CH139636A - Process for the preparation of a condensation product of the benzodiazine series. - Google Patents

Process for the preparation of a condensation product of the benzodiazine series.

Info

Publication number
CH139636A
CH139636A CH139636DA CH139636A CH 139636 A CH139636 A CH 139636A CH 139636D A CH139636D A CH 139636DA CH 139636 A CH139636 A CH 139636A
Authority
CH
Switzerland
Prior art keywords
condensation product
series
preparation
benzodiazine
mol
Prior art date
Application number
Other languages
German (de)
Inventor
Aktiengesellsc Farbenindustrie
Original Assignee
Ig Farbenindustrie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ig Farbenindustrie Ag filed Critical Ig Farbenindustrie Ag
Publication of CH139636A publication Critical patent/CH139636A/en

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

  

  Verfahren zur Darstellung eines Kondensationsproduktes der     Benzodiazinreihe.       Gegenstand     vorliegender    Erfindung ist  ein     Verfahren    zur     Darstellung    eines     Kon-          Uensationsproduktes    der     Benzodiaazinreihe,     dadurch .gekennzeichnet,     @dass    man 1     Mel.        6-          Nitro-2    .

       4-dichlorchinazolin    mit 2     Mol.        1-          Amino-8-ogynaphtalin-3.        6,disulfosäure    kon  densiert.  



  <I>Beispiel:</I>  24,3 Gewichtsteile     6-Nitro-2A-:dIahlor-          chinazo4in,    werden sehr fein     gepulvert    und  gesiebt. Dieses Pulver     trägt    man langsam  ein in eine     ,ganz        schwach        alkalische        Lösung          von    63,8     Gewichtsteilen        1-Amino,-8-ogynaph-          talin-3.6-disulfosäure    in 2000 Teilen Was  ser von 40'.

   Dann     steigert        mann    die Tem  peratur im Verlauf von 2 Stunden auf 80  bis 90  , -wobei man .dauernd gut rührt. Durch       Zusatz    von     Sodalösung    hält     ,man    die     Reak-          tionsmasseeben    neutral.

   Das     Nitroohinazo-          lin    geht     a#lilmählicb.    in Lösung     und:        nach    wei  teren 2     Stunden    ist keine     1-Amina-8-oxy-          naphtaJin.-3.        6,disulfosäure    mehr naichzuwei-         sen.    Jetzt säuert man     .die    Reaktionsmasse  an und gibt etwas Kochsalz     oder    Kalium  chlorid zu.

   Das     Kondensationsprodukt    der  Formel  
EMI0001.0049     
    fällt als gelbe voluminöse Masse, welche sich       in;        Wassser    leicht löst. Diese Lösung fluores  ziert nicht. Nach Ansäuern mit Mineral  säure konnte keine     Nitritaufnahme    festge  stellt werden. Das Kondensationsprodukt      kuppelt mit zwei Molekülen     Diazoniumver-          bindun.gen.  



  Process for the preparation of a condensation product of the benzodiazine series. The present invention relates to a process for the preparation of a con-uensation product of the benzodiaazine series, characterized in that 1 mel. 6- nitro-2.

       4-dichloroquinazoline with 2 moles. 1- amino-8-ogynaphthalene-3. 6, disulfonic acid condenses.



  <I> Example: </I> 24.3 parts by weight 6-Nitro-2A-: dIahlor-chinazo4in, are very finely powdered and sieved. This powder is slowly introduced into a very weakly alkaline solution of 63.8 parts by weight of 1-amino, -8-ogynaphthalene-3.6-disulfonic acid in 2000 parts of water of 40 '.

   Then you increase the temperature in the course of 2 hours to 80 to 90, -which one is constantly stirred well. The addition of soda solution keeps the reaction masses level neutral.

   The Nitroohinazolin goes a # lilmählicb. in solution and: after a further 2 hours there is no 1-Amina-8-oxynaphtaJin.-3. 6, disulfonic acid no longer to be pointed out. Now you acidify the reaction mass and add some table salt or potassium chloride.

   The condensation product of the formula
EMI0001.0049
    falls as a yellow voluminous mass, which is in; Water dissolves easily. This solution does not fluoresce. After acidification with mineral acid, no nitrite uptake could be determined. The condensation product couples with two molecules of diazonium compounds.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung eines Konden sationsproduktes der Benzodiazinreihe von der Formel: EMI0002.0006 dadurch ,gekennzeichnet, @dass man 1 Mol. 6- Nitro-2.4,dichlorcIiinazolin mit 2 Mol. 1- Amino-8-oxynaphta,lin-$. 6-disuilfosäure kon densiert. PATENT CLAIM: Process for the preparation of a condensation product of the benzodiazine series of the formula: EMI0002.0006 characterized in that 1 mol. 6- Nitro-2.4, dichlorociinazoline with 2 mol. 1- Amino-8-oxynaphta, lin- $. 6-disulfonic acid condenses. Das Kondensationsprodukt bildet eine gelbe voluminöse Nasse, die sich in Wasser leicht zu einer nicht fluoreszierenden Lösung löst. Der Körper reagiert mit s,aspetriger iSäure nicht mehr und kuppelt mit 2 Hol. von Diazoniumverbindungen. Es soll als Zwischenprodukt für die Herstellung von Farbstoffen und Arzneimitteln dienen. The condensation product forms a yellow voluminous liquid which easily dissolves in water to form a non-fluorescent solution. The body no longer reacts with aspetriger i-acid and couples with 2 hol. of diazonium compounds. It is intended to serve as an intermediate in the manufacture of dyes and drugs.
CH139636D 1927-03-31 1928-03-20 Process for the preparation of a condensation product of the benzodiazine series. CH139636A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE139636X 1927-03-31
CH133192T 1927-12-12

Publications (1)

Publication Number Publication Date
CH139636A true CH139636A (en) 1930-04-30

Family

ID=25711994

Family Applications (1)

Application Number Title Priority Date Filing Date
CH139636D CH139636A (en) 1927-03-31 1928-03-20 Process for the preparation of a condensation product of the benzodiazine series.

Country Status (1)

Country Link
CH (1) CH139636A (en)

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