CH201868A - Process for the preparation of a compound of 4-dimethylamino-1-phenyl-2,3-dimethyl-5-pyrazolone which is readily soluble in water. - Google Patents

Process for the preparation of a compound of 4-dimethylamino-1-phenyl-2,3-dimethyl-5-pyrazolone which is readily soluble in water.

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Publication number
CH201868A
CH201868A CH201868DA CH201868A CH 201868 A CH201868 A CH 201868A CH 201868D A CH201868D A CH 201868DA CH 201868 A CH201868 A CH 201868A
Authority
CH
Switzerland
Prior art keywords
sep
water
dimethyl
phenyl
dimethylamino
Prior art date
Application number
Other languages
German (de)
Inventor
Fabriken Knoll A-G Chemische
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of CH201868A publication Critical patent/CH201868A/en

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Description

  

  Verfahren zur Herstellung einer in Wasser leicht löslichen Verbindung des       4-Dimethylamino-l-phenyl-2,3-dimethyl-6-pyrazolons.     
EMI0001.0002     
  
    Gegenstand <SEP> des <SEP> Hauptpatentes <SEP> isst <SEP> ein
<tb>  Verfahren <SEP> zur <SEP> Herstellung <SEP> einer <SEP> in <SEP> Wasser
<tb>  leicht <SEP> löslichen <SEP> Verbindung <SEP> des <SEP> 4-Dimethyl  amino-1-phenyl- <SEP> 2;3 <SEP> -dimethyl-5 <SEP> -pyrazolans.
<tb>  welches <SEP> dadurch <SEP> gekennzeichnet <SEP> ist, <SEP> cass
<tb>  man <SEP> d:iäthylbarbitursaures <SEP> 6-Methylaminoi-2  methyl-2-hepten <SEP> auf <SEP> 4-Dimethylamino-1  phenyl-2"3--dimethyl-,5-pyrazolo#n <SEP> einwirken
<tb>  lässt.
<tb>  



  Nach <SEP> vorliegender <SEP> Ilirfindun;g <SEP> erhält <SEP> man
<tb>  eine <SEP> ebenfalls <SEP> in <SEP> Wasser <SEP> leicht <SEP> lösliche <SEP> Ver  bindung <SEP> des <SEP> 4-Dimethylam-ino-l-phenyl-2:,3  .di#m-ethyl-,5-pyrazolons <SEP> dadurch, <SEP> dass <SEP> man
<tb>  zimtsaures, <SEP> 6--Methylamino-.2-methyl-2-hepten
<tb>  auf <SEP> 4-Dimeth.ylamino-.l-phenyl-2i,3-,d-irnethyl  5-pyrazoloaneinwirken <SEP> lässt.
<tb>  



  Die <SEP> Verbindung <SEP> war <SEP> bisher <SEP> nicht <SEP> be  kannt.. <SEP> Sie <SEP> enthält <SEP> die <SEP> Komponenten <SEP> im
<tb>  molekularen <SEP> Verhältnis <SEP> 1:1 <SEP> und <SEP> ist <SEP> in
<tb>  Wasser <SEP> bei <SEP> Zimmertemperatur <SEP> bis <SEP> zu <SEP> einem
<tb>  Gehalt <SEP> von <SEP> 45 <SEP> % <SEP> klar <SEP> löslich.
<tb>  



  Das <SEP> Verfahren <SEP> wir <SEP> vorteilhaft <SEP> in <SEP> Gegen-     
EMI0001.0003     
  
    wart <SEP> von <SEP> Wasser <SEP> durohgeftihrt, <SEP> und <SEP> zwar
<tb>  derart"dass <SEP> man <SEP> die <SEP> Komponenten <SEP> im <SEP> stöchio  metrischen <SEP> Verhältnis <SEP> 1 <SEP> : <SEP> 1 <SEP> zusammengibt.
<tb>  



  <I>Beispiel:</I>
<tb>  2,8,9 <SEP> .g <SEP> zimtsaures <SEP> 6-Methylamino-2--me  thyl-2-hepten, <SEP> das <SEP> in <SEP> Wasser <SEP> zu <SEP> 3,3% <SEP> löslich
<tb>  ist, <SEP> oder <SEP> anstatt <SEP> dessen <SEP> 14,1 <SEP> g <SEP> 6-Methyl  .amino,2-,methyl-2-hepten <SEP> und <SEP> 14,8 <SEP> :

  g <SEP> 7pim<B><I>-t-</I></B>
<tb>  säure, <SEP> werden <SEP> mit <SEP> 23,1g <SEP> 4-Dimethylamino  1-phenyl-2.,3-,dimethyl-5-pyrazolon <SEP> und <SEP> 68 <SEP> g
<tb>  Wasser <SEP> bis <SEP> zur <SEP> völligen <SEP> Lösung, <SEP> gegebenen  falls <SEP> unter <SEP> Erwärmen <SEP> geschüttelt. <SEP> Die <SEP> klare
<tb>  nahezu <SEP> farblose <SEP> Lösung <SEP> enthält <SEP> 45 <SEP> % <SEP> der <SEP> Ver  bindung <SEP> von <SEP> zimtsaurem <SEP> 6-Metäiylamino-2  methyl <SEP> - <SEP> 2 <SEP> - <SEP> hepten <SEP> mit <SEP> 4- <SEP> Dimethylamino <SEP> -1  phenyl-2"3-dimethyl-5-pyrazolon <SEP> im <SEP> stöchio  metrischen <SEP> Verhältnis <SEP> 1 <SEP> : <SEP> 1.



  Process for the preparation of a compound of 4-dimethylamino-1-phenyl-2,3-dimethyl-6-pyrazolone which is readily soluble in water.
EMI0001.0002
  
    Subject <SEP> of the <SEP> main patent <SEP> is a <SEP>
<tb> Method <SEP> for <SEP> production <SEP> of a <SEP> in <SEP> water
<tb> easily <SEP> soluble <SEP> compound <SEP> of <SEP> 4-dimethylamino-1-phenyl- <SEP> 2; 3 <SEP> -dimethyl-5 <SEP> -pyrazolane.
<tb> which <SEP> is characterized by <SEP> <SEP>, <SEP> cass
<tb> man <SEP> d: iäthylbarbituraures <SEP> 6-methylaminoi-2 methyl-2-heptene <SEP> on <SEP> 4-dimethylamino-1 phenyl-2 "3 - dimethyl-, 5-pyrazolo # n Act on <SEP>
<tb> lets.
<tb>



  After the <SEP> present <SEP> Ilirfindun; g <SEP> one gets <SEP>
<tb> a <SEP> also <SEP> in <SEP> water <SEP> easily <SEP> soluble <SEP> compound <SEP> of <SEP> 4-dimethylamino-l-phenyl-2:, 3 .di # m-ethyl-, 5-pyrazolons <SEP> in that <SEP> that <SEP> man
<tb> cinnamic acid, <SEP> 6 - methylamino-.2-methyl-2-heptene
<tb> on <SEP> lets 4-dimeth.ylamino-.l-phenyl-2i, 3-, d-methyl 5-pyrazoloan act <SEP>.
<tb>



  The <SEP> connection <SEP> was <SEP> previously <SEP> not known <SEP>. <SEP> It <SEP> contains <SEP> the <SEP> components <SEP> in
<tb> molecular <SEP> ratio <SEP> 1: 1 <SEP> and <SEP> is <SEP> in
<tb> water <SEP> at <SEP> room temperature <SEP> to <SEP> to <SEP> one
<tb> Content <SEP> of <SEP> 45 <SEP>% <SEP> clear <SEP> soluble.
<tb>



  The <SEP> procedure <SEP> is <SEP> advantageously <SEP> in <SEP> counterpart
EMI0001.0003
  
    were <SEP> of <SEP> water <SEP> durohetrihrtihrtihrtihrt, <SEP> and <SEP> indeed
<tb> such "that <SEP> one <SEP> combines the <SEP> components <SEP> in the <SEP> stoichio metric <SEP> ratio <SEP> 1 <SEP>: <SEP> 1 <SEP>.
<tb>



  <I> Example: </I>
<tb> 2,8,9 <SEP> .g <SEP> cinnamic acid <SEP> 6-methylamino-2 - methyl-2-heptene, <SEP> the <SEP> in <SEP> water <SEP> <SEP> 3.3% <SEP> soluble
<tb> is, <SEP> or <SEP> instead of <SEP> its <SEP> 14,1 <SEP> g <SEP> 6-methyl .amino, 2-, methyl-2-hepten <SEP> and <SEP > 14.8 <SEP>:

  g <SEP> 7pim <B> <I> -t- </I> </B>
<tb> acid, <SEP> become <SEP> with <SEP> 23.1g <SEP> 4-dimethylamino 1-phenyl-2., 3-, dimethyl-5-pyrazolone <SEP> and <SEP> 68 <SEP > g
<tb> water <SEP> to <SEP> to <SEP> complete <SEP> solution, <SEP> if necessary <SEP> under <SEP> warming <SEP> shaken. <SEP> The <SEP> clear
<tb> almost <SEP> colorless <SEP> solution <SEP> contains <SEP> 45 <SEP>% <SEP> of the <SEP> compound <SEP> of <SEP> cinnamic acid <SEP> 6-metaylamino-2-methyl <SEP> - <SEP> 2 <SEP> - <SEP> hepten <SEP> with <SEP> 4- <SEP> dimethylamino <SEP> -1 phenyl-2 "3-dimethyl-5-pyrazolone <SEP> im < SEP> stoichio metric <SEP> ratio <SEP> 1 <SEP>: <SEP> 1.

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung einer in Wasser leicht löslichen Verbindung des EMI0002.0001 4-Dimethylamino <SEP> -1- <SEP> phenyl- <SEP> \?,3 <SEP> - <SEP> dimethyl <SEP> -5 pyrazolons, <SEP> da=durch <SEP> gekennzeichnet, <SEP> @dass <SEP> man <tb> zimtsaures <SEP> 6-Methylamino-?-methy1-2-hepten <tb> auf <SEP> 4-Dimethyla-mino-l-phen.yl-?,3-dimethyl 5-pyrazolon <SEP> einwirken <SEP> läss.t. <tb> Die <SEP> Verbindung <SEP> enthält <SEP> die <SEP> Komponenten <tb> im <SEP> molekularen <SEP> Verhältnis <SEP> 1 <SEP> : PATENT CLAIM: Process for the production of a compound des that is readily soluble in water EMI0002.0001 4-Dimethylamino <SEP> -1- <SEP> phenyl- <SEP> \ ?, 3 <SEP> - <SEP> dimethyl <SEP> -5 pyrazolons, <SEP> da = marked by <SEP>, <SEP> @that <SEP> man <tb> cinnamic acid <SEP> 6-methylamino -? - methy1-2-hepten <tb> act on <SEP> 4-dimethyla-mino-l-phen.yl - ?, 3-dimethyl 5-pyrazolone <SEP> <SEP> lets.t. <tb> The <SEP> connection <SEP> contains <SEP> the <SEP> components <tb> in the <SEP> molecular <SEP> ratio <SEP> 1 <SEP>: <SEP> 1 <SEP> und <SEP> ist <SEP> in <tb> Wasser <SEP> bei <SEP> Zimmertemperatur <SEP> bis <SEP> zu <SEP> einem <tb> Gehalt <SEP> von <SEP> -15 <SEP> ö <SEP> klar <SEP> Mslich. ÜNTERANSI'RüCHE 1. Verfahren nach Patentanspruch, dadurch gekennzeichnet, dass man die Komponenten in Gegenwart von Wasser aufeinander wirken lässt. <SEP> 1 <SEP> and <SEP> is <SEP> in <tb> water <SEP> at <SEP> room temperature <SEP> to <SEP> to <SEP> one <tb> Salary <SEP> from <SEP> -15 <SEP> ö <SEP> clear <SEP> Mslich. ÜNTERANSI'RüCHE 1. Process according to claim, characterized in that the components are allowed to act on one another in the presence of water. ?. Verfahren nach Patentanspruch, dadurch gekennzeichnet, da3 man die Komponenten im .tüchiametriscben Verhältnis 1 : 1 an wendet.. ?. Method according to patent claim, characterized in that the components are used in a 1: 1 ratio of cloth.
CH201868D 1934-04-27 1935-03-13 Process for the preparation of a compound of 4-dimethylamino-1-phenyl-2,3-dimethyl-5-pyrazolone which is readily soluble in water. CH201868A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201868X 1934-04-27
CH196079T 1935-03-13

Publications (1)

Publication Number Publication Date
CH201868A true CH201868A (en) 1938-12-15

Family

ID=25722824

Family Applications (1)

Application Number Title Priority Date Filing Date
CH201868D CH201868A (en) 1934-04-27 1935-03-13 Process for the preparation of a compound of 4-dimethylamino-1-phenyl-2,3-dimethyl-5-pyrazolone which is readily soluble in water.

Country Status (1)

Country Link
CH (1) CH201868A (en)

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