CA982577A - Diamino and dinitro-s-triazines - Google Patents

Diamino and dinitro-s-triazines

Info

Publication number
CA982577A
CA982577A CA117,930A CA117930A CA982577A CA 982577 A CA982577 A CA 982577A CA 117930 A CA117930 A CA 117930A CA 982577 A CA982577 A CA 982577A
Authority
CA
Canada
Prior art keywords
dinitro
triazines
diamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA117,930A
Other languages
English (en)
Other versions
CA117930S (en
Inventor
Roland A.E. Winter
Raymond Seltzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Corp
Original Assignee
Ciba Geigy Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Corp filed Critical Ciba Geigy Corp
Application granted granted Critical
Publication of CA982577A publication Critical patent/CA982577A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/48—Two nitrogen atoms
    • C07D251/52—Two nitrogen atoms with an oxygen or sulfur atom attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA117,930A 1970-07-15 1971-07-12 Diamino and dinitro-s-triazines Expired CA982577A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5524070A 1970-07-15 1970-07-15

Publications (1)

Publication Number Publication Date
CA982577A true CA982577A (en) 1976-01-27

Family

ID=21996600

Family Applications (1)

Application Number Title Priority Date Filing Date
CA117,930A Expired CA982577A (en) 1970-07-15 1971-07-12 Diamino and dinitro-s-triazines

Country Status (8)

Country Link
US (1) US3755322A (fr)
AT (2) AT299965B (fr)
AU (1) AU1826570A (fr)
BE (1) BE754242A (fr)
CA (1) CA982577A (fr)
FR (1) FR2099730A5 (fr)
GB (1) GB1339749A (fr)
NL (1) NL7011392A (fr)

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US3928344A (en) * 1971-12-27 1975-12-23 Degussa Phenylenediamine-s-triazines
IT1060458B (it) * 1975-12-18 1982-08-20 Chimosa Chimica Organica Spa Composti piperidil triazinici adatti per la stabilizzazione di polimeri sintetici e procedimento per la loro preparazione
DE3006803A1 (de) * 1980-02-23 1981-09-03 Bayer Ag, 5090 Leverkusen Vulkanisationsbeschleuniger auf basis von melaminderivaten, melaminderivate enthaltende kautschukmassen sowie ein verfahren zur vulkanisation von kautschuken
DE3401675A1 (de) * 1984-01-19 1985-07-25 Bayer Ag, 5090 Leverkusen Neue polyamine und ein verfahren zu ihrer herstellung
DE3438694A1 (de) * 1984-10-23 1986-04-24 Basf Ag, 6700 Ludwigshafen Neue amidoalkylmelamine und aminoalkylmelamine und verfahren zu ihrer herstellung
EP0945447A1 (fr) * 1998-03-27 1999-09-29 Janssen Pharmaceutica N.V. Dérivés de 1,3,5-triazine trisubstituées pour le traitement de l'infection par le VIH
AU764472B2 (en) * 1998-11-10 2003-08-21 Janssen Pharmaceutica N.V. 2,4-disubstituted triazine derivatives
US6225378B1 (en) * 1999-07-01 2001-05-01 Industrial Technology Research Institute Triazine hardener and epoxy composition containing the same
CA2384188C (fr) * 1999-09-24 2008-06-17 Janssen Pharmaceutica N.V. Compositions antivirales
EP1317450B1 (fr) * 2000-09-15 2006-11-22 Vertex Pharmaceuticals Incorporated Composes de pyrazole utiles comme inhibiteurs de proteine kinase
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US7473691B2 (en) * 2000-09-15 2009-01-06 Vertex Pharmaceuticals Incorporated Pyrazole compounds useful as protein kinase inhibitors
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EP1472245A2 (fr) * 2002-02-06 2004-11-03 Vertex Pharmaceuticals Incorporated Composes heteroaryles utiles en tant qu'inhibiteurs de gsk-3
AU2003218215A1 (en) * 2002-03-15 2003-09-29 Vertex Pharmaceuticals, Inc. Azolylaminoazines as inhibitors of protein kinases
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
DK1532145T3 (da) 2002-08-02 2007-01-15 Vertex Pharma Pyrazolpræparater der er anvendelige som inhibitorer af GSK-3
WO2004072029A2 (fr) * 2003-02-06 2004-08-26 Vertex Pharmaceuticals Incorporated Compositions utiles en tant qu'inhibiteurs de proteine kinases
AU2004297235A1 (en) * 2003-12-04 2005-06-23 Vertex Pharmaceuticals Incorporated Quinoxalines useful as inhibitors of protein kinases
WO2006024175A1 (fr) * 2004-09-03 2006-03-09 Prometic Biosciences Inc. COMPOSÉS À BASE DE 2,4,6-TRIAMINO-S-TRIAZINE RELIÉS À LA PARTIE DE QUEUE (Fc) DES IMMUNOGLOBULINES ET LEUR UTILISATION
ITMI20050222A1 (it) * 2005-02-15 2006-08-16 Milano Politecnico Lipidi cationici per la trasfezione di acidi nucleici
AU2006279376B2 (en) * 2005-08-18 2011-04-14 Vertex Pharmaceuticals Incoporated Pyrazine kinase inhibitors
EP1954277B1 (fr) * 2005-11-03 2017-01-18 Vertex Pharmaceuticals Incorporated Aminopyrimidines utiles en tant qu'inhibiteurs de kinases
MX2009004807A (es) * 2006-11-02 2009-06-15 Vertex Pharma Aminopiridinas y aminopirimidinas utiles como inhibidores de proteina cinasa.
NZ577768A (en) * 2006-12-19 2012-01-12 Vertex Pharma Aminopyrimidines useful as inhibitors of protein kinases
MX2009009590A (es) * 2007-03-09 2009-11-10 Vertex Pharma Aminopirimidinas utiles como inhibidores de proteinas cinasas.
ATE526328T1 (de) * 2007-03-09 2011-10-15 Vertex Pharma Als inhibitoren von proteinkinasen geeignete aminopyrimidine
MX2009009592A (es) * 2007-03-09 2009-11-10 Vertex Pharma Aminopiridinas utiles como inhibidores de proteinas cinasas.
AU2008240313A1 (en) 2007-04-13 2008-10-23 Aj Park Aminopyrimidines useful as kinase inhibitors
AU2008247592A1 (en) 2007-05-02 2008-11-13 Vertex Pharmaceuticals Incorporated Thiazoles and pyrazoles useful as kinase inhibitors
CN101679387A (zh) * 2007-05-02 2010-03-24 沃泰克斯药物股份有限公司 可用作激酶抑制剂的氨基嘧啶类化合物
JP5389786B2 (ja) * 2007-05-02 2014-01-15 バーテックス ファーマシューティカルズ インコーポレイテッド キナーゼ阻害として有用なアミノピリミジン
MX2009012719A (es) * 2007-05-24 2010-02-04 Vertex Pharma Tiazoles y pirazoles utiles como inhibidores de cinasa.
CN101790532B (zh) * 2007-07-31 2013-11-20 沃泰克斯药物股份有限公司 5-氟-1H-吡唑并[3，4-b]吡啶-3-胺及其衍生物的制备方法
WO2010027921A1 (fr) * 2008-09-03 2010-03-11 Vertex Pharmaceuticals Incorporated Co-cristaux et formulations pharmaceutiques les comprenant
AU2010223919B2 (en) 2009-03-13 2016-03-31 Les Laboratoires Servier Methods and compositions for cell-proliferation-related disorders
RU2561132C2 (ru) 2009-06-29 2015-08-20 Аджиос Фармасьютикалз, Инк. Производные хинолинсульфонамидов и их применение для модулирования пкм2 активности
EP3561077B1 (fr) 2009-10-21 2022-12-21 Les Laboratoires Servier Procédés pour des troubles liés à la prolifération cellulaire
SG194697A1 (en) 2011-05-03 2013-12-30 Agios Pharmaceuticals Inc Pyruvate kinase activators for use in therapy
CN102827073A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
CN102827170A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
IN2014MN00381A (fr) * 2011-08-04 2015-06-19 Colourtex Ind Ltd
WO2013024820A1 (fr) * 2011-08-12 2013-02-21 宇部興産株式会社 Précurseur de polyimide, polyimide, film de polyimide et procédé de fabrication d'un composé triazine utilisé pour la fabrication de celui-ci
NZ627096A (en) 2012-01-06 2017-02-24 Agios Pharmaceuticals Inc Triazinyl compounds and their methods of use
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
US9556312B2 (en) * 2012-05-14 2017-01-31 National University Corporation Iwate University Polyimide precursor, polyimide, polyimide film, polyimide metal laminate, and polyimide solution
WO2014062511A1 (fr) 2012-10-15 2014-04-24 Agios Pharmaceuticals, Inc. Composés et compositions thérapeutiques
MY185687A (en) 2013-07-11 2021-05-30 Agios Pharmaceuticals Inc N,6-bis(aryl or heteroaryl)-1,3,5-triazine-2,4-diamine compounds as idh2 mutants inhibitors for the treatment of cancer
WO2015003360A2 (fr) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Composés thérapeutiquement actifs et leurs méthodes d'utilisation
WO2015003355A2 (fr) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Composés thérapeutiquement actifs et leurs méthodes d'utilisation
CN105593215B (zh) 2013-07-11 2019-01-15 安吉奥斯医药品有限公司 用于治疗癌症的作为idh2突变体抑制剂的2,4-或4,6-二氨基嘧啶化合物
CN111087353B (zh) * 2013-07-11 2023-10-24 法国施维雅药厂 治疗活性化合物及其使用方法
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
US20150031627A1 (en) 2013-07-25 2015-01-29 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
KR20240010105A (ko) 2014-03-14 2024-01-23 아지오스 파마슈티컬스 아이엔씨. 치료적으로 활성인 화합물의 약제학적 조성물
FI3307271T3 (fi) 2015-06-11 2023-10-17 Agios Pharmaceuticals Inc Pyruvaattikinaasin aktivaattorien käyttämisen menetelmä
SG11201803088PA (en) 2015-10-15 2018-05-30 Agios Pharmaceuticals Inc Combination therapy for treating malignancies
PT3362066T (pt) 2015-10-15 2021-11-16 Celgene Corp Terapia de combinação para tratar malignidades
CN108640881A (zh) * 2018-04-26 2018-10-12 江汉大学 一种二胺单体及其合成方法
US10980788B2 (en) 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
CN116790213B (zh) * 2023-07-04 2024-02-20 江苏特丽亮新材料科技有限公司 一种耐高温导电胶及其制备方法
CN118652248B (zh) * 2024-05-29 2025-02-14 南京理工大学 6-(4-氨基-1,2,5-噁二唑-3-基)-1,3,5-三嗪-2,4-二胺及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441351A (de) * 1964-06-02 1967-08-15 Geigy Ag J R Verfahren zur Herstellung N2-substituierter 2,4,6-Triamino-1,3,5-triazine
DE1620178A1 (de) * 1965-12-03 1970-03-12 Ruhrchemie Ag Verfahren zur Herstellung von Aminoalkylamino-s-triazinen
US3637685A (en) * 1967-05-15 1972-01-25 Monacelli Walter J Triamino-s-triazines

Also Published As

Publication number Publication date
AT299965B (de) 1972-07-10
AU1826570A (en) 1972-02-03
GB1339749A (en) 1973-12-05
FR2099730A5 (fr) 1972-03-17
AT299216B (de) 1972-06-12
BE754242A (fr) 1971-02-01
US3755322A (en) 1973-08-28
NL7011392A (fr) 1972-01-18

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