CH201177A - Process for the preparation of a 4-oxy-naphthostyril body. - Google Patents
Process for the preparation of a 4-oxy-naphthostyril body.Info
- Publication number
- CH201177A CH201177A CH201177DA CH201177A CH 201177 A CH201177 A CH 201177A CH 201177D A CH201177D A CH 201177DA CH 201177 A CH201177 A CH 201177A
- Authority
- CH
- Switzerland
- Prior art keywords
- naphthostyril
- oxy
- bromo
- methyl
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 4
- 238000002360 preparation method Methods 0.000 title claims description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 229960000583 acetic acid Drugs 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims description 2
- 239000013078 crystal Substances 0.000 claims description 2
- 239000012362 glacial acetic acid Substances 0.000 claims description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 2
- 238000002844 melting Methods 0.000 claims description 2
- 230000008018 melting Effects 0.000 claims description 2
- 239000011707 mineral Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
Verfahren zur Herstellung eines 4-Ogy-naphthostyrilkörpers. Vorliegendes Patent betrifft ein Verfah ren zur Herstellung von N-Methyl-4-ogy-2- brom-naphthostyril, welches dadurch gekenn zeichnet ist, dass man ein mineralsaures Salz von N-Methyl-4-amino-2-brom-naphthostyril in Gegenwart von Wasser auf Temperaturen von 150 bis 200 C erhitzt.
Das so erhaltene neue N-Methyl-4-oxy-2- brom-naphthostyril kristallisiert aus Eisessig in gelben Kristallen vom Schmelzpunkt 308 C und soll zur Darstellung von Farb stoffen und Heilmitteln Verwendung finden. <I>Beispiel:</I> 280 Teile N-Methyl-4-amino-2-brom-naph- thostyril werden mit etwa 2000 Teilen Was ser und 100 Teilen 96 % iger Schwefelsäure vier Stunden auf etwa<B>190'</B> C erhitzt.
Das durch Absaugen des erkalteten Reaktions- produktes abgeschiedene N-Methyl-4-oxy-2- brom-naphthostyrü wird zur Reinigung in. Natronlauge gelöst, filtriert und mit Salz säure gefällt.
Process for making a 4-ogy-naphthostyril body. The present patent relates to a process for the preparation of N-methyl-4-ogy-2-bromo-naphthostyril, which is characterized in that a mineral acid salt of N-methyl-4-amino-2-bromo-naphthostyril is present in the presence heated by water to temperatures of 150 to 200 C.
The new N-methyl-4-oxy-2-bromo-naphthostyril obtained in this way crystallizes from glacial acetic acid in yellow crystals with a melting point of 308 C and is said to be used for the representation of dyes and medicinal products. <I> Example: </I> 280 parts of N-methyl-4-amino-2-bromo-naphthostyril are mixed with about 2000 parts of water and 100 parts of 96% sulfuric acid for four hours to about <B> 190 '< / B> C heated.
The N-methyl-4-oxy-2-bromo-naphthostyrene separated by suction of the cooled reaction product is dissolved in sodium hydroxide solution for purification, filtered and precipitated with hydrochloric acid.
Claims (1)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE201177X | 1935-08-14 | ||
| CH194453T | 1936-08-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH201177A true CH201177A (en) | 1938-11-15 |
Family
ID=25722677
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH201177D CH201177A (en) | 1935-08-14 | 1936-08-07 | Process for the preparation of a 4-oxy-naphthostyril body. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH201177A (en) |
-
1936
- 1936-08-07 CH CH201177D patent/CH201177A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CH201177A (en) | Process for the preparation of a 4-oxy-naphthostyril body. | |
| CH201175A (en) | Process for the preparation of a 4-oxy-naphthostyril body. | |
| CH201174A (en) | Process for the preparation of a 4-oxy-naphthostyril body. | |
| CH201173A (en) | Process for the manufacture of a 4-oxy-naphthostyrill body. | |
| CH201176A (en) | Process for the preparation of a 4-oxy-naphthostyril body. | |
| CH312530A (en) | Process for making a pyridazone. | |
| AT118644B (en) | Process for the preparation of 0,0-diacetyldiphenolisatin. | |
| DE554235C (en) | Process for the preparation of 2,7-dioxynaphthalene-3,6-dicarboxylic acid | |
| DE466360C (en) | Process for the preparation of salts of 1-methyl-4-isopropylbenzenesulfonic acids and their substitution products | |
| CH152474A (en) | Process for the preparation of an oxycarboxylic acid arylide. | |
| CH101402A (en) | Process for the preparation of an aryloxynaphthyl ketone. | |
| CH242291A (en) | Process for the preparation of a p-amino-benzenesulfonamide. | |
| CH184530A (en) | Process for the preparation of a salt of tetrahydro-N-methylnicotinic acid methyl ester. | |
| CH182585A (en) | Process for the preparation of a heterocyclic amino compound. | |
| CH182586A (en) | Process for the preparation of a heterocyclic amino compound. | |
| CH100851A (en) | Process for the preparation of a heterocyclic compound of the naphthalene series. | |
| CH104924A (en) | Process for the production of a thionaphthisatin. | |
| CH161240A (en) | Process for the preparation of the benzoic acid ester of 2-glycolylaminobenzene-1-arsic acid. | |
| CH147681A (en) | Process for the preparation of an aminodiphenylamine derivative. | |
| CH223030A (en) | Process for the production of a condensation product. | |
| CH194997A (en) | Process for the preparation of N- (γ-diethylaminopropyl) -5-amino-m-phenanthroline. | |
| CH145149A (en) | Process for the preparation of the sodium salt of 2-oxo-5-iodopyridine-N-acetic acid. | |
| CH161239A (en) | Process for the preparation of the crotonic acid ester of 2-glycolylaminobenzene-1-arsic acid. | |
| CH191731A (en) | Process for the preparation of a new sulfonic acid. | |
| CH126721A (en) | Process for the preparation of a mixture of 4-chloro- and 6-chloro-5-methylisatin. |