CL2009001088A1 - Forma cristalina (ii) de (1r,4r)-4-(1,1-dimetiletilsulfonamido)-n-(5-(trifluorometil) piridin-2-il) ciclohexancarboxamida; procesos de preparacion; utiles como antagonistas del receptor npyy5. - Google Patents

Forma cristalina (ii) de (1r,4r)-4-(1,1-dimetiletilsulfonamido)-n-(5-(trifluorometil) piridin-2-il) ciclohexancarboxamida; procesos de preparacion; utiles como antagonistas del receptor npyy5.

Info

Publication number
CL2009001088A1
CL2009001088A1 CL2009001088A CL2009001088A CL2009001088A1 CL 2009001088 A1 CL2009001088 A1 CL 2009001088A1 CL 2009001088 A CL2009001088 A CL 2009001088A CL 2009001088 A CL2009001088 A CL 2009001088A CL 2009001088 A1 CL2009001088 A1 CL 2009001088A1
Authority
CL
Chile
Prior art keywords
useful
dimethylethylsulfonamido
cyclohexanecarboxamide
pyridin
trifluoromethyl
Prior art date
Application number
CL2009001088A
Other languages
English (en)
Inventor
Sugata Yoshihide
Ide Yutaka
Sakata Teruo
Omura Sohei
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of CL2009001088A1 publication Critical patent/CL2009001088A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedimiento de preparación de compuestos derivados de piridinamida y sus cristales; compuestos intermediarios; útiles como antagonistas del receptor NPYY5.
CL2009001088A 2008-05-08 2009-05-06 Forma cristalina (ii) de (1r,4r)-4-(1,1-dimetiletilsulfonamido)-n-(5-(trifluorometil) piridin-2-il) ciclohexancarboxamida; procesos de preparacion; utiles como antagonistas del receptor npyy5. CL2009001088A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008122154 2008-05-08

Publications (1)

Publication Number Publication Date
CL2009001088A1 true CL2009001088A1 (es) 2011-06-17

Family

ID=41264672

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001088A CL2009001088A1 (es) 2008-05-08 2009-05-06 Forma cristalina (ii) de (1r,4r)-4-(1,1-dimetiletilsulfonamido)-n-(5-(trifluorometil) piridin-2-il) ciclohexancarboxamida; procesos de preparacion; utiles como antagonistas del receptor npyy5.

Country Status (14)

Country Link
US (1) US20110060145A1 (es)
EP (1) EP2275410A4 (es)
JP (2) JP4756565B2 (es)
KR (1) KR101278359B1 (es)
CN (1) CN102015647A (es)
AR (1) AR071695A1 (es)
AU (1) AU2009245113A1 (es)
CA (1) CA2723133A1 (es)
CL (1) CL2009001088A1 (es)
MX (1) MX2010011835A (es)
RU (1) RU2010144412A (es)
TW (1) TWI369350B (es)
WO (1) WO2009136617A1 (es)
ZA (1) ZA201007364B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG174488A1 (en) * 2009-03-19 2011-10-28 Shionogi & Co Solid preparation containing npy y5 receptor antagonist

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2311479T3 (es) * 1999-11-26 2009-02-16 SHIONOGI & CO., LTD. Antagonistas de npy-y5.
CN101104598B (zh) * 2002-03-12 2011-06-15 盐野义制药株式会社 反式-4-氨基-1-环己烷羧酸衍生物的制备方法
JP4636525B2 (ja) * 2004-03-12 2011-02-23 塩野義製薬株式会社 トランス−４−アミノ−１−シクロヘキサンカルボン酸エチルエステルの塩およびその製造方法
BRPI0609529A2 (pt) * 2005-03-31 2010-04-13 Shionogi & Co processo para a preparação de compostos derivados de sulfamato-carboxilato e composto
JP4895230B2 (ja) * 2006-09-28 2012-03-14 塩野義製薬株式会社 ４−スルフィニルアミノ−１−シクロヘキサンカルボン酸の塩の製造方法

Also Published As

Publication number Publication date
ZA201007364B (en) 2012-01-25
JPWO2009136617A1 (ja) 2011-09-08
AR071695A1 (es) 2010-07-07
EP2275410A1 (en) 2011-01-19
CN102015647A (zh) 2011-04-13
JP4756565B2 (ja) 2011-08-24
JP5234856B2 (ja) 2013-07-10
TW200948783A (en) 2009-12-01
KR20110004898A (ko) 2011-01-14
CA2723133A1 (en) 2009-11-12
JP2011178790A (ja) 2011-09-15
TWI369350B (en) 2012-08-01
RU2010144412A (ru) 2012-06-20
WO2009136617A1 (ja) 2009-11-12
KR101278359B1 (ko) 2013-06-25
US20110060145A1 (en) 2011-03-10
EP2275410A4 (en) 2012-05-09
AU2009245113A1 (en) 2009-11-12
MX2010011835A (es) 2010-11-25

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