CH624772A5 - - Google Patents

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Info

Publication number: CH624772A5
Authority: CH; Switzerland
Prior art keywords: solution; oxidized; blood; streptolysin; sodium
Prior art date: 1975-12-22

Application number

CH1591976A

Other languages

English (en)

Italian (it)

Inventor

Antonio Ricci

Original Assignee

Sclavo Inst Sieroterapeut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-12-22

Filing date

1976-12-17

Publication date

1981-08-14

1976-12-17 Application filed by Sclavo Inst Sieroterapeut filed Critical Sclavo Inst Sieroterapeut

1981-08-14 Publication of CH624772A5 publication Critical patent/CH624772A5/it

Links

210000003743 erythrocyte Anatomy 0.000 claims description 26
210000004369 blood Anatomy 0.000 claims description 25
239000008280 blood Substances 0.000 claims description 25
238000000034 method Methods 0.000 claims description 21
239000000243 solution Substances 0.000 claims description 20
206010018910 Haemolysis Diseases 0.000 claims description 12
239000003638 chemical reducing agent Substances 0.000 claims description 12
230000008588 hemolysis Effects 0.000 claims description 12
GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims description 10
238000010790 dilution Methods 0.000 claims description 9
239000012895 dilution Substances 0.000 claims description 9
230000002949 hemolytic effect Effects 0.000 claims description 7
235000010265 sodium sulphite Nutrition 0.000 claims description 5
DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 claims description 4
HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 claims description 4
235000010262 sodium metabisulphite Nutrition 0.000 claims description 4
DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 claims description 4
PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims description 3
229960004308 acetylcysteine Drugs 0.000 claims description 3
-1 cistern Chemical compound 0.000 claims description 3
238000004062 sedimentation Methods 0.000 claims description 3
125000003396 thiol group Chemical group [H]S* 0.000 claims description 3
150000003573 thiols Chemical class 0.000 claims description 3
XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims description 2
239000004472 Lysine Substances 0.000 claims description 2
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 2
235000018417 cysteine Nutrition 0.000 claims description 2
239000003085 diluting agent Substances 0.000 claims description 2
239000004296 sodium metabisulphite Substances 0.000 claims description 2
239000002904 solvent Substances 0.000 claims description 2
VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 claims 2
229940001584 sodium metabisulfite Drugs 0.000 claims 2
150000001875 compounds Chemical class 0.000 claims 1
229960002433 cysteine Drugs 0.000 claims 1
210000002966 serum Anatomy 0.000 description 21
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 8
238000006243 chemical reaction Methods 0.000 description 7
231100000765 toxin Toxicity 0.000 description 7
239000003053 toxin Substances 0.000 description 7
241000283973 Oryctolagus cuniculus Species 0.000 description 4
210000000170 cell membrane Anatomy 0.000 description 4
235000012000 cholesterol Nutrition 0.000 description 4
102000006240 membrane receptors Human genes 0.000 description 4
108020004084 membrane receptors Proteins 0.000 description 4
238000005406 washing Methods 0.000 description 3
241001465754 Metazoa Species 0.000 description 2
238000005119 centrifugation Methods 0.000 description 2
230000000295 complement effect Effects 0.000 description 2
210000000624 ear auricle Anatomy 0.000 description 2
230000008030 elimination Effects 0.000 description 2
238000003379 elimination reaction Methods 0.000 description 2
125000000524 functional group Chemical group 0.000 description 2
230000002779 inactivation Effects 0.000 description 2
239000000463 material Substances 0.000 description 2
239000012528 membrane Substances 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
238000000926 separation method Methods 0.000 description 2
239000006228 supernatant Substances 0.000 description 2
238000004448 titration Methods 0.000 description 2
210000001364 upper extremity Anatomy 0.000 description 2
ZSLUVFAKFWKJRC-IGMARMGPSA-N 232Th Chemical compound [232Th] ZSLUVFAKFWKJRC-IGMARMGPSA-N 0.000 description 1
102000001554 Hemoglobins Human genes 0.000 description 1
108010054147 Hemoglobins Proteins 0.000 description 1
DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 1
241001505901 Streptococcus sp. 'group A' Species 0.000 description 1
229910052776 Thorium Inorganic materials 0.000 description 1
230000004075 alteration Effects 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
238000010171 animal model Methods 0.000 description 1
239000008366 buffered solution Substances 0.000 description 1
210000004027 cell Anatomy 0.000 description 1
238000004113 cell culture Methods 0.000 description 1
230000009089 cytolysis Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000007865 diluting Methods 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
238000009826 distribution Methods 0.000 description 1
125000002228 disulfide group Chemical group 0.000 description 1
238000011534 incubation Methods 0.000 description 1
230000003993 interaction Effects 0.000 description 1
231100000518 lethal Toxicity 0.000 description 1
230000001665 lethal effect Effects 0.000 description 1
210000000265 leukocyte Anatomy 0.000 description 1
150000002632 lipids Chemical class 0.000 description 1
230000002101 lytic effect Effects 0.000 description 1
238000006386 neutralization reaction Methods 0.000 description 1
230000003472 neutralizing effect Effects 0.000 description 1
239000007800 oxidant agent Substances 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
239000000047 product Substances 0.000 description 1
231100000654 protein toxin Toxicity 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
239000007858 starting material Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
230000000007 visual effect Effects 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56944—Streptococcus
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/554—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being a biological cell or cell fragment, e.g. bacteria, yeast cells
- G01N33/555—Red blood cell
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Chemical & Material Sciences (AREA)
Cell Biology (AREA)
Microbiology (AREA)
General Physics & Mathematics (AREA)
Biochemistry (AREA)
Pathology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Mycology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)

CH1591976A 1975-12-22 1976-12-17 CH624772A5 (el)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT09660/75A IT1155243B (it)	1975-12-22	1975-12-22	Attrezzatura per la titolazione degli anti corpi antistreptolisinici e metodo di titolazione con l impiego dei componenti di detta attrezzatura

Publications (1)

Publication Number	Publication Date
CH624772A5 true CH624772A5 (el)	1981-08-14

Family

ID=11132951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH1591976A CH624772A5 (el)	1975-12-22	1976-12-17

Country Status (23)

Country	Link
US (2)	US4148609A (el)
AR (1)	AR219288A1 (el)
AT (1)	AT352903B (el)
AU (1)	AU509644B2 (el)
BE (1)	BE849754A (el)
BR (1)	BR7608652A (el)
CA (1)	CA1076025A (el)
CH (1)	CH624772A5 (el)
DE (1)	DE2657926C3 (el)
DK (1)	DK145276C (el)
ES (1)	ES454866A1 (el)
FI (1)	FI60449C (el)
FR (1)	FR2336685A1 (el)
GB (1)	GB1531530A (el)
GR (1)	GR59855B (el)
IT (1)	IT1155243B (el)
LU (1)	LU76434A1 (el)
NL (1)	NL169787C (el)
NO (1)	NO146581C (el)
PT (1)	PT65994B (el)
SE (1)	SE420953B (el)
TR (1)	TR19262A (el)
ZA (1)	ZA767051B (el)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1132167B (it) *	1980-07-03	1986-06-25	Diesse Diagnostica Senese Srl	Metodo emolitico per la determinazione in continuo degli anticorpi antistreptolisina o,in campioni di sangue o di siero con impiego di streptolisina o ossidata
IT1218273B (it) *	1981-05-07	1990-04-12	Sclavo Inst Sieroterapeut	Metodo integrato per l'analisi degli anticorpi antistreptolisinici e mezzi adatti allo scopo
DE3210080A1 (de) *	1982-03-19	1983-09-22	Behringwerke Ag, 3550 Marburg	Anti-streptolysin o-latex-reagenz und verfahren zu seiner herstellung
US4554248A (en) *	1982-11-08	1985-11-19	American Home Products Corporation	Composition and method for detecting Antistreptolysin O
ES2037045T3 (es) *	1986-09-24	1993-06-16	Wako Pure Chemical Industries, Ltd.	Metodo nuevo para la determinacion del valor de antistreptolisina y un estuche utilizado para ello.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3789116A (en) *	1970-12-09	1974-01-29	Abbott Lab	Fluorescent labeled antibody reagent
US3925161A (en) *	1973-07-18	1975-12-09	Mary M Galvani	Fecal streptococci speciating media
US4038147A (en) *	1976-06-15	1977-07-26	Becton, Dickinson And Company	Method for detecting endotoxins

1975
- 1975-12-21 TR TR19262A patent/TR19262A/xx unknown
- 1975-12-22 IT IT09660/75A patent/IT1155243B/it active
1976
- 1976-11-24 ZA ZA767051A patent/ZA767051B/xx unknown
- 1976-11-25 GR GR52267A patent/GR59855B/el unknown
- 1976-12-02 US US05/747,048 patent/US4148609A/en not_active Expired - Lifetime
- 1976-12-02 CA CA267,005A patent/CA1076025A/en not_active Expired
- 1976-12-03 AU AU20231/76A patent/AU509644B2/en not_active Expired
- 1976-12-07 GB GB51063/76A patent/GB1531530A/en not_active Expired
- 1976-12-17 CH CH1591976A patent/CH624772A5/it not_active IP Right Cessation
- 1976-12-17 ES ES454866A patent/ES454866A1/es not_active Expired
- 1976-12-20 PT PT65994A patent/PT65994B/pt unknown
- 1976-12-20 NL NLAANVRAGE7614167,A patent/NL169787C/xx active
- 1976-12-20 LU LU76434A patent/LU76434A1/xx unknown
- 1976-12-20 AR AR265936A patent/AR219288A1/es active
- 1976-12-20 NO NO764314A patent/NO146581C/no unknown
- 1976-12-20 FI FI763646A patent/FI60449C/fi not_active IP Right Cessation
- 1976-12-21 AT AT948876A patent/AT352903B/de not_active IP Right Cessation
- 1976-12-21 DE DE2657926A patent/DE2657926C3/de not_active Expired
- 1976-12-21 DK DK577376A patent/DK145276C/da active
- 1976-12-21 FR FR7638584A patent/FR2336685A1/fr active Granted
- 1976-12-21 SE SE7614389A patent/SE420953B/xx not_active IP Right Cessation
- 1976-12-22 BR BR7608652A patent/BR7608652A/pt unknown
- 1976-12-22 BE BE173554A patent/BE849754A/xx not_active IP Right Cessation
1981
- 1981-04-08 US US06/252,219 patent/USRE31372E/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FR2336685B1 (el)	1979-03-09
BE849754A (fr)	1977-06-22
SE420953B (sv)	1981-11-09
NO764314L (el)	1977-06-23
DE2657926C3 (de)	1979-02-08
NL169787C (nl)	1982-08-16
GR59855B (en)	1978-03-07
AR219288A1 (es)	1980-08-15
AU2023176A (en)	1978-06-08
CA1076025A (en)	1980-04-22
USRE31372E (en)	1983-09-06
AT352903B (de)	1979-10-10
AU509644B2 (en)	1980-05-22
DE2657926A1 (de)	1977-07-07
PT65994A (en)	1977-01-01
LU76434A1 (el)	1977-06-10
TR19262A (tr)	1978-09-19
SE7614389L (sv)	1977-06-23
FI60449B (fi)	1981-09-30
DE2657926B2 (de)	1978-06-08
FI60449C (fi)	1982-01-11
ES454866A1 (es)	1978-01-16
BR7608652A (pt)	1978-01-03
FI763646A7 (el)	1977-06-23
ZA767051B (en)	1977-10-26
NL7614167A (nl)	1977-06-24
DK145276B (da)	1982-10-18
DK145276C (da)	1983-03-07
IT1155243B (it)	1987-01-21
ATA948876A (de)	1979-03-15
NO146581C (no)	1982-10-27
US4148609A (en)	1979-04-10
GB1531530A (en)	1978-11-08
DK577376A (da)	1977-06-23
PT65994B (en)	1978-06-16
NO146581B (no)	1982-07-19
FR2336685A1 (fr)	1977-07-22

Legal Events

Date	Code	Title	Description
1992-08-31	PL	Patent ceased
2024-10-31	PL	Patent ceased

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Brown et al.	1981	Safranin O-stained antigen microagglutination test for detection of Brucella antibodies
FI79614B (fi)	1989-09-29	Testfoerpackning och foerfarande foer bestaemning av streptococcus a
KR100209072B1 (ko)	1999-07-15	숙신이미드함유 중합체로 생물학적 활성 시약을 제조하는 방법, 분석 요소 및 이것의 사용방법
SE443660B (sv)	1986-03-03	Forfarande och reagens for immunanalys med rf eller clq adsorberat till fast berare
Green	1967	Erythrocyte membrane sulfhydryl groups and Rh antingen activity
EP0328413B1 (en)	1994-08-24	Sodium decyl sulfate wash solution, test kit and method for the determination of an immunological ligand
US5919419A (en)	1999-07-06	Analyzer cuvette, method and diagnostic test kit for determination of analytes in whole blood samples
EP0344287B1 (en)	1995-08-16	Conservative whole blood sample preparation technique
NO177444B (no)	1995-06-06	Fremgangsmåte for immunometrisk bestemmelse av et antigen, samt utstyrspakke for slik bestemmelse
US4141965A (en)	1979-02-27	Assay of immune complexes
JPH01248061A (ja)	1989-10-03	試験キットおよび免疫リガンドの測定方法
JPS61228351A (ja)	1986-10-11	糞便中のヘモグロビンの検出方法
CH624772A5 (el)	1981-08-14
US7767436B2 (en)	2010-08-03	Reducing time to result for blood bank diagnostic testing
JP2553852B2 (ja)	1996-11-13	サンプル中の生物学的物質の免疫学的測定法
JPS59108959A (ja)	1984-06-23	ヒスタミン定量法
EP0280557B1 (en)	1993-09-08	Test kit, extraction device and method for the determination of streptococcus a antigen
Stone et al.	1961	Naturally occurring isoantibodies of the S blood group system in cattle
US4403040A (en)	1983-09-06	Diagnostic test for the detection of a specific tumor antigen with CoA-SPC
RU2169367C1 (ru)	2001-06-20	Способ определения активности эндотоксина (варианты)
RU2168175C1 (ru)	2001-05-27	Способ диагностики инфекций
Mattiasson et al.	1982	Partition Affinity Ligand Assay (PALA): Applications in the Analysis of Haptens, Macromolecules, and Cells
Bogner et al.	1989	Release of hemoglobin and potassium from human red blood cells treated with Triton X-100 under the critical micellar concentration