CH618183A5 - - Google Patents

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Publication number
CH618183A5
CH618183A5 CH1580574A CH1580574A CH618183A5 CH 618183 A5 CH618183 A5 CH 618183A5 CH 1580574 A CH1580574 A CH 1580574A CH 1580574 A CH1580574 A CH 1580574A CH 618183 A5 CH618183 A5 CH 618183A5
Authority
CH
Switzerland
Prior art keywords
homo
acid
carbon
hydrogen
hydroxy
Prior art date
Application number
CH1580574A
Other languages
German (de)
English (en)
Inventor
Ulrich Dr Kerb
Rudolf Prof Dr Wiechert
Klaus Dr Kieslich
Karl Dr Petzoldt
Helmut Dr Wachtel
Dieter Dr Palenschat
Reinhard Dr Horowski
Gert Dr Paschelke
Wolfgang Dr Kehr
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2360443A external-priority patent/DE2360443A1/de
Priority claimed from DE19742445161 external-priority patent/DE2445161A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of CH618183A5 publication Critical patent/CH618183A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
CH1580574A 1973-11-30 1974-11-28 CH618183A5 (2)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2360443A DE2360443A1 (de) 1973-11-30 1973-11-30 D-homo-20-ketopregnane
DE19742445161 DE2445161A1 (de) 1974-09-19 1974-09-19 D-homo-20-ketopregnane ii

Publications (1)

Publication Number Publication Date
CH618183A5 true CH618183A5 (2) 1980-07-15

Family

ID=25766200

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1580574A CH618183A5 (2) 1973-11-30 1974-11-28

Country Status (14)

Country Link
US (1) US4045574A (2)
JP (1) JPS5084561A (2)
AT (1) AT347611B (2)
CA (1) CA1030522A (2)
CH (1) CH618183A5 (2)
DD (1) DD115659A5 (2)
DK (1) DK134348C (2)
ES (1) ES432106A1 (2)
FR (1) FR2253512B1 (2)
GB (1) GB1494097A (2)
IE (1) IE40423B1 (2)
IL (1) IL46153A (2)
NL (1) NL7415577A (2)
SE (1) SE408426B (2)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
DE60308388T2 (de) * 2002-08-16 2007-09-20 Pharmacia & Upjohn Co. Llc, Kalamazoo 5-Androsten-3beta-ol-Steroide und Verfahren für ihre Herstellung
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SMT202100509T1 (it) 2013-04-17 2021-11-12 Sage Therapeutics Inc Steroide di c21-n-pirazolile 19-nor c3,3-disostituito per l'uso in terapia
CN117304245A (zh) 2013-04-17 2023-12-29 萨奇治疗股份有限公司 刺激神经活性的19-去甲类固醇及其使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
CA2918735C (en) 2013-07-19 2023-08-01 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN105579043B (zh) 2013-08-23 2021-09-14 萨奇治疗股份有限公司 神经活性类固醇、组合物和其用途
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US20170233433A1 (en) 2014-10-16 2017-08-17 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
MY190408A (en) 2014-10-16 2022-04-21 Sage Therapeutics Inc Compositions and methods for treating cns disorders
WO2016082789A1 (en) 2014-11-27 2016-06-02 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
LT3250210T (lt) 2015-01-26 2021-04-12 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti gydyti cns sutrikimus
DK3258939T3 (da) 2015-02-20 2022-12-12 Sage Therapeutics Inc Neuroaktive steroider, sammensætninger og anvendelser heraf
WO2018013613A1 (en) 2016-07-11 2018-01-18 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
CA3030420C (en) 2016-07-11 2025-11-18 Sage Therapeutics, Inc. C7, C12 AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND ASSOCIATED METHODS OF USE
EP3728285B1 (en) * 2017-12-22 2026-04-08 Sage Therapeutics, LLC Compositions and methods for treating cns disorders
IL312610B2 (en) 2018-12-05 2026-05-01 Sage Therapeutics Llc Neuroactive steroids and methods of using them
CN111410678B (zh) 2019-01-08 2023-02-28 成都康弘药业集团股份有限公司 甾体类化合物、用途及其制备方法
JP7670626B2 (ja) 2019-05-31 2025-04-30 セージ セラピューティクス, インコーポレイテッド 神経刺激性ステロイド及びその組成物
BR112021026447A2 (pt) * 2019-06-27 2022-04-12 Sage Therapeutics Inc Composições e métodos para tratamento de distúrbios de cns
JP7787635B2 (ja) 2019-06-27 2025-12-17 セージ セラピューティクス, エルエルシー Cns障害を治療するための組成物及び方法
CA3143545A1 (en) * 2019-06-27 2020-12-30 Sage Therapeutics, Inc. Compounds for treating cns disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same

Also Published As

Publication number Publication date
DK604174A (2) 1975-07-28
GB1494097A (en) 1977-12-07
FR2253512B1 (2) 1978-02-03
IL46153A (en) 1979-01-31
DK134348B (da) 1976-10-25
FR2253512A1 (2) 1975-07-04
DK134348C (da) 1977-03-21
IL46153A0 (en) 1975-02-10
US4045574A (en) 1977-08-30
NL7415577A (nl) 1975-06-03
JPS5084561A (2) 1975-07-08
DD115659A5 (2) 1975-10-12
SE408426B (sv) 1979-06-11
AU7586774A (en) 1976-06-03
IE40423B1 (en) 1979-05-23
ATA950774A (de) 1978-05-15
IE40423L (en) 1975-05-30
SE7414960L (2) 1975-06-02
AT347611B (de) 1979-01-10
ES432106A1 (es) 1976-11-01
CA1030522A (en) 1978-05-02

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