CH537360A - Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts - Google Patents

Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts

Info

Publication number: CH537360A
Authority: CH; Switzerland
Prior art keywords: propanes; cycloalkylamino; phenoxy; hydroxy; preparation
Prior art date: 1969-07-23

Application number

CH1087370A

Other languages

German (de)

Inventor

Herbert Dr Koeppe

Werner Dr Kummer

Helmut Dr Staehle

Zeile Karl Dr Prof

Albrecht Dr Engelhardt

Werner Dr Traunecker

Original Assignee

Boehringer Sohn Ingelheim

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1969-07-23

Filing date

1970-07-16

Publication date

1973-05-31

1970-07-16 Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim

1973-05-31 Publication of CH537360A publication Critical patent/CH537360A/en

Links

239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
- E04H13/00—Monuments; Tombs; Burial vaults; Columbaria
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Architecture (AREA)
Civil Engineering (AREA)
Structural Engineering (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CH1087370A 1969-07-23 1970-07-16 Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts CH537360A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1937477A DE1937477C3 (en)	1969-07-23	1969-07-23	I-phenoxy-2-hydroxy-3- (l -methylcycloalkylamino) propane, process for their preparation and medicaments containing them

Publications (1)

Publication Number	Publication Date
CH537360A true CH537360A (en)	1973-05-31

Family

ID=5740681

Family Applications (10)

Application Number	Title	Priority Date	Filing Date
CH224973A CH550139A (en)	1969-07-23	1970-07-16	PROCESS FOR THE PRODUCTION OF NEW RACEMIC OR OPTICALLY ACTIVE 1-PHENOXY-2-HYDROXY-3-CYCLOALKYLAMINOPROPANES OR. YOUR ACID ADDITION SALT.
CH224473A CH550140A (en)	1969-07-23	1970-07-16	PROCESS FOR THE PRODUCTION OF NEW RACEMIC OR OPTICALLY ACTIVE 1-PHENOXY-2-HYDROXY-3-CYCLOALKYLAMINOPROPANES OR. YOUR ACID ADDITION SALT.
CH1106675A CH575376A5 (en)	1969-07-23	1970-07-16
CH224873A CH536813A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224373A CH570363A5 (en)	1969-07-23	1970-07-16
CH224673A CH536811A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH1087370A CH537360A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224273A CH536809A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224573A CH536810A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224773A CH536812A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts

Family Applications Before (6)

Application Number	Title	Priority Date	Filing Date
CH224973A CH550139A (en)	1969-07-23	1970-07-16	PROCESS FOR THE PRODUCTION OF NEW RACEMIC OR OPTICALLY ACTIVE 1-PHENOXY-2-HYDROXY-3-CYCLOALKYLAMINOPROPANES OR. YOUR ACID ADDITION SALT.
CH224473A CH550140A (en)	1969-07-23	1970-07-16	PROCESS FOR THE PRODUCTION OF NEW RACEMIC OR OPTICALLY ACTIVE 1-PHENOXY-2-HYDROXY-3-CYCLOALKYLAMINOPROPANES OR. YOUR ACID ADDITION SALT.
CH1106675A CH575376A5 (en)	1969-07-23	1970-07-16
CH224873A CH536813A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224373A CH570363A5 (en)	1969-07-23	1970-07-16
CH224673A CH536811A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
CH224273A CH536809A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224573A CH536810A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts
CH224773A CH536812A (en)	1969-07-23	1970-07-16	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylamino-propanes and their acid addition salts

Country Status (17)

Country	Link
US (1)	US3755413A (en)
JP (5)	JPS5133106B1 (en)
AT (9)	AT306704B (en)
BE (1)	BE753774A (en)
BG (9)	BG17508A3 (en)
CH (10)	CH550139A (en)
CS (9)	CS170524B2 (en)
DE (1)	DE1937477C3 (en)
DK (1)	DK140281B (en)
ES (8)	ES382014A1 (en)
FR (1)	FR2059551B1 (en)
GB (1)	GB1314896A (en)
NL (1)	NL169874C (en)
PL (9)	PL90025B1 (en)
RO (9)	RO59089A (en)
SE (1)	SE370391B (en)
YU (5)	YU34395B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3937706A (en) *	1969-07-23	1976-02-10	Boehringer Ingelheim Gmbh	1-(2'ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propanes and salts thereof
US4021576A (en) *	1969-07-23	1977-05-03	Boehringer Ingelheim Gmbh	Pharmaceutical compositions containing a 1-(2'-ethynyl-phenoxy)-2-hydroxy-3-(cycloalkyl-amino)-propane and method of use
US4038313A (en) *	1970-01-08	1977-07-26	Ciba-Geigy Corporation	Cycloalkylureido phenoxy propanolamines
US4120978A (en) *	1970-01-08	1978-10-17	Ciba-Geigy Corporation	Pharmaceutical composition for inhibiting and blocking cardioselective beta-receptors
SE354851B (en) *	1970-02-18	1973-03-26	Haessle Ab
US4145442A (en) *	1972-04-04	1979-03-20	Aktiebolaget Hassle	Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
US4038414A (en) *	1972-06-08	1977-07-26	Ciba-Geigy Corporation	Amines and processes for their manufacture
US4035420A (en) *	1972-07-06	1977-07-12	Aktiebolaget Hassle	Substituted ureido alkylene phenoxy propanolamines
DE2309887C2 (en) *	1973-02-28	1983-11-10	C.H. Boehringer Sohn, 6507 Ingelheim	1-aryloxy-2-hydroxy-3-alkynylaminopropane derivatives and their physiologically acceptable acid addition salts, pharmaceutical preparations and manufacturing processes for the compounds
US4220659A (en) *	1974-02-22	1980-09-02	Boehringer Ingelheim Gmbh	1-Phenoxy-2-hydroxy-3-alkynylamino-propanes and salts thereof
SE7510153L (en) *	1974-09-12	1976-05-07	American Cyanamid Co	ALKANOLAMINES
US4165384A (en) *	1974-11-01	1979-08-21	Aktiebolaget Hassle	Amide substituted phenoxy propanol amines
US4387103A (en) *	1980-11-28	1983-06-07	American Hospital Supply Corporation	Method for treatment or prophylaxis of cardiac disorders
US4471127A (en) *	1981-09-08	1984-09-11	Ciba-Geigy Corporation	1-5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
US5039801A (en) *	1985-12-20	1991-08-13	The United States Of America As Represented By The Department Of Health & Human Services	Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
JPS6364630U (en) *	1986-10-17	1988-04-28

1969
- 1969-07-23 DE DE1937477A patent/DE1937477C3/en not_active Expired
1970
- 1970-03-22 BG BG017138A patent/BG17508A3/en unknown
- 1970-03-23 BG BG017134A patent/BG17750A3/en unknown
- 1970-07-16 CH CH224973A patent/CH550139A/en not_active IP Right Cessation
- 1970-07-16 CH CH224473A patent/CH550140A/en not_active IP Right Cessation
- 1970-07-16 CH CH1106675A patent/CH575376A5/xx not_active IP Right Cessation
- 1970-07-16 CH CH224873A patent/CH536813A/en not_active IP Right Cessation
- 1970-07-16 CH CH224373A patent/CH570363A5/xx not_active IP Right Cessation
- 1970-07-16 CH CH224673A patent/CH536811A/en not_active IP Right Cessation
- 1970-07-16 CH CH1087370A patent/CH537360A/en not_active IP Right Cessation
- 1970-07-16 CH CH224273A patent/CH536809A/en not_active IP Right Cessation
- 1970-07-16 CH CH224573A patent/CH536810A/en not_active IP Right Cessation
- 1970-07-16 CH CH224773A patent/CH536812A/en not_active IP Right Cessation
- 1970-07-20 RO RO69802A patent/RO59089A/ro unknown
- 1970-07-20 RO RO69806A patent/RO59211A/ro unknown
- 1970-07-20 RO RO69804A patent/RO59209A/ro unknown
- 1970-07-20 RO RO63988A patent/RO56318A/ro unknown
- 1970-07-20 RO RO69798A patent/RO60111A/ro unknown
- 1970-07-20 RO RO69801A patent/RO59112A/ro unknown
- 1970-07-20 RO RO69805A patent/RO59210A/ro unknown
- 1970-07-20 RO RO69803A patent/RO59159A/ro unknown
- 1970-07-20 RO RO69799A patent/RO60112A/ro unknown
- 1970-07-21 PL PL1970173772A patent/PL90025B1/pl unknown
- 1970-07-21 CS CS5136A patent/CS170524B2/cs unknown
- 1970-07-21 CS CS4509A patent/CS170532B2/cs unknown
- 1970-07-21 PL PL1970173769A patent/PL90028B1/pl unknown
- 1970-07-21 ES ES382014A patent/ES382014A1/en not_active Expired
- 1970-07-21 PL PL1970173767A patent/PL90030B1/pl unknown
- 1970-07-21 CS CS4508A patent/CS170531B2/cs unknown
- 1970-07-21 CS CS4505A patent/CS170528B2/cs unknown
- 1970-07-21 PL PL1970142196A patent/PL79772B1/pl unknown
- 1970-07-21 GB GB3535970A patent/GB1314896A/en not_active Expired
- 1970-07-21 PL PL1970173765A patent/PL90039B1/pl unknown
- 1970-07-21 CS CS4507A patent/CS170530B2/cs unknown
- 1970-07-21 PL PL1970173768A patent/PL90029B1/pl unknown
- 1970-07-21 CS CS4503A patent/CS170526B2/cs unknown
- 1970-07-21 CS CS4504A patent/CS170527B2/cs unknown
- 1970-07-21 CS CS4502A patent/CS170525B2/cs unknown
- 1970-07-21 PL PL1970173770A patent/PL90027B1/pl unknown
- 1970-07-21 PL PL1970173771A patent/PL90026B1/pl unknown
- 1970-07-21 PL PL1970173766A patent/PL90038B1/pl unknown
- 1970-07-21 CS CS4506A patent/CS170529B2/cs unknown
- 1970-07-22 BG BG017135A patent/BG17751A3/en unknown
- 1970-07-22 BG BG017137A patent/BG18852A3/en unknown
- 1970-07-22 BE BE753774D patent/BE753774A/en not_active IP Right Cessation
- 1970-07-22 JP JP45063634A patent/JPS5133106B1/ja active Pending
- 1970-07-22 BG BG018645A patent/BG19132A3/en unknown
- 1970-07-22 BG BG015254A patent/BG17749A3/en unknown
- 1970-07-22 US US00057353A patent/US3755413A/en not_active Expired - Lifetime
- 1970-07-22 YU YU1860/70A patent/YU34395B/en unknown
- 1970-07-22 DK DK380170AA patent/DK140281B/en unknown
- 1970-07-22 BG BG017136A patent/BG17507A3/en unknown
- 1970-07-23 FR FR7027291A patent/FR2059551B1/fr not_active Expired
- 1970-07-23 AT AT118672A patent/AT306704B/en not_active IP Right Cessation
- 1970-07-23 AT AT118172A patent/AT304474B/en active
- 1970-07-23 AT AT118272A patent/AT304475B/en active
- 1970-07-23 SE SE7010200A patent/SE370391B/xx unknown
- 1970-07-23 AT AT674870A patent/AT303706B/en not_active IP Right Cessation
- 1970-07-23 AT AT118072A patent/AT306703B/en not_active IP Right Cessation
- 1970-07-23 AT AT118372A patent/AT304476B/en not_active IP Right Cessation
- 1970-07-23 AT AT118572A patent/AT304478B/en active
- 1970-07-23 NL NLAANVRAGE7010928,A patent/NL169874C/en not_active IP Right Cessation
- 1970-07-23 AT AT117972A patent/AT306702B/en not_active IP Right Cessation
- 1970-07-23 AT AT118472A patent/AT304477B/en not_active IP Right Cessation
- 1970-07-24 BG BG017132A patent/BG17505A3/en unknown
- 1970-07-24 BG BG017133A patent/BG17506A3/en unknown
1971
- 1971-09-09 ES ES394917A patent/ES394917A1/en not_active Expired
- 1971-09-09 ES ES394919A patent/ES394919A1/en not_active Expired
- 1971-09-09 ES ES394913A patent/ES394913A1/en not_active Expired
- 1971-09-09 ES ES394915A patent/ES394915A1/en not_active Expired
- 1971-09-09 ES ES394918A patent/ES394918A1/en not_active Expired
- 1971-09-09 ES ES394916A patent/ES394916A1/en not_active Expired
- 1971-09-09 ES ES394914A patent/ES394914A1/en not_active Expired
1973
- 1973-06-06 JP JP48063730A patent/JPS5210863B1/ja active Pending
- 1973-06-06 JP JP48063728A patent/JPS5210861B1/ja active Pending
- 1973-06-06 JP JP48063729A patent/JPS5210862B1/ja active Pending
- 1973-06-06 JP JP48063727A patent/JPS5238556B1/ja active Pending
1975
- 1975-10-07 YU YU2546/75A patent/YU34663B/en unknown
- 1975-10-07 YU YU2544/75A patent/YU34396B/en unknown
- 1975-10-07 YU YU2545/75A patent/YU34662B/en unknown
- 1975-10-07 YU YU2551/75A patent/YU34113B/en unknown

Also Published As

Publication number	Publication date
PL90038B1 (en)	1976-12-31
BG17507A3 (en)	1973-11-10
RO59210A (en)	1976-01-15
CH536812A (en)	1973-06-29
BG18852A3 (en)	1975-03-20
BE753774A (en)	1971-01-22
NL7010928A (en)	1971-01-26
DK140281B (en)	1979-07-23
YU34113B (en)	1978-12-31
BG17505A3 (en)	1973-11-10
YU34395B (en)	1979-07-10
PL90029B1 (en)	1976-12-31
YU254575A (en)	1979-04-30
RO59112A (en)	1976-01-15
CS170531B2 (en)	1976-08-27
ES394914A1 (en)	1974-12-01
PL90025B1 (en)	1976-12-31
NL169874B (en)	1982-04-01
ES394919A1 (en)	1974-12-01
US3755413A (en)	1973-08-28
CS170526B2 (en)	1976-08-27
PL90028B1 (en)	1976-12-31
CH536813A (en)	1973-06-29
DE1937477C3 (en)	1980-04-10
JPS5210863B1 (en)	1977-03-26
YU254675A (en)	1979-04-30
PL79772B1 (en)	1975-06-30
CS170528B2 (en)	1976-08-27
BG19132A3 (en)	1975-04-30
ES382014A1 (en)	1973-06-16
YU34662B (en)	1979-12-31
CH550140A (en)	1974-06-14
BG17506A3 (en)	1973-11-10
CH570363A5 (en)	1975-12-15
AT306703B (en)	1973-04-25
YU186070A (en)	1978-12-31
CS170530B2 (en)	1976-08-27
ES394917A1 (en)	1974-12-01
PL90026B1 (en)	1976-12-31
AT304478B (en)	1973-01-10
DK140281C (en)	1979-12-10
FR2059551A1 (en)	1971-06-04
AT304474B (en)	1973-01-10
ES394916A1 (en)	1974-12-16
CH536811A (en)	1973-06-29
CH536809A (en)	1973-06-29
JPS5133106B1 (en)	1976-09-17
CH575376A5 (en)	1976-05-14
AT304475B (en)	1973-01-10
FR2059551B1 (en)	1974-09-20
RO59211A (en)	1976-01-15
AT306702B (en)	1973-04-25
YU254475A (en)	1978-12-31
CS170525B2 (en)	1976-08-27
JPS5210862B1 (en)	1977-03-26
DE1937477B2 (en)	1979-08-02
GB1314896A (en)	1973-04-26
JPS5210861B1 (en)	1977-03-26
ES394913A1 (en)	1974-12-16
AT306704B (en)	1973-04-25
SE370391B (en)	1974-10-14
DE1937477A1 (en)	1971-02-04
BG17749A3 (en)	1973-12-25
ES394915A1 (en)	1974-12-16
RO56318A (en)	1974-09-01
AT304476B (en)	1973-01-10
CS170529B2 (en)	1976-08-27
CS170527B2 (en)	1976-08-27
CS170532B2 (en)	1976-08-27
AT303706B (en)	1972-12-11
CH536810A (en)	1973-06-29
BG17751A3 (en)	1973-12-25
YU255175A (en)	1978-06-30
CS170524B2 (en)	1976-08-27
PL90027B1 (en)	1976-12-31
RO59159A (en)	1976-02-15
RO60112A (en)	1976-08-15
YU34396B (en)	1979-07-10
BG17508A3 (en)	1973-11-10
JPS5238556B1 (en)	1977-09-29
RO59089A (en)	1975-11-15
PL90039B1 (en)	1976-12-31
PL90030B1 (en)	1976-12-31
BG17750A3 (en)	1973-12-25
RO60111A (en)	1976-06-15
YU34663B (en)	1979-12-31
CH550139A (en)	1974-06-14
ES394918A1 (en)	1974-12-01
NL169874C (en)	1982-09-01
RO59209A (en)	1976-01-15
AT304477B (en)	1973-01-10

Legal Events

Date	Code	Title	Description
1985-03-29	PL	Patent ceased

Publication	Publication Date	Title
AT289075B (en)	1971-04-13	Process for the preparation of new racemic or optically active 1-phenoxy-2-aminoalkanes and their acid addition salts
AT298459B (en)	1972-05-10	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-alkylaminopropanes and their acid addition salts
AT319205B (en)	1974-12-10	Process for the preparation of new racemic or optically active 2-alkyl-2-dialkylaminoacet-2 ', 6'-xylidides and their salts
AT301565B (en)	1972-09-11	Process for the preparation of new β-aryl-2-aminoalkoxystyrenes and their salts
AT304475B (en)	1973-01-10	Process for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-cycloalkylaminopropanes and their acid addition salts
AT296256B (en)	1972-02-10	Process for the preparation of new racemic or optically active substituted 3-carbamoylphenoxy-2-hydroxy-aminopropanes and of their acid addition salts
AT304534B (en)	1973-01-10	Process for the preparation of new pyrazole-4-acetic acid derivatives and their salts
AT290529B (en)	1971-06-11	Process for the preparation of new 5-pyridyl-2-imidazolones and their acid addition salts
AT300793B (en)	1972-08-10	Process for the preparation of new thiazolylacetic acid derivatives and their salts
AT301517B (en)	1972-09-11	Process for the preparation of racemic or optically active cis-chrysanthemum acid
AT303012B (en)	1972-11-10	Process for the preparation of new racemic or optically active 1- (2'-nitrilophenoxy) -2-hydroxy-3-ethylaminopropane and its acid addition salts
AT300813B (en)	1972-07-15	PROCESS FOR THE MANUFACTURING OF NEW RACEMIC OR OPTICALLY ACTIVE QUINOLINE DERIVATIVES AND OF ACID ADDITION SALT HIEV
AT317241B (en)	1974-08-26	Process for the preparation of new carbamoyloximes and their acid addition salts
AT289082B (en)	1971-04-13	Process for the preparation of new racemic or optically active 1-nitrilophenoxy-2-hydroxy-3-tert.-butylaminopropanes and their salts
AT308072B (en)	1973-06-25	Process for the preparation of new racemic or optically active 1- (2'-cyano-5'-methylphenoxy) -2-hydroxy-3-alkylaminopropanes and of their acid addition salts
AT316575B (en)	1974-07-25	Process for the preparation of new acylguanidines and their acid addition salts
AT303717B (en)	1972-12-11	Process for the preparation of new 1-aza-9-oxafluorenes and their salts
AT305982B (en)	1973-03-26	Process for the preparation of new 1-sec.amino-2-oxy-3 - [(p-alkenloxy or p-alkinyloxy) -phenyoxy] -propene and their acid addition salts
AT291970B (en)	1971-08-10	Process for the preparation of new racemic or optically active substituted 1-phenoxy-2-hydroxy-3-alkylaminopropanes and of their acid addition salts
AT306718B (en)	1973-04-25	Process for the preparation of new 2-benzyl-4-piperidinols and their salts