CH454887A - Process for the preparation of benzodiazepine derivatives - Google Patents

Process for the preparation of benzodiazepine derivatives

Info

Publication number
CH454887A
CH454887A CH1370566A CH1370566A CH454887A CH 454887 A CH454887 A CH 454887A CH 1370566 A CH1370566 A CH 1370566A CH 1370566 A CH1370566 A CH 1370566A CH 454887 A CH454887 A CH 454887A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH1370566A
Other languages
German (de)
Inventor
A Archer Giles
Ian Fryer Rodney
Reeder Earl
Henryk Sternbach Leo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH454887A publication Critical patent/CH454887A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH1370566A 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives CH454887A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17690162A 1962-03-02 1962-03-02

Publications (1)

Publication Number Publication Date
CH454887A true CH454887A (en) 1968-04-30

Family

ID=22646360

Family Applications (3)

Application Number Title Priority Date Filing Date
CH5067A CH455815A (en) 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives
CH1370566A CH454887A (en) 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives
CH231263A CH438336A (en) 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH5067A CH455815A (en) 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH231263A CH438336A (en) 1962-03-02 1963-02-22 Process for the preparation of benzodiazepine derivatives

Country Status (8)

Country Link
BE (1) BE629005A (en)
BR (1) BR6347108D0 (en)
CH (3) CH455815A (en)
CY (1) CY418A (en)
DE (1) DE1445874A1 (en)
GB (2) GB1040548A (en)
MY (1) MY6800032A (en)
SE (1) SE302127B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218114A (en) * 1991-04-10 1993-06-08 Merck & Co., Inc. Cholecystokinin antagonists
DE19503320A1 (en) * 1995-02-02 1996-08-08 Boehringer Mannheim Gmbh New benzodiazepine conjugates

Also Published As

Publication number Publication date
GB1040547A (en) 1966-09-01
GB1040548A (en) 1966-09-01
DE1445874A1 (en) 1970-07-23
BE629005A (en) 1963-08-28
MY6800032A (en) 1968-12-31
BR6347108D0 (en) 1973-07-19
CY418A (en) 1967-11-30
SE302127B (en) 1968-07-08
CH438336A (en) 1967-06-30
CH455815A (en) 1968-05-15

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