-05-11 1994-11-22 エムエイシイサンコー株式会社 状差し
CN112812070B (zh) * 2021-01-30 2022-10-21 陕西师范大学 一种吡啶钯高效催化制备苯二氮卓类化合物的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3296251A (en) * 1963-02-26 1967-01-03 American Home Prod 3-mercapto and 3-substituted mercapto-1, 3-dihydro-2h-1, 4-benzodiazepin-2-ones
DE1933666A1 (de) * 1968-08-17 1970-09-03 Egyt Gyogyszervegyeszeti Gyar Neue 2,3-Dihydro-6,7-benzo-(1,5)-diazepine und Verfahren zur Herstellung derselben
US3595858A (en) * 1969-10-21 1971-07-27 Pfizer 1h-1,5-benzodiazepinecarboxamide antiinflammatory agents
DE2053679A1 (de) * 1970-11-02 1972-05-18 Neue 2-Alkoxy-(bzw. 2-Alkylmercapto)-

Also Published As

Publication number Publication date
AT321922B (de) 1975-04-25
YU249472A (en) 1982-06-18
JPS5616788B2 (fr) 1981-04-18
FR2157890B1 (fr) 1975-10-31
DE2265242A1 (de) 1977-01-13
DE2251154B2 (de) 1980-10-16
NL7214034A (fr) 1973-04-25
US3933793A (en) 1976-01-20
DE2251154C3 (de) 1981-06-25
ES407722A1 (es) 1976-02-16
DE2265242C2 (de) 1983-03-10
DK143800C (da) 1982-03-29
DK143800B (da) 1981-10-12
NO138113C (no) 1978-07-05
NO138113B (no) 1978-03-28
BE790224A (fr) 1973-02-15
IE37514L (en) 1973-04-19
FR2157890A1 (fr) 1973-06-08
IE37514B1 (en) 1977-08-17
IL40563A0 (en) 1972-12-29
NL147141B (nl) 1975-09-15
YU36935B (en) 1984-08-31
JPS4848487A (fr) 1973-07-09
DE2251154A1 (de) 1973-04-26
SE393983B (sv) 1977-05-31
IL40563A (en) 1976-01-30

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