CH491886A - Verfahren zur Herstellung eines Pregnadiens - Google Patents

Verfahren zur Herstellung eines Pregnadiens

Info

Publication number: CH491886A
Authority: CH; Switzerland
Prior art keywords: pregnadiene; production
Prior art date: 1960-03-12

Application number

CH871762A

Other languages

English (en)

Inventor

Nagata Wataru

Original Assignee

Shionogi & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1960-03-12

Filing date

1962-07-19

Publication date

1970-06-15

1962-07-19 Application filed by Shionogi & Co filed Critical Shionogi & Co

1970-06-15 Publication of CH491886A publication Critical patent/CH491886A/de

Links

CPUKWYXYHPOQJH-RDQPJNLGSA-N (8r,9s,10s,13s,14s)-17-ethenyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](C)(C(=CC4)C=C)[C@@H]4[C@@H]3CCC21 CPUKWYXYHPOQJH-RDQPJNLGSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
- C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
- C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/44—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with a hydroxy group on a condensed ring system having more than three rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/18—Saturated compounds containing keto groups
- C07C62/26—Saturated compounds containing keto groups containing singly bound oxygen-containing groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/48—Chrysenes; Hydrogenated chrysenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH871762A 1960-03-12 1962-07-19 Verfahren zur Herstellung eines Pregnadiens CH491886A (de)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
JP820860		1960-03-12
JP942160		1960-03-19
JP2012560		1960-04-04
JP2012460		1960-04-04
JP2072360		1960-04-06
JP2241760		1960-04-21
JP2261160		1960-04-25
JP2598661		1961-07-19

Publications (1)

Publication Number	Publication Date
CH491886A true CH491886A (de)	1970-06-15

Family

ID=27571631

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
CH278661A CH416602A (de)	1960-03-12	1961-03-08	Verfahren zur selektiven Einführung einer Cyan-Gruppe in eine Winkelstellung eines Polyhydronaphthalins, Polyhydrophenanthrens, Polyhydrochrysens oder Steroides
CH323761A CH419113A (de)	1960-03-12	1961-03-17	Verfahren zur Herstellung von D-Homo-androstan-18-säuren
CH329266A CH430707A (de)	1960-03-12	1961-03-17	Verfahren zur Herstellung von 18-Oxoverbindungen der 5a- oder 5B-D-Homoandrostan-Reihe bzw. der 19-Nor-1,3,5(10)-pregnatrienreihe
CH377261A CH400138A (de)	1960-03-12	1961-03-29	Verfahren zur Herstellung von 13-Methylverbindungen der 5a- oder 5B-D-Homoandrostan- bzw. der 19-Nor-1,3,5(10)-pregnatrienreihe
CH478061A CH406202A (de)	1960-03-12	1961-04-24	Verfahren zur Herstellung von 3-substituierten D-Homo-18-nor-androst-13-(17a)-en-17-on-derivaten
CH871762A CH491886A (de)	1960-03-12	1962-07-19	Verfahren zur Herstellung eines Pregnadiens

Family Applications Before (5)

Application Number	Title	Priority Date	Filing Date
CH278661A CH416602A (de)	1960-03-12	1961-03-08	Verfahren zur selektiven Einführung einer Cyan-Gruppe in eine Winkelstellung eines Polyhydronaphthalins, Polyhydrophenanthrens, Polyhydrochrysens oder Steroides
CH323761A CH419113A (de)	1960-03-12	1961-03-17	Verfahren zur Herstellung von D-Homo-androstan-18-säuren
CH329266A CH430707A (de)	1960-03-12	1961-03-17	Verfahren zur Herstellung von 18-Oxoverbindungen der 5a- oder 5B-D-Homoandrostan-Reihe bzw. der 19-Nor-1,3,5(10)-pregnatrienreihe
CH377261A CH400138A (de)	1960-03-12	1961-03-29	Verfahren zur Herstellung von 13-Methylverbindungen der 5a- oder 5B-D-Homoandrostan- bzw. der 19-Nor-1,3,5(10)-pregnatrienreihe
CH478061A CH406202A (de)	1960-03-12	1961-04-24	Verfahren zur Herstellung von 3-substituierten D-Homo-18-nor-androst-13-(17a)-en-17-on-derivaten

Country Status (7)

Country	Link
US (4)	US3206472A (de)
CH (6)	CH416602A (de)
DE (5)	DE1234714B (de)
DK (1)	DK113427B (de)
FR (1)	FR1517665A (de)
GB (9)	GB915892A (de)
NL (2)	NL6512737A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL113064C (de) *	1960-03-12
US3294817A (en) *	1964-03-23	1966-12-27	American Home Prod	Octahydroindolobenzazepines and compounds intermediate thereto
US3835160A (en) *	1967-06-06	1974-09-10	Schering Corp	3{40 -keto-2{40 ,3{40 -seco-1{40 -(2{40 )-yne steroidal derivatives, methods for their manufacture, and compounds produced thereby
US3898264A (en) *	1970-08-26	1975-08-05	Hoffmann La Roche	Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
US5028631A (en) *	1987-11-25	1991-07-02	Schwartz Arthur G	Homoandrostan-17-one and homoandrosten-17-ones
US5480913A (en) *	1989-09-27	1996-01-02	Arch Development Corporation	Anti-androgen compounds
US5116865A (en) *	1990-09-05	1992-05-26	Peters Richard H	15,16-seco-19-nor progestins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3024271A (en) *	1958-08-08	1962-03-06	Lab Francais Chimiotherapie	3, 11, 17-trioxygenated-18-nor-d-homo-13alpha-steroids and processes for their preparation
NL113064C (de) *	1960-03-12

0
- NL NL113064D patent/NL113064C/xx active
1961
- 1961-03-08 CH CH278661A patent/CH416602A/de unknown
- 1961-03-09 DE DES72910A patent/DE1234714B/de active Pending
- 1961-03-10 DK DK104661AA patent/DK113427B/da unknown
- 1961-03-10 GB GB8938/61A patent/GB915892A/en not_active Expired
- 1961-03-17 CH CH323761A patent/CH419113A/de unknown
- 1961-03-17 CH CH329266A patent/CH430707A/de unknown
- 1961-03-20 GB GB33717/62A patent/GB959799A/en not_active Expired
- 1961-03-20 DE DES73069A patent/DE1260466B/de active Pending
- 1961-03-20 GB GB10137/61A patent/GB959798A/en not_active Expired
- 1961-03-29 CH CH377261A patent/CH400138A/de unknown
- 1961-03-30 GB GB11848/61A patent/GB945518A/en not_active Expired
- 1961-03-30 DE DES73281A patent/DE1191808B/de active Pending
- 1961-04-24 DE DES73637A patent/DE1172670B/de active Pending
- 1961-04-24 CH CH478061A patent/CH406202A/de unknown
- 1961-04-25 GB GB14975/61A patent/GB936892A/en not_active Expired
- 1961-07-27 US US127097A patent/US3206472A/en not_active Expired - Lifetime
1962
- 1962-07-18 FR FR904344A patent/FR1517665A/fr not_active Expired
- 1962-07-18 US US210842A patent/US3197485A/en not_active Expired - Lifetime
- 1962-07-18 GB GB27669/62A patent/GB984021A/en not_active Expired
- 1962-07-18 GB GB2832/64A patent/GB984023A/en not_active Expired
- 1962-07-18 GB GB2834/64A patent/GB984024A/en not_active Expired
- 1962-07-18 GB GB2830/64A patent/GB984022A/en not_active Expired
- 1962-07-19 DE DES80497A patent/DE1203262B/de active Pending
- 1962-07-19 CH CH871762A patent/CH491886A/de unknown
1965
- 1965-10-01 NL NL6512737A patent/NL6512737A/xx unknown
- 1965-10-19 US US516808A patent/US3407212A/en not_active Expired - Lifetime
- 1965-10-19 US US516807A patent/US3403167A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
GB915892A (en)	1963-01-16
GB936892A (en)	1963-09-18
DK113427B (da)	1969-03-24
DE1234714B (de)	1967-02-23
US3403167A (en)	1968-09-24
CH406202A (de)	1966-01-31
CH416602A (de)	1966-07-15
NL6512737A (de)	1965-12-27
GB984023A (en)	1965-02-24
DE1172670B (de)	1964-06-25
GB984021A (en)	1965-02-24
GB984024A (en)	1965-02-24
CH430707A (de)	1967-02-28
NL113064C (de)
GB945518A (en)	1964-01-02
FR1517665A (fr)	1968-03-22
US3197485A (en)	1965-07-27
US3206472A (en)	1965-09-14
DE1203262B (de)	1965-10-21
DE1260466B (de)	1968-02-08
DE1191808B (de)	1965-04-29
US3407212A (en)	1968-10-22
GB959798A (en)	1964-06-03
CH419113A (de)	1966-08-31
DE1593385A1 (de)	1971-03-25
GB984022A (en)	1965-02-24
CH400138A (de)	1965-10-15
GB959799A (en)	1964-06-03

Publication	Publication Date	Title
CH423789A (de)	1966-11-15	Verfahren zur Herstellung eines Benzimidazols
CH414907A (de)	1966-06-15	Verfahren zur Herstellung eines brikettierten Reinigungsmittels
CH386149A (de)	1964-12-31	Verfahren zur Herstellung eines Reissverschlusses
CH390904A (de)	1965-04-30	Verfahren zur Herstellung von Chlorthiolformaten
CH423019A (de)	1966-10-31	Verfahren zur Herstellung eines umhüllten Supraleiters
CH415632A (de)	1966-06-30	Verfahren zur Herstellung neuer 3-Pyrrolidylmethylamine
CH398149A (de)	1965-08-31	Verfahren zur Herstellung eines Reissverschlusses
CH409892A (de)	1966-03-31	Verfahren zur Herstellung von Peroxo-monosulfaten
CH385813A (de)	1964-12-31	Verfahren zur Herstellung von Dioxyaceton
CH440352A (de)	1967-07-31	Verfahren zur Herstellung eines feinkörnigen Baustahls
CH411353A (de)	1966-04-15	Verfahren zur Herstellung von Polyaldehyden
CH401357A (de)	1965-10-31	Verfahren zur Herstellung von Rufomycin
CH376904A (de)	1964-04-30	Verfahren zur Herstellung von Cyclohexanol
CH397717A (de)	1965-08-31	Verfahren zur Herstellung neuer Monoepoxyde
CH379180A (de)	1964-06-30	Verfahren zur Herstellung eines Reissverschlusses
CH407970A (de)	1966-02-28	Verfahren zur Herstellung neuer Telomerisate
CH390234A (de)	1965-04-15	Verfahren zur Herstellung von Vinylthioäthylthiolphosph3r- bzw, -phosphonsäureestern
AT231203B (de)	1964-01-27	Verfahren zur Herstellung eines Schmuckgegenstandes
CH407979A (de)	1966-02-28	Verfahren zur Herstellung neuer antidiabetisch wirksamer Benzolsulfonylharnstoffe
AT241029B (de)	1965-06-25	Verfahren zur Herstellung eines Desinfektionsmittels
CH397672A (de)	1965-08-31	Verfahren zur Herstellung von Tetraorganodiphosphinen
CH407072A (de)	1966-02-15	Verfahren zur Herstellung neuer Telomerisate
CH411671A (de)	1966-04-15	Verfahren zur Herstellung eines Beton-Kies-Ersatzes
CH404670A (de)	1965-12-31	Verfahren zur Herstellung von w-Lactamen
CH397674A (de)	1965-08-31	Verfahren zur Herstellung von Dialkoxyvinylboran