CH537396A - Verfahren zur Herstellung von neuen Benzodiazepinderivaten und Salzen davon - Google Patents

Verfahren zur Herstellung von neuen Benzodiazepinderivaten und Salzen davon

Info

Publication number
CH537396A
CH537396A CH730170A CH730170A CH537396A CH 537396 A CH537396 A CH 537396A CH 730170 A CH730170 A CH 730170A CH 730170 A CH730170 A CH 730170A CH 537396 A CH537396 A CH 537396A
Authority
CH
Switzerland
Prior art keywords
salts
preparation
benzodiazepine derivatives
new benzodiazepine
new
Prior art date
Application number
CH730170A
Other languages
English (en)
Inventor
Yamamoto Hisao
Inaba Shigeho
Hirohashi Toshiyuki
Yamamoto Michiniro
Ishizumi Kikuo
Akatsu Mitsuhiro
Maruyama Isamu
Kume Yoshiharu
Mori Kazuo
Izumi Takahiro
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of CH537396A publication Critical patent/CH537396A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/36Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing an indole or hydrogenated indole ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH730170A 1969-05-16 1970-05-15 Verfahren zur Herstellung von neuen Benzodiazepinderivaten und Salzen davon CH537396A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP44038183A JPS4811718B1 (de) 1969-05-16 1969-05-16

Publications (1)

Publication Number Publication Date
CH537396A true CH537396A (de) 1973-05-31

Family

ID=12518255

Family Applications (1)

Application Number Title Priority Date Filing Date
CH730170A CH537396A (de) 1969-05-16 1970-05-15 Verfahren zur Herstellung von neuen Benzodiazepinderivaten und Salzen davon

Country Status (12)

Country Link
JP (1) JPS4811718B1 (de)
AT (2) AT300815B (de)
BE (1) BE750524A (de)
CA (1) CA946844A (de)
CH (1) CH537396A (de)
CS (1) CS169804B2 (de)
ES (2) ES379701A1 (de)
FR (1) FR2051534B1 (de)
GB (1) GB1272887A (de)
NL (1) NL161749C (de)
SE (1) SE372269B (de)
ZA (1) ZA703130B (de)

Also Published As

Publication number Publication date
FR2051534B1 (de) 1974-04-12
DE2023182B2 (de) 1975-08-28
BE750524A (fr) 1970-10-16
ZA703130B (en) 1971-01-27
GB1272887A (en) 1972-05-03
CS169804B2 (de) 1976-07-29
SE372269B (de) 1974-12-16
NL161749C (nl) 1980-03-17
NL161749B (nl) 1979-10-15
NL7007057A (de) 1970-11-18
DE2023182A1 (de) 1970-11-19
JPS4811718B1 (de) 1973-04-14
ES383587A1 (es) 1973-01-01
ES379701A1 (es) 1972-08-01
AT308125B (de) 1973-06-25
FR2051534A1 (de) 1971-04-09
CA946844A (en) 1974-05-07
AT300815B (de) 1972-08-10

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Legal Events

Date Code Title Description
PL Patent ceased