CL2009000609A1 - Triphasic combined pharmaceutical product with 24 dosage units, where the amount of drospirenone during the three phases is constant and the amount of 17 beta-estradiol increases from 1 mg to 2 mg, in addition to 4 dosage units of placebo or without units of dosage; pharmaceutical kit. - Google Patents
Triphasic combined pharmaceutical product with 24 dosage units, where the amount of drospirenone during the three phases is constant and the amount of 17 beta-estradiol increases from 1 mg to 2 mg, in addition to 4 dosage units of placebo or without units of dosage; pharmaceutical kit.Info
- Publication number
- CL2009000609A1 CL2009000609A1 CL2009000609A CL2009000609A CL2009000609A1 CL 2009000609 A1 CL2009000609 A1 CL 2009000609A1 CL 2009000609 A CL2009000609 A CL 2009000609A CL 2009000609 A CL2009000609 A CL 2009000609A CL 2009000609 A1 CL2009000609 A1 CL 2009000609A1
- Authority
- CL
- Chile
- Prior art keywords
- dosage
- units
- amount
- dosage units
- triphasic
- Prior art date
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title abstract 4
- 229960005309 estradiol Drugs 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 229940127557 pharmaceutical product Drugs 0.000 title abstract 2
- METQSPRSQINEEU-UHFFFAOYSA-N dihydrospirorenone Natural products CC12CCC(C3(CCC(=O)C=C3C3CC33)C)C3C1C1CC1C21CCC(=O)O1 METQSPRSQINEEU-UHFFFAOYSA-N 0.000 title 1
- METQSPRSQINEEU-HXCATZOESA-N drospirenone Chemical compound C([C@]12[C@H]3C[C@H]3[C@H]3[C@H]4[C@@H]([C@]5(CCC(=O)C=C5[C@@H]5C[C@@H]54)C)CC[C@@]31C)CC(=O)O2 METQSPRSQINEEU-HXCATZOESA-N 0.000 title 1
- 229960004845 drospirenone Drugs 0.000 title 1
- 239000000902 placebo Substances 0.000 title 1
- 229940068196 placebo Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Producto farmacéutico que comprende drospiredona y 17beta-estradiol, combinación que contiene este producto y kit que contiene esta combinación.Pharmaceutical product comprising drospiredone and 17beta-estradiol, combination contained in this product and kit containing this combination.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3528508P | 2008-03-10 | 2008-03-10 | |
| US3612908P | 2008-03-13 | 2008-03-13 | |
| US4041008P | 2008-03-28 | 2008-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2009000609A1 true CL2009000609A1 (en) | 2010-03-26 |
Family
ID=41065592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2009000609A CL2009000609A1 (en) | 2008-03-10 | 2009-03-13 | Triphasic combined pharmaceutical product with 24 dosage units, where the amount of drospirenone during the three phases is constant and the amount of 17 beta-estradiol increases from 1 mg to 2 mg, in addition to 4 dosage units of placebo or without units of dosage; pharmaceutical kit. |
Country Status (3)
| Country | Link |
|---|---|
| CL (1) | CL2009000609A1 (en) |
| TW (1) | TW200942242A (en) |
| WO (1) | WO2009112231A2 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1598069B1 (en) * | 1999-08-31 | 2009-04-22 | Bayer Schering Pharma Aktiengesellschaft | Pharmaceutical combination of ethinylestradiol and drospirenone for use as a contraceptive |
| US20020132801A1 (en) * | 2001-01-11 | 2002-09-19 | Schering Aktiengesellschaft | Drospirenone for hormone replacement therapy |
| CN1878558A (en) * | 2003-11-14 | 2006-12-13 | 沃纳奇尔科特公司 | Gradient estrogen contraceptives |
| UY29527A1 (en) * | 2005-05-13 | 2006-12-29 | Schering Ag | PHARMACCUTIC COMPOSITION CONTAINING GESTRGENS AND / OR ESTRNGENS AND 5-METHYL - (6S) - TETRHYDROPHOLATE. |
-
2009
- 2009-03-10 WO PCT/EP2009/001687 patent/WO2009112231A2/en not_active Ceased
- 2009-03-10 TW TW098107737A patent/TW200942242A/en unknown
- 2009-03-13 CL CL2009000609A patent/CL2009000609A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW200942242A (en) | 2009-10-16 |
| WO2009112231A2 (en) | 2009-09-17 |
| WO2009112231A3 (en) | 2010-10-21 |
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