CL2009001450A1 - Comezcla para compresion directa de comprimidos de rapida desintegracion que comprende 90-98 partes de manitol pulverizado y 10-2 partes de carboximetilcelulosa solida reticulada; formulaciones en comprimidos que comprenden la comezcla; comprimidos y procedimiento para preparar las formulaciones. - Google Patents

Comezcla para compresion directa de comprimidos de rapida desintegracion que comprende 90-98 partes de manitol pulverizado y 10-2 partes de carboximetilcelulosa solida reticulada; formulaciones en comprimidos que comprenden la comezcla; comprimidos y procedimiento para preparar las formulaciones.

Info

Publication number
CL2009001450A1
CL2009001450A1 CL2009001450A CL2009001450A CL2009001450A1 CL 2009001450 A1 CL2009001450 A1 CL 2009001450A1 CL 2009001450 A CL2009001450 A CL 2009001450A CL 2009001450 A CL2009001450 A CL 2009001450A CL 2009001450 A1 CL2009001450 A1 CL 2009001450A1
Authority
CL
Chile
Prior art keywords
parts
tablets
formulations
comix
preparing
Prior art date
Application number
CL2009001450A
Other languages
English (en)
Inventor
Daniela Kleinwaechter
Guenter Moddelmog
Roberto Ognibene
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41134695&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009001450(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of CL2009001450A1 publication Critical patent/CL2009001450A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ES OBJETO DE LA PRESENTE INVENCIÓN UNA NUEVA MATRIZ QUE SE PUEDE COMPRIMIR DIRECTAMENTE PARA PREPARAR COMPRIMIDOS DE RÁPIDA DESINTEGRACION EN PRESENCIA DE HUMEDAD, EN ESPECIAL EN LA BOCA.
CL2009001450A 2008-06-20 2009-06-19 Comezcla para compresion directa de comprimidos de rapida desintegracion que comprende 90-98 partes de manitol pulverizado y 10-2 partes de carboximetilcelulosa solida reticulada; formulaciones en comprimidos que comprenden la comezcla; comprimidos y procedimiento para preparar las formulaciones. CL2009001450A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08011238 2008-06-20
EP08014287 2008-08-11

Publications (1)

Publication Number Publication Date
CL2009001450A1 true CL2009001450A1 (es) 2010-06-11

Family

ID=41134695

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001450A CL2009001450A1 (es) 2008-06-20 2009-06-19 Comezcla para compresion directa de comprimidos de rapida desintegracion que comprende 90-98 partes de manitol pulverizado y 10-2 partes de carboximetilcelulosa solida reticulada; formulaciones en comprimidos que comprenden la comezcla; comprimidos y procedimiento para preparar las formulaciones.

Country Status (15)

Country Link
US (1) US11166917B2 (es)
EP (1) EP2299982B1 (es)
JP (1) JP5756749B2 (es)
KR (1) KR101647855B1 (es)
CN (1) CN102088959B (es)
AR (1) AR072259A1 (es)
BR (1) BRPI0914164B1 (es)
CA (1) CA2728436C (es)
CL (1) CL2009001450A1 (es)
CO (1) CO6321152A2 (es)
ES (1) ES2676288T3 (es)
MX (1) MX2010014209A (es)
RU (1) RU2519768C2 (es)
TR (1) TR201808694T4 (es)
WO (1) WO2009152922A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI556823B (zh) * 2010-04-27 2016-11-11 拜耳智慧財產有限公司 含阿卡波糖之口崩解錠
EP2455069A1 (de) * 2010-11-11 2012-05-23 Laburnum GMBH Wirkstofffreie Darreichungsform, Verfahren zu deren Herstellung sowie deren Verwendung
CN104244931A (zh) * 2012-04-27 2014-12-24 默克专利股份有限公司 经包衣的片剂及其制备
JP6479658B2 (ja) * 2013-07-06 2019-03-06 株式会社ダイセル 超速崩壊錠剤及びその製造方法
AU2023217824A1 (en) * 2022-02-08 2024-08-01 Roquette Freres Directly compressible mannitol granules
FR3132522B1 (fr) * 2022-02-08 2025-04-04 Roquette Freres Granules de mannitol directement comprimable

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US100419A (en) * 1870-03-01 Improved rudder-collar
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JPH08208523A (ja) * 1995-02-03 1996-08-13 Gun Ei Chem Ind Co Ltd 製剤素材
JP2001114712A (ja) * 1996-04-16 2001-04-24 Takeda Chem Ind Ltd Ｄ−マンニトールおよびその製造法
DE19615418A1 (de) * 1996-04-22 1997-10-23 Merck Patent Gmbh Polyol-Zusammensetzung
DE19617487A1 (de) * 1996-05-02 1997-11-06 Merck Patent Gmbh Geschmacksverbesserung von Arzneimittelwirkstoffen
JP3195290B2 (ja) 1997-03-31 2001-08-06 キヤノン株式会社 画像形成装置
US20020071864A1 (en) * 1999-03-25 2002-06-13 Yuhan Corporation Rapidly disintegrable tablet for oral administration
DE19927537A1 (de) * 1999-06-16 2000-12-21 Merck Patent Gmbh Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung
JP3435664B2 (ja) * 1999-12-08 2003-08-11 ヤンセンファーマ株式会社 口腔内速崩壊型錠剤及びその製造方法
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
CA2424770A1 (en) * 2000-10-06 2003-04-03 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation
JPWO2002069934A1 (ja) * 2001-03-06 2004-07-02 協和醗酵工業株式会社 口腔内速崩壊性製剤
DE10161402A1 (de) 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
ES2199061B1 (es) 2002-06-10 2005-02-16 Laboratorios Vita, S.A. Comprimidos bucodispersables y procedimiento para su obtencion.
MXPA05008838A (es) * 2003-02-19 2006-02-17 Biovail Lab Int Srl Formulaciones de absorcion acelerada del agonista selectivo de la 5-ht.
CA2521325C (en) * 2003-04-08 2010-09-14 Novartis Ag Solid pharmaceutical compositions comprising a s1p receptor agonist and a sugar alcohol
US7282217B1 (en) * 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
JP2005306770A (ja) 2004-04-21 2005-11-04 Toa Eiyo Ltd 口腔内速崩壊型製剤及びその製造方法
JP5208348B2 (ja) 2004-05-13 2013-06-12 旭化成ファーマ株式会社 ナフトピジルを含有する医薬
GB0423800D0 (en) * 2004-10-27 2004-12-01 Orexo Ab New pharmaceutical formulations
IS7748A (is) 2005-03-17 2006-09-18 Actavis Group Samsetning fyrir töflur sem innihalda topiramate
JP2008534562A (ja) * 2005-03-28 2008-08-28 オレクソ・アクチエボラゲット 偏頭痛の治療に有用な新しい製薬組成物
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Also Published As

Publication number Publication date
WO2009152922A1 (de) 2009-12-23
EP2299982A1 (de) 2011-03-30
RU2519768C2 (ru) 2014-06-20
US11166917B2 (en) 2021-11-09
RU2011130597A (ru) 2013-01-27
ES2676288T3 (es) 2018-07-18
JP5756749B2 (ja) 2015-07-29
CA2728436A1 (en) 2009-12-23
BRPI0914164B1 (pt) 2019-04-30
TR201808694T4 (tr) 2018-07-23
KR20110022061A (ko) 2011-03-04
CN102088959B (zh) 2016-05-25
EP2299982B1 (de) 2018-04-04
KR101647855B1 (ko) 2016-08-11
CA2728436C (en) 2016-07-26
CO6321152A2 (es) 2011-09-20
AR072259A1 (es) 2010-08-18
MX2010014209A (es) 2011-02-21
US20110091545A1 (en) 2011-04-21
CN102088959A (zh) 2011-06-08
BRPI0914164A2 (pt) 2015-10-20
JP2011524386A (ja) 2011-09-01

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