CH558365A - Procedimento per l'ottenimento di nuovi derivati con azione antiinfiammatoria, costituiti da enolati di 1-benzil-3-(3'(nrr1)-propossi)-1h-indazolo con (4-(n-butil)-1,2-difenil)-,(4-(n-butil)-1-(p-idrossifenil)-2-fenil)- o(4-(-osso-n-butil)-1,2-difenil)-pirazolidina-3,5-dione. - Google Patents
Procedimento per l'ottenimento di nuovi derivati con azione antiinfiammatoria, costituiti da enolati di 1-benzil-3-(3'(nrr1)-propossi)-1h-indazolo con (4-(n-butil)-1,2-difenil)-,(4-(n-butil)-1-(p-idrossifenil)-2-fenil)- o(4-(-osso-n-butil)-1,2-difenil)-pirazolidina-3,5-dione.Info
- Publication number
- CH558365A CH558365A CH736370A CH736370A CH558365A CH 558365 A CH558365 A CH 558365A CH 736370 A CH736370 A CH 736370A CH 736370 A CH736370 A CH 736370A CH 558365 A CH558365 A CH 558365A
- Authority
- CH
- Switzerland
- Prior art keywords
- dione
- indazole
- enolates
- corresp
- pyrazolidone
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- VMFUIVQOYGVESW-UHFFFAOYSA-N 3-propoxy-1H-indazol-4-amine Chemical compound NC1=C2C(=NNC2=CC=C1)OCCC VMFUIVQOYGVESW-UHFFFAOYSA-N 0.000 title 1
- CYMJPJKHCSDSRG-UHFFFAOYSA-N pyrazolidine-3,4-dione Chemical compound O=C1CNNC1=O CYMJPJKHCSDSRG-UHFFFAOYSA-N 0.000 title 1
- 208000008035 Back Pain Diseases 0.000 abstract 1
- 208000008930 Low Back Pain Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 201000005060 thrombophlebitis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/34—Oxygen atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
- C07D231/36—Oxygen atoms with hydrocarbon radicals, substituted by hetero atoms, attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES69367372A ES367372A1 (es) | 1969-05-16 | 1969-05-16 | Procedimiento para la obtencion de nuevos derivados con ac-cion antiinflamatoria, constituidos por enolatos de aminas de la serie de la bencidamina con la fenilbutazona, la p-hi-droxifenilbutazona y la cetofenilbotazona. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH558365A true CH558365A (it) | 1975-01-31 |
Family
ID=8452785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH736370A CH558365A (it) | 1969-05-16 | 1970-05-16 | Procedimento per l'ottenimento di nuovi derivati con azione antiinfiammatoria, costituiti da enolati di 1-benzil-3-(3'(nrr1)-propossi)-1h-indazolo con (4-(n-butil)-1,2-difenil)-,(4-(n-butil)-1-(p-idrossifenil)-2-fenil)- o(4-(-osso-n-butil)-1,2-difenil)-pirazolidina-3,5-dione. |
Country Status (2)
| Country | Link |
|---|---|
| CH (1) | CH558365A (it) |
| ES (1) | ES367372A1 (it) |
-
1969
- 1969-05-16 ES ES69367372A patent/ES367372A1/es not_active Expired
-
1970
- 1970-05-16 CH CH736370A patent/CH558365A/it not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES367372A1 (es) | 1972-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |