CH487165A - Verfahren zur Herstellung von Fluorpyrimidinen - Google Patents

Verfahren zur Herstellung von Fluorpyrimidinen

Info

Publication number
CH487165A
CH487165A CH1478667A CH1478667A CH487165A CH 487165 A CH487165 A CH 487165A CH 1478667 A CH1478667 A CH 1478667A CH 1478667 A CH1478667 A CH 1478667A CH 487165 A CH487165 A CH 487165A
Authority
CH
Switzerland
Prior art keywords
fluoropyrimidines
preparation
Prior art date
Application number
CH1478667A
Other languages
English (en)
Inventor
Erich Dr Klauke
Hans-Samuel Dr Bien
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CH487165A publication Critical patent/CH487165A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B62/00Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves
    • C09B62/02Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves with the reactive group directly attached to a heterocyclic ring
    • C09B62/20Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves with the reactive group directly attached to a heterocyclic ring to a pyrimidine ring
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M1/00Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants
    • C10M1/08Liquid compositions essentially based on mineral lubricating oils or fatty oils; Their use as lubricants with additives
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2215/00Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions
    • C10M2215/22Heterocyclic nitrogen compounds
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2215/00Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions
    • C10M2215/22Heterocyclic nitrogen compounds
    • C10M2215/221Six-membered rings containing nitrogen and carbon only
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2215/00Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions
    • C10M2215/22Heterocyclic nitrogen compounds
    • C10M2215/225Heterocyclic nitrogen compounds the rings containing both nitrogen and oxygen
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2215/00Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions
    • C10M2215/22Heterocyclic nitrogen compounds
    • C10M2215/225Heterocyclic nitrogen compounds the rings containing both nitrogen and oxygen
    • C10M2215/226Morpholines
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10MLUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
    • C10M2215/00Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions
    • C10M2215/24Organic non-macromolecular compounds containing nitrogen as ingredients in lubricant Compositions having hydrocarbon substituents containing thirty or more carbon atoms, e.g. nitrogen derivatives of substituted succinic acid
    • C10M2215/30Heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C10PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10NINDEXING SCHEME ASSOCIATED WITH SUBCLASS C10M RELATING TO LUBRICATING COMPOSITIONS
    • C10N2050/00Form in which the lubricant is applied to the material being lubricated
    • C10N2050/015Dispersions of solid lubricants
    • C10N2050/02Dispersions of solid lubricants dissolved or suspended in a carrier which subsequently evaporates to leave a lubricant coating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CH1478667A 1966-12-16 1967-10-23 Verfahren zur Herstellung von Fluorpyrimidinen CH487165A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEF0050972 1966-12-16

Publications (1)

Publication Number Publication Date
CH487165A true CH487165A (de) 1970-03-15

Family

ID=7104227

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1478667A CH487165A (de) 1966-12-16 1967-10-23 Verfahren zur Herstellung von Fluorpyrimidinen

Country Status (6)

Country Link
US (1) US3694444A (de)
BE (1) BE706987A (de)
CH (1) CH487165A (de)
DE (1) DE1670780A1 (de)
GB (1) GB1158300A (de)
NL (1) NL6715443A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2817697A1 (de) * 1978-04-22 1979-10-25 Bayer Ag 2,4-difluor-5-chlor-6-methylpyrimidin und ein verfahren zu seiner herstellung
US4299961A (en) * 1980-01-07 1981-11-10 Pcr, Incorporated 2,4,5 Trifluoro pyrimidine and process for preparing
DE3118700A1 (de) * 1981-05-12 1982-12-02 Bayer Ag, 5090 Leverkusen Im pyrimidinkern monofluorierte seitenkettenhaltige halogenpyrimidine, verfahren zu ihrer herstellung und ihre verwendung bei der herstellung von reaktivfarbstoffen
EP0131543B1 (de) * 1983-06-14 1988-07-13 Ciba-Geigy Ag Reaktivfarbstoffe, deren Herstellung und Verwendung
DE3328154A1 (de) * 1983-08-04 1985-02-21 Bayer Ag, 5090 Leverkusen Neue pyrimidine und ein verfahren zur herstellung von pyrimidinen
DE4222518A1 (de) * 1992-07-09 1994-01-13 Bayer Ag Verfahren zur Hertellung von 5-(Trifluormethyl)-uracil und die neuen Verbindungen 2,4-Dichlor-5-trichlormethyl-pyrimidin und 2,4-Difluor-5-trifluormethyl-pyrimidin
KR100676222B1 (ko) 1999-08-18 2007-01-30 바이엘 악티엔게젤샤프트 4,6-디클로로-5-플루오로피리미딘의 제조방법
US9701635B2 (en) * 2013-07-26 2017-07-11 The Regents Of The University Of California C-H fluorination of heterocycles with silver (II) fluoride
CN104447517B (zh) * 2014-11-19 2017-01-11 上海泰坦科技股份有限公司 用于抗癌类新药研发的高纯氟化试剂的合成工艺

Also Published As

Publication number Publication date
US3694444A (en) 1972-09-26
GB1158300A (en) 1969-07-16
NL6715443A (de) 1968-06-17
BE706987A (de) 1968-05-24
DE1670780A1 (de) 1970-12-23

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Legal Events

Date Code Title Description
PL Patent ceased