CH447183A - Verfahren zur Herstellung von neuen Chinazolon-Verbindungen - Google Patents

Verfahren zur Herstellung von neuen Chinazolon-Verbindungen

Info

Publication number: CH447183A
Authority: CH; Switzerland
Prior art keywords: new; production; quinazolone compounds; quinazolone; compounds
Prior art date: 1963-05-18

Application number

CH90567A

Other languages

English (en)

Inventor

Ruschig Heinrich

Hilmer Hans

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1963-05-18

Filing date

1964-05-14

Publication date

1967-11-30

1964-05-14 Application filed by Hoechst Ag filed Critical Hoechst Ag

1967-11-30 Publication of CH447183A publication Critical patent/CH447183A/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

CH90567A 1963-05-18 1964-05-14 Verfahren zur Herstellung von neuen Chinazolon-Verbindungen CH447183A (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DEF39784A DE1231705B (de)	1963-05-18	1963-05-18	Verfahren zur Herstellung von 2, 3-substituierten Chinazolon-(4)-derivaten
DEF0042147		1964-02-28

Publications (1)

Publication Number	Publication Date
CH447183A true CH447183A (de)	1967-11-30

Family

ID=25975761

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CH90467A CH447182A (de)	1963-05-18	1964-05-14	Verfahren zur Herstellung von neuen Chinazolon-Derivaten
CH90567A CH447183A (de)	1963-05-18	1964-05-14	Verfahren zur Herstellung von neuen Chinazolon-Verbindungen
CH628164A CH447181A (de)	1963-05-18	1964-05-14	Verfahren zur Herstellung von Chinazolon-Verbindungen

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
CH90467A CH447182A (de)	1963-05-18	1964-05-14	Verfahren zur Herstellung von neuen Chinazolon-Derivaten

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CH628164A CH447181A (de)	1963-05-18	1964-05-14	Verfahren zur Herstellung von Chinazolon-Verbindungen

Country Status (10)

Country	Link
US (1)	US3322756A (de)
AT (3)	AT258918B (de)
BE (1)	BE648093A (de)
CH (3)	CH447182A (de)
DE (2)	DE1231705B (de)
DK (3)	DK106039C (de)
FR (1)	FR3806M (de)
GB (1)	GB1053063A (de)
NL (1)	NL6405448A (de)
SE (3)	SE314074B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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US3900476A (en) *	1973-05-17	1975-08-19	Upjohn Co	2(2'-pyrimidylamino)quinazolines and their preparation
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US3936453A (en) *	1974-01-28	1976-02-03	Sandoz, Inc.	1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones
US4113637A (en) *	1974-09-10	1978-09-12	Institut Francais Du Petrole	Alkyl-guanidino-heterocyclic compounds, their manufacture and use as additives for fuels and lubricants
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WO1997010221A1 (en) *	1995-09-15	1997-03-20	Torrey Pines Institute For Molecular Studies	Synthesis of quinazolinone libraries
US6258819B1 (en) *	1999-08-05	2001-07-10	Syntex (U.S.A.) Llc	Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
US7671200B2 (en) *	1999-10-27	2010-03-02	Cytokinetics, Inc.	Quinazolinone KSP inhibitors
US7230000B1 (en)	1999-10-27	2007-06-12	Cytokinetics, Incorporated	Methods and compositions utilizing quinazolinones
US6545004B1 (en)	1999-10-27	2003-04-08	Cytokinetics, Inc.	Methods and compositions utilizing quinazolinones
MXPA02010618A (es) *	2000-04-25	2004-05-05	Icos Corp	Inhibidores de fosfatidilinositol 3-quinasa delta.
US6667300B2 (en) *	2000-04-25	2003-12-23	Icos Corporation	Inhibitors of human phosphatidylinositol 3-kinase delta
US20040176361A1 (en) *	2001-05-23	2004-09-09	Masakazu Fujio	Fused heterocyclic compound and medicinal use thereof
EP1444209A4 (de)	2001-11-07	2005-02-16	Merck & Co Inc	Inhibitoren mitotischer kinesine
US6753428B2 (en) *	2001-11-20	2004-06-22	Cytokinetics, Inc.	Process for the racemization of chiral quinazolinones
WO2003070701A2 (en) *	2002-02-15	2003-08-28	Cytokinetics, Inc.	Syntheses of quinazolinones
AU2003270015A1 (en)	2002-05-09	2003-12-02	Cytokinetics, Inc.	Compounds, compositions, and methods
WO2003094839A2 (en) *	2002-05-09	2003-11-20	Cytokinetics, Inc.	Pyrimidinone compounds, compositions and methods
JP2005536475A (ja) *	2002-05-23	2005-12-02	サイトキネティクス・インコーポレーテッド	化合物、組成物、および方法
EP1556357A4 (de) *	2002-06-14	2006-09-13	Cytokinetics Inc	Verbindungen, zusammensetzungen und verfahren
EP1537089A4 (de) *	2002-07-23	2008-04-16	Cytokinetics Inc	Verbindungen, zusammenstellungen und verfahren
AU2003262747A1 (en) *	2002-08-21	2004-03-11	Cytokinetics, Inc.	Compounds, compositions, and methods
EP1558083A4 (de) *	2002-09-30	2008-04-16	Cytokinetics Inc	Verbindungen, zusammensetzungen und verfahren
US20040242568A1 (en)	2003-03-25	2004-12-02	Syrrx, Inc.	Dipeptidyl peptidase inhibitors
EP1506967B1 (de) *	2003-08-13	2007-11-21	Takeda Pharmaceutical Company Limited	Dipeptidyl Peptidase Inhibitoren.
WO2005016349A1 (en) *	2003-08-14	2005-02-24	Icos Corporation	Methods of inhibiting leukocyte accumulation
WO2005016348A1 (en) *	2003-08-14	2005-02-24	Icos Corporation	Method of inhibiting immune responses stimulated by an endogenous factor
EP1699777B1 (de) *	2003-09-08	2012-12-12	Takeda Pharmaceutical Company Limited	Dipeptidylpeptidase-hemmer
JP2007513058A (ja) *	2003-09-08	2007-05-24	武田薬品工業株式会社	ジペプチジルぺプチダーゼ阻害剤
WO2005041888A2 (en) *	2003-11-03	2005-05-12	Cytokinetics, Inc.	Pyrimidin-4-one compounds, compositions and methods
US20050148593A1 (en) *	2003-11-07	2005-07-07	Gustave Bergnes	Compounds, compositions, and methods
JP2007513154A (ja) *	2003-12-08	2007-05-24	サイトキネティクス・インコーポレーテッド	化合物、組成物及び方法
MXPA06010571A (es) *	2004-03-15	2007-02-16	Takeda Pharmaceutical	Inhibidores de dipeptidil peptidasa.
PL1761540T3 (pl)	2004-05-13	2017-06-30	Icos Corporation	Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
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EP1828192B1 (de)	2004-12-21	2014-12-03	Takeda Pharmaceutical Company Limited	Dipeptidylpeptidasehemmer
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DE102005024017A1 (de) *	2005-05-25	2006-11-30	Merck Patent Gmbh	Chinazolinone
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TW200838536A (en) *	2006-11-29	2008-10-01	Takeda Pharmaceutical	Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en)	2007-03-13	2012-01-10	Takeda Pharmaceuticals Company Limited	Weekly administration of dipeptidyl peptidase inhibitors
US9492449B2 (en)	2008-11-13	2016-11-15	Gilead Calistoga Llc	Therapies for hematologic malignancies
NZ631024A (en)	2008-11-13	2016-04-29	Gilead Calistoga Llc	Therapies for hematologic malignancies
SG174529A1 (en)	2009-03-24	2011-10-28	Gilead Calistoga Llc	Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
PT2421536E (pt) *	2009-04-20	2015-10-20	Gilead Calistoga Llc	Métodos de tratamento para tumores sólidos
EP2456443A1 (de)	2009-07-21	2012-05-30	Gilead Calistoga LLC	Behandlung von lebererkrankungen mit pi3k-hemmern
WO2012140642A1 (en)	2011-04-10	2012-10-18	Atir Holding S.A.	Heterocyclic compounds and uses thereof in the treatment of sexual disorders
AP2014007875A0 (en)	2012-03-05	2014-08-31	Gilead Calistoga Llc	Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
EP3083623A1 (de)	2013-12-20	2016-10-26	Gilead Calistoga LLC	Polymorphe formen eines hydrochloridsalzes aus (s)-2-(9h-purin-6-ylamino)propyl)-5-fluor-3-phenylchinazolin-4 (3h)-on
PT3083630T (pt)	2013-12-20	2019-11-15	Gilead Calistoga Llc	Procedimentos para inibidores da fosfatidilinositol 3-quinase
JP6455995B2 (ja)	2014-06-13	2019-01-23	ギリアードサイエンシーズ，インコーポレイテッド	ホスファチジルイノシトール３−キナーゼ阻害剤

0
- GB GB1053063D patent/GB1053063A/en active Active
- DE DENDAT1249281D patent/DE1249281B/de active Pending
1963
- 1963-05-18 DE DEF39784A patent/DE1231705B/de active Pending
1964
- 1964-05-14 US US367568A patent/US3322756A/en not_active Expired - Lifetime
- 1964-05-14 CH CH90467A patent/CH447182A/de unknown
- 1964-05-14 SE SE5933/64A patent/SE314074B/xx unknown
- 1964-05-14 CH CH90567A patent/CH447183A/de unknown
- 1964-05-14 CH CH628164A patent/CH447181A/de unknown
- 1964-05-15 DK DK531164AA patent/DK106039C/da active
- 1964-05-15 AT AT774665A patent/AT258918B/de active
- 1964-05-15 AT AT427764A patent/AT254193B/de active
- 1964-05-15 AT AT774565A patent/AT258917B/de active
- 1964-05-15 DK DK531064AA patent/DK105765C/da active
- 1964-05-15 NL NL6405448A patent/NL6405448A/xx unknown
- 1964-05-15 DK DK245564AA patent/DK104409C/da active
- 1964-05-19 BE BE648093A patent/BE648093A/xx unknown
- 1964-08-17 FR FR985329A patent/FR3806M/fr active Active
1965
- 1965-11-23 SE SE1512665A patent/SE314076B/xx unknown
- 1965-11-23 SE SE1512565A patent/SE314075B/xx unknown

Also Published As

Publication number	Publication date
CH447181A (de)	1967-11-30
NL6405448A (de)	1964-11-19
GB1053063A (de)
CH447182A (de)	1967-11-30
DK105765C (da)	1966-11-07
SE314076B (de)	1969-09-01
AT254193B (de)	1967-05-10
BE648093A (de)	1964-11-19
SE314074B (de)	1969-09-01
DK106039C (da)	1966-12-12
SE314075B (de)	1969-09-01
DE1249281B (de)
AT258917B (de)	1967-12-27
AT258918B (de)	1967-12-27
DK104409C (da)	1966-05-16
FR3806M (fr)	1966-01-03
US3322756A (en)	1967-05-30
DE1231705B (de)	1967-01-05

Publication	Publication Date	Title
AT258918B (de)	1967-12-27	Verfahren zur Herstellung von neuen Chinazolon-Verbindungen
AT261126B (de)	1968-04-10	Verfahren zur Herstellung von neuen Benzomorphanen
CH482648A (de)	1969-12-15	Verfahren zur Herstellung von neuen Phenylzyklopropanverbindungen
AT250942B (de)	1966-12-12	Verfahren zur Herstellung von neuen Sulfonamiden
CH443329A (de)	1967-09-15	Verfahren zur Herstellung von neuen Benzomorphane
CH438319A (de)	1967-06-30	Verfahren zur Herstellung von neuen Azepinderivaten
CH430733A (de)	1967-02-28	Verfahren zur Herstellung von neuen Chinazolinon-Derivaten
AT304077B (de)	1972-12-27	Verfahren zur Herstellung von neuen Esterimidharzen
CH441335A (de)	1967-08-15	Verfahren zur Herstellung von Chinazolin-Derivaten
AT267747B (de)	1969-01-10	Verfahren zur Herstellung von neuen Penicillanylalkoholen
AT248426B (de)	1966-07-25	Verfahren zur Herstellung von neuen Imidazolderivaten
AT249068B (de)	1966-09-26	Verfahren zur Herstellung von neuen Imidazo- und Pyrimido-chinazolinen
AT254184B (de)	1967-05-10	Verfahren zur Herstellung von neuen Äthanoanthracenderivaten
AT242130B (de)	1965-08-25	Verfahren zur Herstellung von neuen Nitrofuryl-Derivaten
AT251591B (de)	1967-01-10	Verfahren zur Herstellung von neuen 4-Nitro-5-hydroxy-pyridazonen-(6)
AT251872B (de)	1967-01-25	Verfahren zur Herstellung von neuen Copolymeren
AT257656B (de)	1967-10-25	Verfahren zur Herstellung von neuen Organophosphoverbindungen
AT241431B (de)	1965-07-26	Verfahren zur Herstellung von neuen Asparaginderivaten
CH419150A (de)	1966-08-31	Verfahren zur Herstellung von neuen Imidazolderivaten
CH490335A (de)	1970-05-15	Verfahren zur Herstellung von neuen Phenylzyklopropanverbindungen
AT270899B (de)	1969-05-12	Verfahren zur Herstellung von neuen Xanthenen
CH429735A (de)	1967-02-15	Verfahren zur Herstellung von neuen Azepinderivaten
CH416643A (de)	1966-07-15	Verfahren zur Herstellung von neuen Azepinderivaten
AT249366B (de)	1966-09-26	Verfahren zur Herstellung von neuen Telomerisaten
AT262504B (de)	1968-06-10	Verfahren zur Herstellung von neuen Penicillinen