CH85680A - Process for the preparation of a therapeutically valuable derivative of p-aminophenol. - Google Patents

Process for the preparation of a therapeutically valuable derivative of p-aminophenol.

Info

Publication number
CH85680A
CH85680A CH85680DA CH85680A CH 85680 A CH85680 A CH 85680A CH 85680D A CH85680D A CH 85680DA CH 85680 A CH85680 A CH 85680A
Authority
CH
Switzerland
Prior art keywords
aminophenol
preparation
therapeutically valuable
derivative
valuable derivative
Prior art date
Application number
Other languages
German (de)
Inventor
Gesellschaft Fuer Chemis Basel
Original Assignee
Chem Ind Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Ind Basel filed Critical Chem Ind Basel
Publication of CH85680A publication Critical patent/CH85680A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Description

         

  Verfahren zur Darstellung eines therapeutisch     wertvollen    Derivates des     p-Aminophenols.       Es wurde gefunden, dass man zu dem in  der Patentschrift Nr. 78043 beschriebenen       p-Formylamidophenolallylätliei-    auch gelangen  kann, wenn man     Formal-p-aminophenol    mit       allylierenden    Mitteln behandelt.  



  <I>Beispiel</I>  157 Teile     Formal-p-aminoplienol    werden  in 200 Teilen Alkohol gelöst und mit 121  Teilen     Allylbromid    versetzt. Unter Kochen  am     Rückflusse    gibt man in mehreren Por  tionen 56 Teile     Ätzkali    in 200 Teilen Alkohol  gelöst hinzu. Nach zwei Stunden filtriert  man vom Bromkali ab und verdampft den  Alkohol bis auf einen kleinen Teil. Das zu  rückbleibende Öl erstarrt beim Eingiessen in  Wasser. Man kristallisiert aus Wasser um    und erhält den     Formyl-p-aminophenolallyl-          äther    in weissen Blättchen vom Schmelz  punkte 56  .  



  Statt     Allylbromid    können andere     Ally-          lierungsmittel,    zum Beispiel andere     Allylhalo-          genide.,    verwendet werden.



  Process for the preparation of a therapeutically valuable derivative of p-aminophenol. It has been found that the p-Formylamidophenolallylätliei- described in Patent Specification No. 78043 can also be reached by treating formal-p-aminophenol with allylating agents.



  <I> Example </I> 157 parts of formal-p-aminoplienol are dissolved in 200 parts of alcohol and 121 parts of allyl bromide are added. While refluxing, 56 parts of caustic potash dissolved in 200 parts of alcohol are added in several portions. After two hours, the potassium bromide is filtered off and the alcohol is evaporated except for a small part. The oil that remains solidifies when it is poured into water. It is recrystallized from water and the formyl-p-aminophenol allyl ether is obtained in white flakes with a melting point of 56.



  Instead of allyl bromide, other allylating agents, for example other allyl halides, can be used.

Claims (1)

PATENTANSPRUCH: Verfahren zur Darstellung eines thera peutisch wertvollen Derivates des p-Amino- phenols, dadurch gekennzeichnet, dass man Foi-myl-p-aminophenol mit allylierenden Mit teln behandelt. PATENT CLAIM: Process for the preparation of a therapeutically valuable derivative of p-aminophenol, characterized in that foi-myl-p-aminophenol is treated with allylating agents.
CH85680D 1917-11-17 1917-11-17 Process for the preparation of a therapeutically valuable derivative of p-aminophenol. CH85680A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH85680T 1917-11-17
CH76619T 1917-11-17

Publications (1)

Publication Number Publication Date
CH85680A true CH85680A (en) 1920-07-01

Family

ID=25701877

Family Applications (1)

Application Number Title Priority Date Filing Date
CH85680D CH85680A (en) 1917-11-17 1917-11-17 Process for the preparation of a therapeutically valuable derivative of p-aminophenol.

Country Status (1)

Country Link
CH (1) CH85680A (en)

Similar Documents

Publication Publication Date Title
CH85680A (en) Process for the preparation of a therapeutically valuable derivative of p-aminophenol.
CH85679A (en) Process for the preparation of a therapeutically valuable derivative of p-aminophenol.
AT52846B (en) Process for the preparation of bromine diethyl acetylurea.
DE332204C (en) Process for the preparation of acyl derivatives of a p-aminophenol ether
DE503920C (en) Process for the preparation of aminopyridines iodinated in the 5-position from the chloroiodine compounds of 2-aminopyridine and its derivatives
AT153199B (en) Process for the preparation of amino alcohols.
CH85678A (en) Process for the preparation of a therapeutically valuable derivative of p-aminophenol.
AT67948B (en) Process for the preparation of homologues and substitution products of 2-piperonylquinoline-4-carboxylic acid.
AT60779B (en) Method for sweating paraffin and the like.
AT210563B (en) Process for the production of a new therapeutically valuable calcium salt
DE360689C (en) Process for the preparation of a derivative of Phenylaethylhydantoin
CH96608A (en) Process for the preparation of an acridine derivative.
CH187013A (en) Process for the preparation of a cyclic ketone.
CH150823A (en) Process for the preparation of a derivative of phenylethylamine.
CH306508A (en) Process for the preparation of 2-cyclopentenyl acetic acid hydrazide.
CH94626A (en) Process for the preparation of an acridine derivative.
CH167957A (en) Process for the preparation of an oxy fatty acid derivative.
CH91107A (en) Process for the preparation of a dioxynaphtoylbenzoic acid ester.
CH96606A (en) Process for the preparation of a basic derivative of p-aminophenol ethyl ether.
CH208533A (en) Process for the preparation of 4-oxybenzthiazole.
CH102142A (en) Process for the preparation of an aminobenzoyl derivative of 2-methyl-4-diethylamino-pentanol-5.
CH176155A (en) Process for the preparation of 2-ethoxy-5-propionyl-aminopyridine.
CH168032A (en) Process for the preparation of a therapeutically valuable derivative of veratrum acid.
CH187011A (en) Process for the preparation of a cyclic ketone.
CH91106A (en) Process for the preparation of a dioxynaphtoylbenzoic acid ester.