CH627000A5 - - Google Patents

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Info

Publication number: CH627000A5
Authority: CH; Switzerland
Prior art keywords: protein; approx; acetic acid; indicator; polypropylene glycol
Prior art date: 1975-03-12

Application number

CH296376A

Other languages

German (de)

English (en)

Inventor

Walter Dr Rer Nat Rittersdorf

Werner Dr Rer Nat Guethlein

Wolfgang Dr Rer Nat Werner

Hans-Georg Dr Rer Nat Rey

Peter Dr Rer Nat Rieckmann

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1975-03-12

Filing date

1976-03-10

Publication date

1981-12-15

1976-03-10 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1981-12-15 Publication of CH627000A5 publication Critical patent/CH627000A5/de

Links

QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 41
102000004169 proteins and genes Human genes 0.000 description 27
108090000623 proteins and genes Proteins 0.000 description 27
229920001451 polypropylene glycol Polymers 0.000 description 26
239000000243 solution Substances 0.000 description 20
229960000583 acetic acid Drugs 0.000 description 17
210000002700 urine Anatomy 0.000 description 16
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 15
LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 description 15
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 12
239000000872 buffer Substances 0.000 description 10
LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 description 10
239000012362 glacial acetic acid Substances 0.000 description 10
102000009027 Albumins Human genes 0.000 description 9
108010088751 Albumins Proteins 0.000 description 9
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
239000000203 mixture Substances 0.000 description 8
229960000948 quinine Drugs 0.000 description 8
235000001258 Cinchona calisaya Nutrition 0.000 description 7
238000006243 chemical reaction Methods 0.000 description 7
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 6
239000002585 base Substances 0.000 description 6
150000001875 compounds Chemical class 0.000 description 6
229910052757 nitrogen Inorganic materials 0.000 description 6
239000003795 chemical substances by application Substances 0.000 description 5
239000013078 crystal Substances 0.000 description 5
229940039227 diagnostic agent Drugs 0.000 description 5
239000000032 diagnostic agent Substances 0.000 description 5
125000006353 oxyethylene group Chemical group 0.000 description 5
239000000126 substance Substances 0.000 description 5
229920002176 Pluracol® Polymers 0.000 description 4
QPMIVFWZGPTDPN-UHFFFAOYSA-N Tetrabromophenol blue Chemical compound C1=C(Br)C(O)=C(Br)C=C1C1(C=2C=C(Br)C(O)=C(Br)C=2)C(C(Br)=C(Br)C(Br)=C2Br)=C2S(=O)(=O)O1 QPMIVFWZGPTDPN-UHFFFAOYSA-N 0.000 description 4
239000012928 buffer substance Substances 0.000 description 4
238000001514 detection method Methods 0.000 description 4
229920000151 polyglycol Polymers 0.000 description 4
239000010695 polyglycol Substances 0.000 description 4
LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 description 4
239000000080 wetting agent Substances 0.000 description 4
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
ZJCCRDAZUWHFQH-UHFFFAOYSA-N Trimethylolpropane Chemical compound CCC(CO)(CO)CO ZJCCRDAZUWHFQH-UHFFFAOYSA-N 0.000 description 3
239000002250 absorbent Substances 0.000 description 3
230000002745 absorbent Effects 0.000 description 3
239000007864 aqueous solution Substances 0.000 description 3
210000001124 body fluid Anatomy 0.000 description 3
239000010839 body fluid Substances 0.000 description 3
239000003153 chemical reaction reagent Substances 0.000 description 3
239000000460 chlorine Substances 0.000 description 3
229910052801 chlorine Inorganic materials 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
239000007793 ph indicator Substances 0.000 description 3
230000035945 sensitivity Effects 0.000 description 3
239000002904 solvent Substances 0.000 description 3
238000003756 stirring Methods 0.000 description 3
239000004094 surface-active agent Substances 0.000 description 3
BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
ISPYQTSUDJAMAB-UHFFFAOYSA-N 2-chlorophenol Chemical compound OC1=CC=CC=C1Cl ISPYQTSUDJAMAB-UHFFFAOYSA-N 0.000 description 2
QKICWELGRMTQCR-UHFFFAOYSA-N 4-[(7-chloroquinolin-4-yl)azaniumyl]pentyl-diethylazanium;dihydrogen phosphate Chemical compound OP(O)(O)=O.OP(O)(O)=O.ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 QKICWELGRMTQCR-UHFFFAOYSA-N 0.000 description 2
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
YASYEJJMZJALEJ-UHFFFAOYSA-N Citric acid monohydrate Chemical compound O.OC(=O)CC(O)(C(O)=O)CC(O)=O YASYEJJMZJALEJ-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 2
GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 description 2
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
239000002253 acid Substances 0.000 description 2
BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
229910021529 ammonia Inorganic materials 0.000 description 2
QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
125000004429 atom Chemical group 0.000 description 2
CNBGNNVCVSKAQZ-UHFFFAOYSA-N benzydamine Chemical compound C12=CC=CC=C2C(OCCCN(C)C)=NN1CC1=CC=CC=C1 CNBGNNVCVSKAQZ-UHFFFAOYSA-N 0.000 description 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 2
229910052794 bromium Inorganic materials 0.000 description 2
238000005660 chlorination reaction Methods 0.000 description 2
238000007654 immersion Methods 0.000 description 2
238000005470 impregnation Methods 0.000 description 2
239000001630 malic acid Substances 0.000 description 2
235000011090 malic acid Nutrition 0.000 description 2
238000000034 method Methods 0.000 description 2
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 2
SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 2
125000005702 oxyalkylene group Chemical group 0.000 description 2
229960001404 quinidine Drugs 0.000 description 2
238000001953 recrystallisation Methods 0.000 description 2
230000008961 swelling Effects 0.000 description 2
239000002562 thickening agent Substances 0.000 description 2
AFCLDQRTFFTBAP-UHFFFAOYSA-N 2,3,4,5-tetrachloro-6-(2,3,4,5-tetrachloro-6-sulfobenzoyl)oxycarbonylbenzenesulfonic acid Chemical compound OS(=O)(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C(=O)OC(=O)C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1S(O)(=O)=O AFCLDQRTFFTBAP-UHFFFAOYSA-N 0.000 description 1
RULKYXXCCZZKDZ-UHFFFAOYSA-N 2,3,4,5-tetrachlorophenol Chemical compound OC1=CC(Cl)=C(Cl)C(Cl)=C1Cl RULKYXXCCZZKDZ-UHFFFAOYSA-N 0.000 description 1
VADKRMSMGWJZCF-UHFFFAOYSA-N 2-bromophenol Chemical compound OC1=CC=CC=C1Br VADKRMSMGWJZCF-UHFFFAOYSA-N 0.000 description 1
GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
239000006173 Good's buffer Substances 0.000 description 1
229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
239000002841 Lewis acid Substances 0.000 description 1
ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000000654 additive Substances 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
239000003513 alkali Substances 0.000 description 1
150000001447 alkali salts Chemical class 0.000 description 1
150000003863 ammonium salts Chemical class 0.000 description 1
150000008064 anhydrides Chemical class 0.000 description 1
125000000129 anionic group Chemical group 0.000 description 1
239000003945 anionic surfactant Substances 0.000 description 1
239000010425 asbestos Substances 0.000 description 1
229960000333 benzydamine Drugs 0.000 description 1
230000000740 bleeding effect Effects 0.000 description 1
230000031709 bromination Effects 0.000 description 1
238000005893 bromination reaction Methods 0.000 description 1
239000003093 cationic surfactant Substances 0.000 description 1
125000001309 chloro group Chemical group Cl* 0.000 description 1
235000015165 citric acid Nutrition 0.000 description 1
229940096386 coconut alcohol Drugs 0.000 description 1
230000000536 complexating effect Effects 0.000 description 1
239000008139 complexing agent Substances 0.000 description 1
239000000470 constituent Substances 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000007547 defect Effects 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
238000009826 distribution Methods 0.000 description 1
239000000975 dye Substances 0.000 description 1
230000000694 effects Effects 0.000 description 1
WSTZPWUPYWHZRR-UHFFFAOYSA-N ethene;2-ethyl-2-(hydroxymethyl)propane-1,3-diol Chemical group C=C.CCC(CO)(CO)CO WSTZPWUPYWHZRR-UHFFFAOYSA-N 0.000 description 1
125000004494 ethyl ester group Chemical group 0.000 description 1
230000029142 excretion Effects 0.000 description 1
150000002191 fatty alcohols Chemical class 0.000 description 1
239000003337 fertilizer Substances 0.000 description 1
239000000835 fiber Substances 0.000 description 1
239000012530 fluid Substances 0.000 description 1
125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
239000001863 hydroxypropyl cellulose Substances 0.000 description 1
235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
239000012442 inert solvent Substances 0.000 description 1
229910052920 inorganic sulfate Inorganic materials 0.000 description 1
208000017169 kidney disease Diseases 0.000 description 1
150000007517 lewis acids Chemical class 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
235000019341 magnesium sulphate Nutrition 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
229940126601 medicinal product Drugs 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
HWPKGOGLCKPRLZ-UHFFFAOYSA-M monosodium citrate Chemical compound [Na+].OC(=O)CC(O)(C([O-])=O)CC(O)=O HWPKGOGLCKPRLZ-UHFFFAOYSA-M 0.000 description 1
235000018342 monosodium citrate Nutrition 0.000 description 1
239000002524 monosodium citrate Substances 0.000 description 1
239000003921 oil Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
150000002989 phenols Chemical class 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920002635 polyurethane Polymers 0.000 description 1
239000004814 polyurethane Substances 0.000 description 1
230000001376 precipitating effect Effects 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000002331 protein detection Methods 0.000 description 1
239000002994 raw material Substances 0.000 description 1
229910052895 riebeckite Inorganic materials 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
238000010186 staining Methods 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
230000003313 weakening effect Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
- C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6827—Total protein determination, e.g. albumin in urine
- G01N33/6839—Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Urology & Nephrology (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Hematology (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Bioinformatics & Computational Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Microbiology (AREA)
Food Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

CH296376A 1975-03-12 1976-03-10 CH627000A5 (cs)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2510633A DE2510633C3 (de)	1975-03-12	1975-03-12	Diagnostisches Mittel zum Nachweis von Eiweiß in Körperflüssigkeiten und dafür geeignete Indikatorfarbstoffe

Publications (1)

Publication Number	Publication Date
CH627000A5 true CH627000A5 (cs)	1981-12-15

Family

ID=5941061

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH296376A CH627000A5 (cs)	1975-03-12	1976-03-10

Country Status (25)

Country	Link
US (2)	US4013416A (cs)
JP (1)	JPS5278866A (cs)
AT (1)	AT349153B (cs)
AU (1)	AU501932B2 (cs)
BE (1)	BE839363A (cs)
CA (1)	CA1055824A (cs)
CH (1)	CH627000A5 (cs)
CS (1)	CS190526B2 (cs)
DD (2)	DD125021A5 (cs)
DE (1)	DE2510633C3 (cs)
DK (1)	DK144443C (cs)
ES (1)	ES445808A1 (cs)
FI (1)	FI59678C (cs)
FR (1)	FR2304084A1 (cs)
GB (2)	GB1487718A (cs)
HU (1)	HU172450B (cs)
IE (3)	IE42507L (cs)
IL (1)	IL49167A (cs)
IT (1)	IT1056947B (cs)
LU (1)	LU74519A1 (cs)
NL (1)	NL164966C (cs)
PL (1)	PL103510B1 (cs)
SE (1)	SE423754B (cs)
SU (2)	SU633501A3 (cs)
YU (1)	YU59476A (cs)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5513814A (en) *	1978-07-12	1980-01-31	Mitsui Toatsu Chem Inc	Inspecting method for albumin
US4654309A (en) *	1980-12-19	1987-03-31	Minnesota Mining And Manufacturing Co.	Test method and article for estimating the concentration of free acid in liquid
AU547596B2 (en) *	1980-12-19	1985-10-24	Minnesota Mining And Manufacturing Company	Test method and article for estimating the concentration of free acid in liquid
US4542750A (en) *	1982-08-13	1985-09-24	Primary Diagnostic Systems, Inc.	Non-invasive method for diagnosing incipient or developed cancer tissue
US4568647A (en) *	1983-10-11	1986-02-04	Eastman Kodak Company	Method and element for albumin assay
DE3345748A1 (de) *	1983-12-17	1985-08-29	Boehringer Mannheim Gmbh, 6800 Mannheim	Phenolsulfonphthaleinyl-ss-d-galactoside, verfahren zu deren herstellung sowie deren verwendung zur bestimmung der ss-d-galactosidase
US5183742A (en) *	1984-02-24	1993-02-02	Dai Nippon Insatsu Kabushiki Kaisha	Test device for detecting glucose, protein urobilinogen, and/or occult blood in body fluids and/or determining the PH thereof
EP0287745B1 (en) *	1987-04-22	1991-11-13	Schiapparelli Biosystems, Inc.	Method for the determination of albumin in biological fluids
CA1320420C (en) *	1988-03-25	1993-07-20	Dominique Thoraval	Paper chemical agent detectors
US5194390A (en) *	1988-07-05	1993-03-16	Miles Inc.	Composition for the assay of albumin
DE3823151C2 (de) *	1988-07-08	1997-07-10	Boehringer Mannheim Gmbh	Verfahren zur Bestimmung der Ionenstärke oder des spezifischen Gewichts von wäßrigen Flüssigkeiten
US5077222A (en) *	1988-09-30	1991-12-31	Miles Inc.	Method for assaying for proteins using a dual indicator reagent composition
US5049358A (en) *	1988-09-30	1991-09-17	Miles Inc.	Composition and test device for assaying for proteins
JPH0752198B2 (ja) *	1989-08-30	1995-06-05	マイルス・インコーポレーテッド	変色を示す組成物、アルブミンの存在及び／又は濃度の測定方法及び検出具
US5264589A (en) *	1991-06-06	1993-11-23	Miles Inc.	Merocyanine protein error indicators
ATE143144T1 (de) *	1991-06-06	1996-10-15	Bayer Ag	Teststreifen mit merocyanin und nitro- oder nitroso-substituierten polyhalogenierten phenolsulfonphthaleinen als protein-indikatoren
US5187104A (en) *	1991-06-06	1993-02-16	Miles Inc.	Nitro or nitroso substituted polyhalogenated phenolsulfonephthaleins as protein indicators in biological samples
US5326707A (en) *	1991-11-29	1994-07-05	Miles Inc.	Composition and device for urinary protein assay and method of using the same
US5424215A (en) *	1994-02-07	1995-06-13	Miles Inc.	Assay for the determination of protein in a biological sample
US5593895A (en) *	1995-04-27	1997-01-14	Bayer Corporation	Method for the detection of protein in urine
US6551791B1 (en)	1995-12-21	2003-04-22	University Of Florida	Rapid diagnostic method for distinguishing allergies and infections and nasal secretion collection unit
US5910421A (en) *	1995-12-21	1999-06-08	University Of Florida	Rapid diagnostic method for distinguishing allergies and infections
KR100318552B1 (ko) *	1998-12-24	2002-09-05	한국과학기술연구원	간질환관련표식물질의검출용스트립
EP1039299B1 (en) *	1999-03-24	2004-11-17	JohnsonDiversey, Inc.	A method of detecting protein and a kit using the same
DE60015832T2 (de)	1999-03-24	2005-10-27	JohnsonDiversey, Inc., Sturtevant	Verfahren zum Nachweis von Protein und Kit dafür
EP1548443A4 (en) *	2002-08-09	2006-09-06	Arkray Inc	TEST MEMBER FOR PROTEIN ASSAY AND METHOD OF MANUFACTURING THE SAME
ATE525656T1 (de)	2004-01-23	2011-10-15	Arkray Inc	Proteinmessverfahren
US7727206B2 (en) *	2005-12-27	2010-06-01	Gorres Geoffrey H	Device for monitoring a patient for a urinary tract infection
US8012761B2 (en) *	2006-12-14	2011-09-06	Kimberly-Clark Worldwide, Inc.	Detection of formaldehyde in urine samples
US7846383B2 (en) *	2006-12-15	2010-12-07	Kimberly-Clark Worldwide, Inc.	Lateral flow assay device and absorbent article containing same
GB0808557D0 (en)	2008-05-13	2008-06-18	3M Innovative Properties Co	Sampling devices and methods of use
GB2460069A (en) *	2008-05-15	2009-11-18	Snell & Wilcox Ltd	Sampling conversion between formats in digital image processing
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1975
- 1975-03-12 DE DE2510633A patent/DE2510633C3/de not_active Expired
1976
- 1976-02-23 SE SE7602134A patent/SE423754B/xx not_active IP Right Cessation
- 1976-02-26 DD DD191553A patent/DD125021A5/xx unknown
- 1976-02-26 DD DD7600198424A patent/DD129788A5/xx unknown
- 1976-02-26 US US05/661,687 patent/US4013416A/en not_active Expired - Lifetime
- 1976-03-05 CS CS761458A patent/CS190526B2/cs unknown
- 1976-03-05 ES ES445808A patent/ES445808A1/es not_active Expired
- 1976-03-05 FI FI760578A patent/FI59678C/fi not_active IP Right Cessation
- 1976-03-05 SU SU762328363A patent/SU633501A3/ru active
- 1976-03-05 IL IL49167A patent/IL49167A/xx unknown
- 1976-03-08 YU YU00594/76A patent/YU59476A/xx unknown
- 1976-03-08 IT IT20968/76A patent/IT1056947B/it active
- 1976-03-09 NL NL7602442.A patent/NL164966C/xx not_active IP Right Cessation
- 1976-03-09 BE BE164993A patent/BE839363A/xx not_active IP Right Cessation
- 1976-03-10 HU HU76BO00001602A patent/HU172450B/hu unknown
- 1976-03-10 DK DK103276A patent/DK144443C/da not_active IP Right Cessation
- 1976-03-10 CH CH296376A patent/CH627000A5/de not_active IP Right Cessation
- 1976-03-10 LU LU74519A patent/LU74519A1/xx unknown
- 1976-03-11 IE IE772561A patent/IE42507L/xx unknown
- 1976-03-11 AU AU11895/76A patent/AU501932B2/en not_active Expired
- 1976-03-11 GB GB27421/76A patent/GB1487718A/en not_active Expired
- 1976-03-11 PL PL1976187846A patent/PL103510B1/pl unknown
- 1976-03-11 IE IE504/76A patent/IE42506B1/en unknown
- 1976-03-11 AT AT180576A patent/AT349153B/de not_active IP Right Cessation
- 1976-03-11 FR FR7606937A patent/FR2304084A1/fr active Granted
- 1976-03-11 GB GB9734/76A patent/GB1487717A/en not_active Expired
- 1976-03-11 IE IE2561/77A patent/IE42507B1/en unknown
- 1976-03-12 JP JP51027019A patent/JPS5278866A/ja active Granted
- 1976-03-12 CA CA248,333A patent/CA1055824A/en not_active Expired
- 1976-11-10 US US05/740,462 patent/US4260777A/en not_active Expired - Lifetime
1977
- 1977-05-23 SU SU772482007A patent/SU625610A3/ru active

Also Published As

Publication number	Publication date
US4260777A (en)	1981-04-07
IE42507B1 (en)	1980-08-27
FI760578A7 (cs)	1976-09-13
IL49167A0 (en)	1976-05-31
IL49167A (en)	1978-08-31
DK103276A (da)	1976-09-13
IE42507L (en)	1976-09-12
HU172450B (hu)	1978-09-28
GB1487717A (en)	1977-10-05
CA1055824A (en)	1979-06-05
DK144443C (da)	1982-08-23
US4013416A (en)	1977-03-22
AU1189576A (en)	1977-09-15
JPS5278866A (en)	1977-07-02
CS190526B2 (en)	1979-05-31
AU501932B2 (en)	1979-07-05
JPS5751627B2 (cs)	1982-11-02
IE42506B1 (en)	1980-08-27
SE423754B (sv)	1982-05-24
IT1056947B (it)	1982-02-20
YU59476A (en)	1988-10-31
IE42506L (en)	1976-09-12
ATA180576A (de)	1978-08-15
DE2510633C3 (de)	1978-07-13
BE839363A (fr)	1976-09-09
SU633501A3 (ru)	1978-11-15
PL103510B1 (pl)	1979-06-30
DD125021A5 (cs)	1977-03-23
LU74519A1 (cs)	1976-09-01
DE2510633A1 (de)	1976-09-16
AT349153B (de)	1979-03-26
FR2304084A1 (fr)	1976-10-08
SU625610A3 (ru)	1978-09-25
FR2304084B1 (cs)	1981-06-26
SE7602134L (sv)	1976-09-13
DE2510633B2 (de)	1977-11-10
GB1487718A (en)	1977-10-05
FI59678C (fi)	1981-09-10
NL164966C (nl)	1981-02-16
FI59678B (fi)	1981-05-29
NL7602442A (nl)	1976-09-14
DD129788A5 (de)	1978-02-08
NL164966B (nl)	1980-09-15
ES445808A1 (es)	1977-06-01
DK144443B (da)	1982-03-08

Legal Events

Date	Code	Title	Description
1996-03-29	PL	Patent ceased

Publication	Publication Date	Title
CH627000A5 (cs)	1981-12-15
EP0226767B1 (de)	1992-09-16	Transparentes Teststreifensystem
DE2235152B1 (de)	1974-01-10	Diagnostisches mittel zum nachweis von blut und anderen peroxidatisch wirksamen substanzen in koerperfluessigkeiten
EP0461392A2 (de)	1991-12-18	Testträger zur Bestimmung von Ionen
DE7611756U1 (de)	1976-11-25	Indikationsstreifen zur kennzeichnung von sterilisiervorgaengen
DE2644501B2 (de)	1979-04-12	Prüfmittel zur Bestimmung von Bilirubin in Urin
DE2326935C3 (de)	1979-04-19	Verfahren zur Herstellung von Lignin-Addukten mit blockierten Hydroxylgruppen und diese Addukte enthaltende Farbstoffmasse
DE2716061A1 (de)	1978-10-19	Guajaconsaeure a, verfahren zu ihrer herstellung und diese substanz enthaltende diagnostische mittel
DE2130559C3 (de)	1973-11-22	Diagnostisches Mittel zum Nach weis von Urobihnogen
DE1941370A1 (de)	1971-03-04	Diagnostisches Mittel zum Nachweis von Nitrit und nitritbildenden Bakterien in Koerperfluessigkeiten
DE69223851T2 (de)	1998-04-16	Nitro- oder Nitroso-substituierte polyhalogenierte Phenolsulfonphtaleine
DE3225331A1 (de)	1984-01-12	Verfahren zur bestimmung von direktem und gesamt-bilirubin sowie hierfuer geeignetes reagens
DE1767931A1 (de)	1972-08-10	Verfahren und diagnostisches Mittel zum Nachweis von Urobilinogen-Koerpern
EP0349934A2 (de)	1990-01-10	Verfahren zur Bestimmung der Ionenstärke oder des spezifischen Gewichts von Wässrigen Flüssigkeiten
DE2240471A1 (de)	1974-03-14	Diagnostisches mittel zum nachweis von bilirubin
DE69625024T2 (de)	2003-04-17	Verfahren zum Nachweis von Protein im Harn
DE834237C (de)	1952-03-17	Verfahren zur Herstellung nicht staubender wasserloeslicher organischer Farbstoffpraeparate
DE2521402C3 (de)	1979-07-26	Diagnostisches Mittel zum Nachweis von Urobilinogen
DE2030720C3 (de)	1978-09-21	Diagnostische Zusammensetzung zum Nachweis von durch Mikroorganismen aus Nitrat gebildetem Nitrit
DE69019810T2 (de)	1995-11-30	Verfahren zur optischen Bestimmung von Bilirubin und Reagenz dafür.
DE69114336T2 (de)	1996-04-18	Trockenes analytisches Element zur Bestimmung von Salicylat.
DE1447024C3 (de)	1978-03-09	Verfahren zur Herstellung eines lichtempfindlichen Aufzeichnungsmaterials und dessen Verwendung
EP0009164A1 (de)	1980-04-02	Diagnostisches Mittel und dessen Verwendung zum Nachweis von Urobilinogen
DE2728236B2 (de)	1980-09-18	Stabilisierte diagnostische Zubereitung zum Nachweis von Urobilinogen
DE4015592A1 (de)	1991-11-21	Verfahren zur bestimmung eines ions mit erhoehter empfindlichkeit, verwendung hierfuer geeigneter substanzen und entsprechendes mittel