CH291983A - Process for the production of a furan derivative. - Google Patents

Process for the production of a furan derivative.

Info

Publication number
CH291983A
CH291983A CH291983DA CH291983A CH 291983 A CH291983 A CH 291983A CH 291983D A CH291983D A CH 291983DA CH 291983 A CH291983 A CH 291983A
Authority
CH
Switzerland
Prior art keywords
diacetoxy
production
tetrahydrofuran
chloro
sep
Prior art date
Application number
Other languages
German (de)
Inventor
Ag Sandoz
Original Assignee
Ag Sandoz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ag Sandoz filed Critical Ag Sandoz
Publication of CH291983A publication Critical patent/CH291983A/en

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  • Furan Compounds (AREA)

Description

  

      Verfahren        zur        Herstellung        eines        Furanderivates.       Das vorliegende Patent betrifft ein Ver  fahren zur Herstellung von     2,5-Diaeetoxy-3-          oxy-4-ehlor-tetrahydrofuran,    welches dadurch  gekennzeichnet ist, dass man auf     2,5-Diacetoxy-          2,5-dihydro-furaii    ein     Alkylhypoehlorit    in Eis  essig einwirken lässt, wobei die primär entste  hende     Alkoxy-Gruppe    durch den Eisessig     hy-          drolysiert    wird.  



  <I>Beispiel:</I>  28,7 g     2,5-Diacetoxy-2,5-dihydro-furan    wur  den in 145     em3    Eisessig gelöst und innert    10 Minuten bei etwa 15  C mit 18,1 g     tert.          Butylhypochlorit    versetzt. Das Reaktionsge  misch wurde anschliessend während 14 Minu  ten auf 60  C erwärmt und nach Verlauf  dieser Zeit das Lösungsmittel     abdestilliert.    Der  orange gefärbte Rückstand wurde bei 0,15 mm       Hg    destilliert.

   Man erhielt auf diese 'eise  35,9 g     2,5-Diacetoxy-3-oxy-4-chlor-tetrahydro-          furan,        was        einer        Ausbeute        von        97        %        der     Theorie entspricht.  
EMI0001.0029     
  
    C8H1106C1 <SEP> MG <SEP> : <SEP> 238,5 <SEP> Ber. <SEP> C <SEP> 40,22% <SEP> H <SEP> 4,61%
<tb>  40,40 <SEP> 4,35



      Process for the production of a furan derivative. The present patent relates to a process for the preparation of 2,5-diacetoxy-3-oxy-4-ehlor-tetrahydrofuran, which is characterized in that an alkyl hypoehlorit in 2,5-diacetoxy-2,5-dihydro-furaii Lets glacial vinegar act, whereby the alkoxy group that is primarily formed is hydrolyzed by the glacial acetic acid.



  <I> Example: </I> 28.7 g of 2,5-diacetoxy-2,5-dihydro-furan were dissolved in 145 cubic meters of glacial acetic acid and treated with 18.1 g of tert within 10 minutes at about 15 ° C. Butyl hypochlorite added. The reaction mixture was then heated to 60 ° C. for 14 minutes and after this time the solvent was distilled off. The orange colored residue was distilled at 0.15 mm Hg.

   This gave 35.9 g of 2,5-diacetoxy-3-oxy-4-chloro-tetrahydrofuran, which corresponds to a yield of 97% of theory.
EMI0001.0029
  
    C8H1106C1 <SEP> MG <SEP>: <SEP> 238.5 <SEP> Ber. <SEP> C <SEP> 40.22% <SEP> H <SEP> 4.61%
<tb> 40.40 <SEP> 4.35

 

Claims (1)

PATENTANSPRUCH: Verfahren zur Herstellung von 2,5-Diacet- oxy-3-oxy-4-chlor-tetrahydrofuran, dadurch ge kennzeichnet, dass man auf 2,5-Diacetoxy-2,5- < lilicdro-furan ein Alkylhypochlorit in Eis essig einwirken lässt, wobei die primär entste hende Alkoxy-Gruppe durch den Eisessig hy- drolysIert wird. Die neue Verbindung, das 2,5- Diacetoxy-3-oxy-4-chlor-tetrahydrofuran, de stilliert bei 0,15 mm Druck bei einer Tempera tur von 133 bis 137 und ist ein viskoses, fast farbloses Öl. PATENT CLAIM: Process for the production of 2,5-diacetoxy-3-oxy-4-chloro-tetrahydrofuran, characterized in that an alkyl hypochlorite in glacial acetic acid is used on 2,5-diacetoxy-2,5- <lilicdro-furan can act, whereby the primary alkoxy group is hydrolyzed by the glacial acetic acid. The new compound, the 2,5-diacetoxy-3-oxy-4-chloro-tetrahydrofuran, distilled at 0.15 mm pressure at a temperature of 133 to 137 and is a viscous, almost colorless oil. Das 2,5-Diacetoxy-3-o.Yy-4-chlor-tetrahydro- furan soll als Zwischenprodukt Verwendung finden. The 2,5-diacetoxy-3-o.Yy-4-chloro-tetrahydrofuran is said to be used as an intermediate.
CH291983D 1949-12-02 1949-12-02 Process for the production of a furan derivative. CH291983A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH291983T 1949-12-02
CH283417T 1949-12-02

Publications (1)

Publication Number Publication Date
CH291983A true CH291983A (en) 1953-07-15

Family

ID=25732243

Family Applications (1)

Application Number Title Priority Date Filing Date
CH291983D CH291983A (en) 1949-12-02 1949-12-02 Process for the production of a furan derivative.

Country Status (1)

Country Link
CH (1) CH291983A (en)

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