CH461480A - Verfahren zur Herstellung von 6a, 9a-Difluor-16-methylen-1,4-pregnadien-3,20-dion-11B,17a-diol - Google Patents

Verfahren zur Herstellung von 6a, 9a-Difluor-16-methylen-1,4-pregnadien-3,20-dion-11B,17a-diol

Info

Publication number
CH461480A
CH461480A CH50066A CH50066A CH461480A CH 461480 A CH461480 A CH 461480A CH 50066 A CH50066 A CH 50066A CH 50066 A CH50066 A CH 50066A CH 461480 A CH461480 A CH 461480A
Authority
CH
Switzerland
Prior art keywords
pregnadiene
dione
difluoro
diol
methylene
Prior art date
Application number
CH50066A
Other languages
English (en)
Inventor
Klaus Dr Irmscher
Karl-Heinz Dr Bork
Hans-Guenther Dr Kraft
Original Assignee
Merck Ag E
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Ag E filed Critical Merck Ag E
Publication of CH461480A publication Critical patent/CH461480A/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/843—Corynebacterium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH50066A 1965-03-23 1966-01-14 Verfahren zur Herstellung von 6a, 9a-Difluor-16-methylen-1,4-pregnadien-3,20-dion-11B,17a-diol CH461480A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM0064612 1965-03-23

Publications (1)

Publication Number Publication Date
CH461480A true CH461480A (de) 1968-08-31

Family

ID=7311171

Family Applications (1)

Application Number Title Priority Date Filing Date
CH50066A CH461480A (de) 1965-03-23 1966-01-14 Verfahren zur Herstellung von 6a, 9a-Difluor-16-methylen-1,4-pregnadien-3,20-dion-11B,17a-diol

Country Status (10)

Country Link
US (1) US3396161A (de)
BE (1) BE678137A (de)
BR (1) BR6678034D0 (de)
CH (1) CH461480A (de)
DE (1) DE1251758B (de)
ES (1) ES324499A1 (de)
GB (1) GB1062420A (de)
IL (1) IL25294A (de)
NL (1) NL6602266A (de)
SE (1) SE328282B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS172308B2 (de) * 1968-08-31 1976-12-29
CN103834712B (zh) * 2012-11-26 2016-03-30 复旦大学 去氧孕烯中间体纳米脂质体生物转化的优化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2932639A (en) * 1955-02-02 1960-04-12 Schering Corp Delta1, 4-16, 17-oxido-pregnadienes
US3068224A (en) * 1961-01-09 1962-12-11 Merck & Co Inc 16-alkoxy steroids and processes

Also Published As

Publication number Publication date
US3396161A (en) 1968-08-06
BE678137A (de) 1966-09-21
NL6602266A (de) 1966-09-26
BR6678034D0 (pt) 1973-09-11
IL25294A (en) 1969-11-12
DE1251758B (de) 1967-10-12
ES324499A1 (es) 1967-03-16
GB1062420A (en) 1967-03-22
SE328282B (de) 1970-09-14

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