CH608240A5 - Process for the preparation of pyridinylthiomethyl derivatives of cyanomethylthioacetylcephalosporins - Google Patents
Process for the preparation of pyridinylthiomethyl derivatives of cyanomethylthioacetylcephalosporinsInfo
- Publication number
- CH608240A5 CH608240A5 CH1032075A CH1032075A CH608240A5 CH 608240 A5 CH608240 A5 CH 608240A5 CH 1032075 A CH1032075 A CH 1032075A CH 1032075 A CH1032075 A CH 1032075A CH 608240 A5 CH608240 A5 CH 608240A5
- Authority
- CH
- Switzerland
- Prior art keywords
- formula
- compound
- acylation
- compounds
- see below
- Prior art date
Links
- -1 pyridinylthiomethyl Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000006181 N-acylation Effects 0.000 abstract 2
- 125000005042 acyloxymethyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- HPXRVTGHNJAIIH-UHFFFAOYSA-N cyclohexanol Chemical compound OC1CCCCC1 HPXRVTGHNJAIIH-UHFFFAOYSA-N 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- FGVVTMRZYROCTH-UHFFFAOYSA-N pyridine-2-thiol N-oxide Chemical compound [O-][N+]1=CC=CC=C1S FGVVTMRZYROCTH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49935474A | 1974-08-21 | 1974-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH608240A5 true CH608240A5 (en) | 1978-12-29 |
Family
ID=23984947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH1032075A CH608240A5 (en) | 1974-08-21 | 1975-08-07 | Process for the preparation of pyridinylthiomethyl derivatives of cyanomethylthioacetylcephalosporins |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS5143795A (fr) |
| AU (1) | AU497282B2 (fr) |
| BE (1) | BE832615A (fr) |
| CA (1) | CA1057739A (fr) |
| CH (1) | CH608240A5 (fr) |
| DE (1) | DE2537280A1 (fr) |
| FR (1) | FR2282274A1 (fr) |
| GB (1) | GB1507925A (fr) |
| NL (1) | NL7508109A (fr) |
-
1975
- 1975-05-19 GB GB2125475A patent/GB1507925A/en not_active Expired
- 1975-06-16 AU AU82257/75A patent/AU497282B2/en not_active Expired
- 1975-06-18 CA CA229,637A patent/CA1057739A/fr not_active Expired
- 1975-07-08 NL NL7508109A patent/NL7508109A/xx not_active Application Discontinuation
- 1975-08-07 CH CH1032075A patent/CH608240A5/xx not_active IP Right Cessation
- 1975-08-19 FR FR7525670A patent/FR2282274A1/fr not_active Withdrawn
- 1975-08-21 JP JP10198075A patent/JPS5143795A/ja active Pending
- 1975-08-21 DE DE19752537280 patent/DE2537280A1/de not_active Withdrawn
- 1975-08-21 BE BE159353A patent/BE832615A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1057739A (fr) | 1979-07-03 |
| AU497282B2 (en) | 1978-12-07 |
| JPS5143795A (ja) | 1976-04-14 |
| DE2537280A1 (de) | 1976-03-04 |
| NL7508109A (nl) | 1976-02-24 |
| FR2282274A1 (fr) | 1976-03-19 |
| AU8225775A (en) | 1976-12-23 |
| BE832615A (fr) | 1975-12-16 |
| GB1507925A (en) | 1978-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |