CL2007003811A1 - Inhibidores de proteasa no naturales del tipo de kunitz que tienen entre 56-60 aminoacidos; acido nucleico que codifica un inhibidor de proteasa no natural; uso de dicho inhibidor para tratamiento de hemorragias. - Google Patents
Inhibidores de proteasa no naturales del tipo de kunitz que tienen entre 56-60 aminoacidos; acido nucleico que codifica un inhibidor de proteasa no natural; uso de dicho inhibidor para tratamiento de hemorragias.Info
- Publication number
- CL2007003811A1 CL2007003811A1 CL200703811A CL2007003811A CL2007003811A1 CL 2007003811 A1 CL2007003811 A1 CL 2007003811A1 CL 200703811 A CL200703811 A CL 200703811A CL 2007003811 A CL2007003811 A CL 2007003811A CL 2007003811 A1 CL2007003811 A1 CL 2007003811A1
- Authority
- CL
- Chile
- Prior art keywords
- inhibitor
- natural
- hemorragies
- proteasa
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8114—Kunitz type inhibitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1031—Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Diabetes (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06026813 | 2006-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007003811A1 true CL2007003811A1 (es) | 2008-07-04 |
Family
ID=39204781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200703811A CL2007003811A1 (es) | 2006-12-22 | 2007-12-21 | Inhibidores de proteasa no naturales del tipo de kunitz que tienen entre 56-60 aminoacidos; acido nucleico que codifica un inhibidor de proteasa no natural; uso de dicho inhibidor para tratamiento de hemorragias. |
Country Status (7)
| Country | Link |
|---|---|
| AR (1) | AR064616A1 (es) |
| CL (1) | CL2007003811A1 (es) |
| PA (1) | PA8764101A1 (es) |
| PE (1) | PE20081648A1 (es) |
| TW (1) | TW200846356A (es) |
| UY (1) | UY30818A1 (es) |
| WO (1) | WO2008077478A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012275295B2 (en) * | 2011-06-28 | 2016-11-10 | Inhibrx, Lp | WAP domain fusion polypeptides and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99585A0 (en) * | 1990-10-01 | 1992-08-18 | Novo Nordisk As | Aprotinin analogues,their production and pharmaceutical compositions containing them |
| AU1581692A (en) * | 1991-03-01 | 1992-10-06 | Protein Engineering Corporation | Inhibitors of human neutrophil elastase and human cathepsin g |
| WO1995021601A2 (en) * | 1994-01-11 | 1995-08-17 | Protein Engineering Corporation | Kallikrein-inhibiting 'kunitz domain' proteins and analogues thereof |
| US5589359A (en) * | 1994-08-05 | 1996-12-31 | Chiron Corporation | Chimeric proteins |
| JP3469584B2 (ja) * | 1996-03-11 | 2003-11-25 | バイエル コーポレイション | ヒト ビクニン |
| DE19629982A1 (de) * | 1996-07-25 | 1998-01-29 | Bayer Ag | Aprotinin-Varianten mit verbesserten Eigenschaften |
| JP2002543147A (ja) * | 1999-04-29 | 2002-12-17 | ノボ ノルディスク アクティーゼルスカブ | ブラジキニン放出の阻害におけるヘパリン結合アンタゴニストの使用 |
| CN101395274A (zh) * | 2006-03-08 | 2009-03-25 | 拜耳医药保健股份公司 | 嵌合Kunitz结构域及其用途 |
-
2007
- 2007-12-11 WO PCT/EP2007/010796 patent/WO2008077478A1/en not_active Ceased
- 2007-12-20 AR ARP070105781A patent/AR064616A1/es unknown
- 2007-12-20 UY UY30818A patent/UY30818A1/es not_active Application Discontinuation
- 2007-12-21 PA PA20078764101A patent/PA8764101A1/es unknown
- 2007-12-21 TW TW096149116A patent/TW200846356A/zh unknown
- 2007-12-21 CL CL200703811A patent/CL2007003811A1/es unknown
-
2008
- 2008-01-02 PE PE2008000073A patent/PE20081648A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PA8764101A1 (es) | 2009-09-17 |
| WO2008077478A1 (en) | 2008-07-03 |
| AR064616A1 (es) | 2009-04-15 |
| UY30818A1 (es) | 2008-07-31 |
| TW200846356A (en) | 2008-12-01 |
| PE20081648A1 (es) | 2009-01-01 |
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