CH599247A5 - - Google Patents

Info

Publication number
CH599247A5
CH599247A5 CH1292274A CH1292274A CH599247A5 CH 599247 A5 CH599247 A5 CH 599247A5 CH 1292274 A CH1292274 A CH 1292274A CH 1292274 A CH1292274 A CH 1292274A CH 599247 A5 CH599247 A5 CH 599247A5
Authority
CH
Switzerland
Application number
CH1292274A
Inventor
Jerome Anthony Iacobelli
Thomas Albert Narwid
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH599247A5 publication Critical patent/CH599247A5/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CH1292274A 1973-11-12 1974-09-24 CH599247A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US415186A US3887545A (en) 1973-11-12 1973-11-12 Synthesis of 1{60 -hydroxylated cholesterol derivatives

Publications (1)

Publication Number Publication Date
CH599247A5 true CH599247A5 (fr) 1978-05-31

Family

ID=23644712

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1292274A CH599247A5 (fr) 1973-11-12 1974-09-24

Country Status (9)

Country Link
US (1) US3887545A (fr)
JP (1) JPS5438098B2 (fr)
AT (1) AT342793B (fr)
BE (1) BE821983A (fr)
CH (1) CH599247A5 (fr)
DE (1) DE2453648C3 (fr)
FR (1) FR2250764B1 (fr)
GB (1) GB1443680A (fr)
NL (1) NL7414675A (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
US4264512A (en) * 1975-09-29 1981-04-28 The Regents Of The University Of California 3-Deoxy-1α-hydroxy- and 3-deoxy-1α,25-dihydroxycholecalciferol and processes for the preparation thereof
JPS603045B2 (ja) * 1976-04-19 1985-01-25 中外製薬株式会社 １α―ヒドロキシビタミンＤ類軟カプセルの製造方法
US4098801A (en) * 1977-01-26 1978-07-04 Hoffmann-La Roche Inc. Synthesis of 1α-hydroxylated derivatives of cholesterol
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
LU80545A1 (de) * 1978-11-17 1980-06-05 Hoffmann La Roche Verfahren zur herstellung von 1a,3s-dihydroxy->5-steroiden
US4217279A (en) * 1978-12-18 1980-08-12 Kaiser Emil T Synthesis of steroids
US5952317A (en) * 1995-09-21 1999-09-14 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
US5976784A (en) * 1996-09-20 1999-11-02 Wisconsin Alumni Research Foundation Calcitriol derivatives and their uses
EP0946584B1 (fr) 1996-12-20 2003-04-23 Novo Nordisk A/S Composés regulateurs de meiose
IL146223A0 (en) * 1999-04-30 2002-07-25 Arch Dev Corp Steroid derivatives
CN1498222A (zh) * 2001-02-08 2004-05-19 芝加哥大学 类固醇衍生物
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
CA2482195A1 (fr) * 2002-04-12 2003-10-23 The University Of Chicago Agonistes de recepteur active frx (farnesoid x receptor)
EP1556057A4 (fr) * 2002-08-29 2009-07-15 Univ California Agents et procedes pour stimuler la formation osseuse
WO2005020928A2 (fr) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents et procedes permettant d'ameliorer la formation osseuse a l'aide d'oxysterols combines a des proteines morphogeniques osseuses
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
US20090035155A1 (en) * 2005-04-23 2009-02-05 Ixetic Mac Gmbh Axial piston motor
EP1931353A4 (fr) * 2005-09-02 2009-07-29 Univ California Oxysterols osteogeniques et anti-adipogeniques
CA2643732C (fr) * 2006-02-27 2012-08-21 The Regents Of The University Of California Composes oxysterols et voie
US20100048944A1 (en) * 2006-07-19 2010-02-25 Farhad Parhami Interactions of hedgehog and liver x receptor signaling pathways
WO2008082520A2 (fr) 2006-12-19 2008-07-10 The Regents Of The University Of California Inhibition de l'expression de ppar gamma par des oxystérols ostéogènes spécifiques
WO2008115469A2 (fr) * 2007-03-16 2008-09-25 The Regents Of The University Of California Rôle de la signalisation par hérisson dans l'athérosclérose et les maladies cardiovasculaires
CA2707663C (fr) * 2007-12-03 2017-05-30 The Regents Of The University Of California Oxysterols pour l'activation du signal hedgehog, de l'osteoinduction, de l'anti-adipogenese et du signal wnt
EP2459581A4 (fr) * 2009-07-29 2012-12-26 Univ Chicago Agonistes du récepteur x du foie
JP6262723B2 (ja) 2012-05-07 2018-01-17 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ オキシステロールアナログｏｘｙ１３３は、骨発生及びヘッジホッグシグナル伝達を誘導し、脂肪生成を阻害する
AU2014259672A1 (en) 2013-05-02 2015-12-03 The Regents Of The University Of California Bone-selective osteogenic oxysterol-bone targeting agents
CN114315947B (zh) * 2021-11-17 2023-10-03 王涛 一种由22-甾醇作为原料合成胆固醇和25-羟基胆固醇的新方法
US20250154193A1 (en) * 2022-01-28 2025-05-15 Cholesgen (Shanghai) Co., Ltd. Steroid compound, and preparation method therefor and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080937A (en) * 1960-11-07 1963-03-12 Garbell Res Foundation Combined acoustic wall and exhaust gas deflector in operation of jet engines
US3741996A (en) * 1971-12-02 1973-06-26 Wisconsin Alumni Res Found 1{60 -hydroxycholecalciferol

Also Published As

Publication number Publication date
ATA899274A (de) 1977-08-15
JPS5077360A (fr) 1975-06-24
NL7414675A (nl) 1975-05-14
FR2250764B1 (fr) 1979-08-03
JPS5438098B2 (fr) 1979-11-19
DE2453648A1 (de) 1975-05-15
DE2453648B2 (de) 1980-06-26
BE821983A (fr) 1975-05-09
GB1443680A (en) 1976-07-21
DE2453648C3 (de) 1981-08-06
FR2250764A1 (fr) 1975-06-06
AT342793B (de) 1978-04-25
US3887545A (en) 1975-06-03

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Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased