CH415631A - Verfahren zur Herstellung von a-(3-Indolyl)-niedrigaliphatischen-säuren - Google Patents

Verfahren zur Herstellung von a-(3-Indolyl)-niedrigaliphatischen-säuren

Info

Publication number
CH415631A
CH415631A CH983860A CH983860A CH415631A CH 415631 A CH415631 A CH 415631A CH 983860 A CH983860 A CH 983860A CH 983860 A CH983860 A CH 983860A CH 415631 A CH415631 A CH 415631A
Authority
CH
Switzerland
Prior art keywords
indolyl
acids
preparation
lower aliphatic
aliphatic
Prior art date
Application number
CH983860A
Other languages
German (de)
English (en)
Inventor
Shen Tsung-Ying
Hastings Sarett Lewis
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH415631A publication Critical patent/CH415631A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH983860A 1959-09-03 1960-08-31 Verfahren zur Herstellung von a-(3-Indolyl)-niedrigaliphatischen-säuren CH415631A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83777459A 1959-09-03 1959-09-03

Publications (1)

Publication Number Publication Date
CH415631A true CH415631A (de) 1966-06-30

Family

ID=25275378

Family Applications (1)

Application Number Title Priority Date Filing Date
CH983860A CH415631A (de) 1959-09-03 1960-08-31 Verfahren zur Herstellung von a-(3-Indolyl)-niedrigaliphatischen-säuren

Country Status (5)

Country Link
BE (1) BE594596A (fr)
CH (1) CH415631A (fr)
ES (1) ES260797A1 (fr)
GB (1) GB948460A (fr)
NO (1) NO116545B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB957990A (en) * 1961-03-14 1964-05-13 Merck & Co Inc Salts of substituted indoles
US5081145A (en) * 1990-02-01 1992-01-14 Merck Frosst Canada, Inc. Indole-2-alkanoic acids compositions of and anti allergic use thereof
US5510368A (en) * 1995-05-22 1996-04-23 Merck Frosst Canada, Inc. N-benzyl-3-indoleacetic acids as antiinflammatory drugs

Also Published As

Publication number Publication date
BE594596A (fr) 1961-02-28
ES260797A1 (es) 1961-04-01
NO116545B (fr) 1969-04-14
GB948460A (en) 1964-02-05

Similar Documents

Publication Publication Date Title
CH370197A (de) Verfahren zur Herstellung von Actinospectacin
CH387047A (de) Verfahren zur Herstellung von Ketosidopurinen
CH400144A (de) Verfahren zur Herstellung von 16-Methylen-17a-hydroxy-progesteron-17-acylaten
CH419127A (de) Verfahren zur Herstellung von substituierten 3-Pyrrolidinolen
CH426822A (de) Verfahren zur Herstellung von a-(3-Indolyl)-niederaliphatischen-säuren
CH404962A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH396026A (de) Verfahren zur Herstellung von Halogenalkylaminen
CH415631A (de) Verfahren zur Herstellung von a-(3-Indolyl)-niedrigaliphatischen-säuren
CH387606A (de) Verfahren zur Herstellung von Tetrahydroxydibor
CH399742A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH387029A (de) Verfahren zur Herstellung von 9a-Fluor-11B-oxy-16a-methylprogesteron
CH440249A (de) Verfahren zur Herstellung von Polychlorbenzonitrilen
CH408916A (de) Verfahren zur Herstellung von a-(1-Benzyl-3-indolyl)-niedrig-aliphatischen Säuren
CH417595A (de) Verfahren zur Herstellung von Alkyl-5-alkylisoxazol-3-carboxylaten
CH538458A (de) Verfahren zur Herstellung von a-Dithiosemicarbazonen
CH372297A (de) Verfahren zur Herstellung von 4-2-tert.-Aminomethyl-3-keto-steroiden
CH416113A (de) Verfahren zur Herstellung von Eupolyoxymethylenen
CH395992A (de) Verfahren zur Herstellung von 1-(o-Tolyloxyäthyl)-4-phenyl-piperidin
CH378344A (de) Verfahren zur Herstellung von 2-Amino-anthrachinonen
CH412841A (de) Verfahren zur Herstellung von 2-Trifluormethylbenzophenon
AT221092B (de) Verfahren zur Herstellung von substituierten 2-Oxo-benzochinolizinen
CH385849A (de) Verfahren zur Herstellung von substituierten 2-Oxobenzochinolizinen
AT221096B (de) Verfahren zur Herstellung von 2-Hydrazino-3-mercapto-chinoxalin
AT221103B (de) Verfahren zur Herstellung von Monoalkylphosphinen
AT221494B (de) Verfahren zur Herstellung von α-Amino-ω-lactamen