CH461478A - Verfahren zur Herstellung von 5,10-Seco-steroiden - Google Patents

Verfahren zur Herstellung von 5,10-Seco-steroiden

Info

Publication number
CH461478A
CH461478A CH381465A CH381465A CH461478A CH 461478 A CH461478 A CH 461478A CH 381465 A CH381465 A CH 381465A CH 381465 A CH381465 A CH 381465A CH 461478 A CH461478 A CH 461478A
Authority
CH
Switzerland
Prior art keywords
manufacture
seco
steroids
seco steroids
Prior art date
Application number
CH381465A
Other languages
English (en)
Inventor
Georg Dr Anner
Jaroslav Dr Kalvoda
Charles Dr Meystre
Hellmut Dr Ueberwasser
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH878164A priority Critical patent/CH487880A/de
Priority to CH1147564A priority patent/CH505809A/de
Application filed by Ciba Geigy filed Critical Ciba Geigy
Priority to CH381465A priority patent/CH461478A/de
Priority to DE19651518658 priority patent/DE1518658A1/de
Priority to US467691A priority patent/US3431191A/en
Priority to FR22672A priority patent/FR1463849A/fr
Priority to NL6508559A priority patent/NL6508559A/xx
Priority to GB28298/65A priority patent/GB1065432A/en
Publication of CH461478A publication Critical patent/CH461478A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/29—Saturated compounds containing keto groups bound to rings
    • C07C49/313—Saturated compounds containing keto groups bound to rings polycyclic
    • C07C49/323—Saturated compounds containing keto groups bound to rings polycyclic having keto groups bound to condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C07C49/643—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having three rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
CH381465A 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden CH461478A (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden
DE19651518658 DE1518658A1 (de) 1964-07-03 1965-06-26 Neue 5,10-Seco-steroide
US467691A US3431191A (en) 1964-07-03 1965-06-28 Process for producing 5,10-seco-steroids
FR22672A FR1463849A (fr) 1964-07-03 1965-06-29 Nouveaux 5, 10-séco-stéroïdes et procédé pour leur préparation
NL6508559A NL6508559A (de) 1964-07-03 1965-07-02
GB28298/65A GB1065432A (en) 1964-07-03 1965-07-05 New 5,10-seco-steroids and process for their manufacture

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden
CH705165 1965-05-20

Publications (1)

Publication Number Publication Date
CH461478A true CH461478A (de) 1968-08-31

Family

ID=27428676

Family Applications (3)

Application Number Title Priority Date Filing Date
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden
CH381465A CH461478A (de) 1964-07-03 1965-03-18 Verfahren zur Herstellung von 5,10-Seco-steroiden

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CH878164A CH487880A (de) 1964-07-03 1964-07-03 Verfahren zur Herstellung neuer 1(10),5-Oxo 5,10-Secosteroide der Androstan- und Pregnanreihe oder deren 19-nor-Derivate
CH1147564A CH505809A (de) 1964-07-03 1964-09-02 Verfahren zur Herstellung 1(10)-5-oxo-5,10-Seco-steroiden

Country Status (5)

Country Link
US (1) US3431191A (de)
CH (3) CH487880A (de)
DE (1) DE1518658A1 (de)
GB (1) GB1065432A (de)
NL (1) NL6508559A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979458A (en) * 1967-12-04 1976-09-07 Syntex Corporation Production of unsaturated carbocyclic ketones

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662854A (en) * 1950-10-12 1953-12-15 Ciba Pharm Prod Inc Photochemical preparation of 17, 20-hydroxy-ketones of the pregnane series
NL122642C (de) * 1963-02-27

Also Published As

Publication number Publication date
NL6508559A (de) 1966-01-04
GB1065432A (en) 1967-04-12
DE1518658A1 (de) 1969-08-14
CH505809A (de) 1971-04-15
CH487880A (de) 1970-03-31
US3431191A (en) 1969-03-04

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