CH498805A - Verfahren zur Herstellung von Cystinrest-haltigen Peptiden - Google Patents

Verfahren zur Herstellung von Cystinrest-haltigen Peptiden

Info

Publication number
CH498805A
CH498805A CH699968A CH699968A CH498805A CH 498805 A CH498805 A CH 498805A CH 699968 A CH699968 A CH 699968A CH 699968 A CH699968 A CH 699968A CH 498805 A CH498805 A CH 498805A
Authority
CH
Switzerland
Prior art keywords
solution
cys
tri
tbu
mmol
Prior art date
Application number
CH699968A
Other languages
German (de)
English (en)
Inventor
Bruno Dr Kamber
Werner Dr Rittel
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Priority to CH699968A priority Critical patent/CH498805A/de
Priority to DE19681806135 priority patent/DE1806135A1/de
Priority to DE19681817938 priority patent/DE1817938A1/de
Priority to IL30992A priority patent/IL30992A0/xx
Priority to GB52391/68A priority patent/GB1243035A/en
Priority to CA034,471A priority patent/CA992958A/en
Priority to NO443468A priority patent/NO124537B/no
Priority to FR1593126D priority patent/FR1593126A/fr
Priority to BE723588D priority patent/BE723588A/xx
Priority to NL6815962A priority patent/NL6815962A/xx
Priority to JP43081822A priority patent/JPS4810480B1/ja
Priority to OA53421A priority patent/OA03377A/xx
Priority to FR6912962A priority patent/FR2008194A1/fr
Priority to YU105469A priority patent/YU35343B/xx
Priority to GB1259017D priority patent/GB1259017A/en
Priority to DE1922562A priority patent/DE1922562C3/de
Priority to CS3270*BA priority patent/CS150978B2/cs
Priority to PL13344469A priority patent/PL88876B1/pl
Priority to DK254069AA priority patent/DK126990B/da
Priority to NL6907160.A priority patent/NL165149B/xx
Priority to BE732851D priority patent/BE732851A/xx
Publication of CH498805A publication Critical patent/CH498805A/de
Priority to JP4261571A priority patent/JPS4811720B1/ja
Priority to US05/206,933 priority patent/US3956260A/en
Priority to US05/685,857 priority patent/US4271068A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/067—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for sulfur-containing functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CH699968A 1967-11-09 1968-05-10 Verfahren zur Herstellung von Cystinrest-haltigen Peptiden CH498805A (de)

Priority Applications (24)

Application Number Priority Date Filing Date Title
CH699968A CH498805A (de) 1968-05-10 1968-05-10 Verfahren zur Herstellung von Cystinrest-haltigen Peptiden
DE19681806135 DE1806135A1 (de) 1967-11-09 1968-10-30 Neue hypocalcaemische Peptide und Verfahren zu ihrer Herstellung
DE19681817938 DE1817938A1 (de) 1967-11-09 1968-10-30 Neue hypocalcaemische peptide und verfahren zu ihrer herstellung
IL30992A IL30992A0 (en) 1967-11-09 1968-11-01 New hypocalcaemic peptides and processes for their manufacture
GB52391/68A GB1243035A (en) 1967-11-09 1968-11-05 New hypocalcaemic peptides and processes for their manufacture
CA034,471A CA992958A (en) 1967-11-09 1968-11-06 Hypocalcaemic peptides and processes for their manufacture
NO443468A NO124537B (cs) 1967-11-09 1968-11-07
FR1593126D FR1593126A (cs) 1967-11-09 1968-11-07
BE723588D BE723588A (cs) 1967-11-09 1968-11-08
NL6815962A NL6815962A (cs) 1967-11-09 1968-11-08
JP43081822A JPS4810480B1 (cs) 1967-11-09 1968-11-09
OA53421A OA03377A (fr) 1968-02-06 1968-11-11 Procédé pour la préparation de nouveaux peptides hypo-calcémiants.
FR6912962A FR2008194A1 (cs) 1968-05-10 1969-04-24
YU105469A YU35343B (en) 1968-05-10 1969-04-29 Process for obtaining cystine containing peptides
GB1259017D GB1259017A (cs) 1968-05-10 1969-04-30
DE1922562A DE1922562C3 (de) 1968-05-10 1969-05-02 Verfahren zur Herstellung von Cystinhaltigen Peptiden
CS3270*BA CS150978B2 (cs) 1968-05-10 1969-05-08
DK254069AA DK126990B (da) 1968-05-10 1969-05-09 Fremgangsmåde til fremstilling af cystin- eller desaminocystin-holdige peptider eller derivater deraf.
PL13344469A PL88876B1 (cs) 1968-05-10 1969-05-09
NL6907160.A NL165149B (nl) 1968-05-10 1969-05-09 Werkwijze ter bereiding van cystine bevattende peptiden.
BE732851D BE732851A (cs) 1968-05-10 1969-05-09
JP4261571A JPS4811720B1 (cs) 1967-11-09 1971-06-16
US05/206,933 US3956260A (en) 1967-11-09 1971-12-10 Hypocalcaemic peptides and processes for their manufacture
US05/685,857 US4271068A (en) 1968-05-10 1976-05-13 Process for the manufacture of cystine-containing peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH699968A CH498805A (de) 1968-05-10 1968-05-10 Verfahren zur Herstellung von Cystinrest-haltigen Peptiden
US81810969A 1969-04-24 1969-04-24

Publications (1)

Publication Number Publication Date
CH498805A true CH498805A (de) 1970-11-15

Family

ID=25700554

Family Applications (1)

Application Number Title Priority Date Filing Date
CH699968A CH498805A (de) 1967-11-09 1968-05-10 Verfahren zur Herstellung von Cystinrest-haltigen Peptiden

Country Status (2)

Country Link
CH (1) CH498805A (cs)
CS (1) CS150978B2 (cs)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2123498C1 (ru) * 1997-04-10 1998-12-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Защищенные производные вазопрессина
RU2125062C1 (ru) * 1997-04-10 1999-01-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Защищенные производные окситоцина

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2123498C1 (ru) * 1997-04-10 1998-12-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Защищенные производные вазопрессина
RU2125062C1 (ru) * 1997-04-10 1999-01-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Защищенные производные окситоцина

Also Published As

Publication number Publication date
CS150978B2 (cs) 1973-09-17

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