CH646069A5 - Verfahren zur isolierung eines materials aus einer loesung. - Google Patents
Verfahren zur isolierung eines materials aus einer loesung. Download PDFInfo
- Publication number
- CH646069A5 CH646069A5 CH289580A CH289580A CH646069A5 CH 646069 A5 CH646069 A5 CH 646069A5 CH 289580 A CH289580 A CH 289580A CH 289580 A CH289580 A CH 289580A CH 646069 A5 CH646069 A5 CH 646069A5
- Authority
- CH
- Switzerland
- Prior art keywords
- solution
- nicotinamide
- shear force
- solid
- liquid
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 22
- 239000000463 material Substances 0.000 title claims description 17
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 40
- 239000000243 solution Substances 0.000 claims description 24
- 235000005152 nicotinamide Nutrition 0.000 claims description 19
- 239000011570 nicotinamide Substances 0.000 claims description 19
- 229960003966 nicotinamide Drugs 0.000 claims description 19
- 238000001816 cooling Methods 0.000 claims description 18
- 239000002002 slurry Substances 0.000 claims description 14
- 239000007787 solid Substances 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- 239000007864 aqueous solution Substances 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000006193 liquid solution Substances 0.000 claims description 2
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 28
- 235000001968 nicotinic acid Nutrition 0.000 description 14
- 239000011664 nicotinic acid Substances 0.000 description 14
- 229960003512 nicotinic acid Drugs 0.000 description 14
- 239000013078 crystal Substances 0.000 description 12
- 239000000203 mixture Substances 0.000 description 12
- 238000001914 filtration Methods 0.000 description 8
- ONJIBHRZSUEBDS-UHFFFAOYSA-N azane;pyridine-3-carboxylic acid Chemical compound [NH4+].[O-]C(=O)C1=CC=CN=C1 ONJIBHRZSUEBDS-UHFFFAOYSA-N 0.000 description 5
- 239000012452 mother liquor Substances 0.000 description 5
- 239000002244 precipitate Substances 0.000 description 5
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 4
- 238000002425 crystallisation Methods 0.000 description 4
- 230000008025 crystallization Effects 0.000 description 4
- 238000001556 precipitation Methods 0.000 description 4
- 238000005406 washing Methods 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 238000010899 nucleation Methods 0.000 description 2
- 230000006911 nucleation Effects 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 238000010583 slow cooling Methods 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 229960002715 nicotine Drugs 0.000 description 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 description 1
- -1 nicotine nitrile Chemical class 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 239000012047 saturated solution Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3009179A | 1979-04-16 | 1979-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH646069A5 true CH646069A5 (de) | 1984-11-15 |
Family
ID=21852450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH289580A CH646069A5 (de) | 1979-04-16 | 1980-04-15 | Verfahren zur isolierung eines materials aus einer loesung. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5913881B2 (es) |
| CH (1) | CH646069A5 (es) |
| DE (1) | DE3014160A1 (es) |
| ES (1) | ES8301470A1 (es) |
| GB (1) | GB2050190B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10218106A1 (de) * | 2002-04-23 | 2003-11-20 | Jenapharm Gmbh | Verfahren zum Herstellen von Kristallen von Arzneimittelwirkstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen |
| DE10218110A1 (de) * | 2002-04-23 | 2003-11-20 | Jenapharm Gmbh | Verfahren zum Herstellen von Kristallen von Arzneimittelhilfsstoffen, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen |
| TW201402153A (zh) | 2012-04-04 | 2014-01-16 | Lonza Ag | 菸鹼醯胺粉末和其製備方法及裝置 |
-
1980
- 1980-04-12 DE DE19803014160 patent/DE3014160A1/de not_active Ceased
- 1980-04-14 GB GB8012222A patent/GB2050190B/en not_active Expired
- 1980-04-15 JP JP5023480A patent/JPS5913881B2/ja not_active Expired
- 1980-04-15 CH CH289580A patent/CH646069A5/de not_active IP Right Cessation
- 1980-04-15 ES ES490585A patent/ES8301470A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES490585A0 (es) | 1982-12-01 |
| JPS55139801A (en) | 1980-11-01 |
| JPS5913881B2 (ja) | 1984-04-02 |
| GB2050190A (en) | 1981-01-07 |
| DE3014160A1 (de) | 1980-10-30 |
| ES8301470A1 (es) | 1982-12-01 |
| GB2050190B (en) | 1983-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69127485T2 (de) | Verfahren zur selektiven Herstellung von Hydratkristallen | |
| DE69230058T2 (de) | Reinigung von organischen Verbindungen durch Kristallisierung | |
| DE2803590C2 (de) | Verfahren zum Reinigen von Natriumhexafluorosilikat | |
| DE2060683C2 (de) | Verfahren zur Isolierung von reinem kubischen oder hartem hexagonalen Bornitrid | |
| DE3237653C2 (de) | Verfahren zur Herstellung von Harnstoff | |
| DE69322820T2 (de) | Verfahren zur Kristallisierung von Aspartam | |
| DE1021831B (de) | Verfahren zur Herstellung von reinem kristallisiertem Ammoniumbifluorid aus Fluokieselsaeure und Ammoniak | |
| DE2915396A1 (de) | Verfahren zur herstellung von yttriumoxid mit besonders grossen partikeln | |
| DE2908762A1 (de) | Calciumhypochlorit-dihydrat, verfahren zu seiner herstellung und seine verwendung | |
| DE3878580T2 (de) | Verfahren zur herstellung von kristallinen explosivstoffen. | |
| DE3014160A1 (de) | Kristallisationsverfahren | |
| DE706617C (de) | Verfahren zur Herstellung von Pentaerythrit | |
| DE1542611B2 (de) | Kontinuierliches Verfahren zur Herstellung von Phosphorsäure und Calciumsulfatdihydrat | |
| DE953977C (de) | Verfahren zur Gewinnung von reinen Nitraten aus salpetersauren Loesungen von Calciumphosphaten | |
| DE2152550B2 (de) | Verfahren zur Herstellung eines vorwiegend Biuret enthaltenden Gemisches von Autokondensationsprodukten des Harnstoffes | |
| DE677966C (de) | Aufschliessen von Phosphaten | |
| DE2530859C2 (de) | Verfahren zur Trennung von m- oder p-Kresol | |
| DE2740403C2 (es) | ||
| EP0100865B1 (de) | Verfahren zur Herstellung einer hydrolysierbaren Titanylsulfatlösung | |
| DE945281C (de) | Verfahren zur Abtrennung von festem Paraffin aus paraffinhaltigen OElen, insbesondere fuer die Gewinnung von Paraffinkonzentraten durch Flotation | |
| DE2909420A1 (de) | Verfahren zur behandlung einer langkettige dibasische fettsaeuren enthaltenden fermentationsbruehe | |
| DE714069C (de) | Verfahren zur Herstellung von kristallisierter Hydratdextrose | |
| DE2215590C3 (de) | Verfahren zur Herstellung von aus gesonderten Teilchen bestehenden und weniger als 1,5-Gew.-Prozent adsorptiv gebundene Feuchtigkeit enthaltenden trockenen festen anorganischen und organischen Verbindungen und/oder Verbindungsgemischen | |
| DE612162C (de) | Verfahren zur Gewinnung von reiner Xylose | |
| DE2946614C2 (es) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased | ||
| PL | Patent ceased |