CH610877A5 - Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid - Google Patents
Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acidInfo
- Publication number
- CH610877A5 CH610877A5 CH379076A CH379076A CH610877A5 CH 610877 A5 CH610877 A5 CH 610877A5 CH 379076 A CH379076 A CH 379076A CH 379076 A CH379076 A CH 379076A CH 610877 A5 CH610877 A5 CH 610877A5
- Authority
- CH
- Switzerland
- Prior art keywords
- acid
- dichloroanilino
- compound
- preparation
- addition salts
- Prior art date
Links
- DCOPUUMXTXDBNB-UHFFFAOYSA-N diclofenac Chemical compound OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl DCOPUUMXTXDBNB-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- HOLHYSJJBXSLMV-UHFFFAOYSA-N 2,6-dichlorophenol Chemical compound OC1=C(Cl)C=CC=C1Cl HOLHYSJJBXSLMV-UHFFFAOYSA-N 0.000 abstract 1
- 238000006816 Chapman rearrangement reaction Methods 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/12—Formation of amino and carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50038682A JPS51113842A (en) | 1975-03-31 | 1975-03-31 | Process for preparing o-(2,6-dichloroanilino)phenyl acetic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH610877A5 true CH610877A5 (en) | 1979-05-15 |
Family
ID=12532044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH379076A CH610877A5 (en) | 1975-03-31 | 1976-03-26 | Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and of the addition salts of this acid |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS51113842A (fr) |
| AU (1) | AU504223B2 (fr) |
| CA (1) | CA1050565A (fr) |
| CH (1) | CH610877A5 (fr) |
| DE (1) | DE2613838A1 (fr) |
| DK (1) | DK157576A (fr) |
| FI (1) | FI760842A7 (fr) |
| FR (1) | FR2306196A1 (fr) |
| GB (1) | GB1532087A (fr) |
| GR (1) | GR59322B (fr) |
| NL (1) | NL7603348A (fr) |
| NO (1) | NO144667C (fr) |
| SE (1) | SE413314B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5815940A (ja) | 1981-07-23 | 1983-01-29 | Eisai Co Ltd | ポリプレニル系化合物およびその製造方法ならびにそれを含有する医薬 |
| ATE116636T1 (de) * | 1989-01-27 | 1995-01-15 | Heumann Pharma Gmbh & Co | Verfahren zur herstellung von 2,6- dichlordiphenylaminessigsäurederivaten. |
| CN108947861A (zh) * | 2018-08-17 | 2018-12-07 | 复旦大学 | 双氯芬酸钠的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1053269A (fr) * | 1964-11-27 |
-
1975
- 1975-03-31 JP JP50038682A patent/JPS51113842A/ja active Granted
-
1976
- 1976-03-25 AU AU12370/76A patent/AU504223B2/en not_active Expired
- 1976-03-26 CH CH379076A patent/CH610877A5/xx not_active IP Right Cessation
- 1976-03-26 GB GB12175/76A patent/GB1532087A/en not_active Expired
- 1976-03-26 GR GR50400A patent/GR59322B/el unknown
- 1976-03-30 SE SE7603779A patent/SE413314B/xx unknown
- 1976-03-30 CA CA249,128A patent/CA1050565A/fr not_active Expired
- 1976-03-30 FI FI760842A patent/FI760842A7/fi not_active Application Discontinuation
- 1976-03-30 NO NO761097A patent/NO144667C/no unknown
- 1976-03-31 DE DE19762613838 patent/DE2613838A1/de not_active Withdrawn
- 1976-03-31 FR FR7609273A patent/FR2306196A1/fr active Granted
- 1976-03-31 DK DK157576A patent/DK157576A/da not_active IP Right Cessation
- 1976-03-31 NL NL7603348A patent/NL7603348A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2306196B1 (fr) | 1979-06-29 |
| GB1532087A (en) | 1978-11-15 |
| GR59322B (en) | 1977-12-13 |
| SE413314B (sv) | 1980-05-19 |
| NO144667B (no) | 1981-07-06 |
| CA1050565A (fr) | 1979-03-13 |
| AU1237076A (en) | 1977-09-29 |
| DE2613838A1 (de) | 1976-10-07 |
| JPS51113842A (en) | 1976-10-07 |
| FI760842A7 (fr) | 1976-10-01 |
| FR2306196A1 (fr) | 1976-10-29 |
| SE7603779L (sv) | 1976-10-01 |
| NO144667C (no) | 1981-10-14 |
| NO761097L (fr) | 1976-10-01 |
| AU504223B2 (en) | 1979-10-04 |
| NL7603348A (nl) | 1976-10-04 |
| DK157576A (da) | 1976-10-01 |
| JPS565218B2 (fr) | 1981-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |