CL2012001623A1 - Célula de planta que comprende adn que codifica para las proteínas insecticidas cry1da y cry1be, y metodo para controlar un insecto cogollero de otoño, asi como para manejar el desarrollo de resistencia a toxina cry. - Google Patents
Célula de planta que comprende adn que codifica para las proteínas insecticidas cry1da y cry1be, y metodo para controlar un insecto cogollero de otoño, asi como para manejar el desarrollo de resistencia a toxina cry.Info
- Publication number
- CL2012001623A1 CL2012001623A1 CL2012001623A CL2012001623A CL2012001623A1 CL 2012001623 A1 CL2012001623 A1 CL 2012001623A1 CL 2012001623 A CL2012001623 A CL 2012001623A CL 2012001623 A CL2012001623 A CL 2012001623A CL 2012001623 A1 CL2012001623 A1 CL 2012001623A1
- Authority
- CL
- Chile
- Prior art keywords
- cry1be
- cry1da
- managing
- insecticidal proteins
- development
- Prior art date
Links
- 241000256251 Spodoptera frugiperda Species 0.000 title abstract 3
- 230000000749 insecticidal effect Effects 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 239000003053 toxin Substances 0.000 title abstract 2
- 231100000765 toxin Toxicity 0.000 title abstract 2
- 241000238631 Hexapoda Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Pest Control & Pesticides (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Insects & Arthropods (AREA)
- Crystallography & Structural Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Virology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Catching Or Destruction (AREA)
- Cultivation Of Plants (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Peptides Or Proteins (AREA)
- Mycology (AREA)
Abstract
Célula de planta que comprende ADN que codifica para las proteínas insecticidas Cry1Be y Cry1Da; método para manejar el desarrollo de resistencia a una toxina Cry por un insecto, que comprende expresar en una planta las proteínas insecticidas Cry1Be y Cry1Da; y método para controlar gusano cogollero del otoño (Spodoptera Frugiperda).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28429009P | 2009-12-16 | 2009-12-16 | |
| US28425209P | 2009-12-16 | 2009-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012001623A1 true CL2012001623A1 (es) | 2013-01-25 |
Family
ID=44305722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012001623A CL2012001623A1 (es) | 2009-12-16 | 2012-06-15 | Célula de planta que comprende adn que codifica para las proteínas insecticidas cry1da y cry1be, y metodo para controlar un insecto cogollero de otoño, asi como para manejar el desarrollo de resistencia a toxina cry. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9499835B2 (es) |
| EP (1) | EP2513317B1 (es) |
| JP (2) | JP5969921B2 (es) |
| KR (1) | KR101841296B1 (es) |
| CN (1) | CN102753696A (es) |
| AR (1) | AR079506A1 (es) |
| AU (1) | AU2010339919B2 (es) |
| BR (1) | BR112012014727B1 (es) |
| CA (1) | CA2782565A1 (es) |
| CL (1) | CL2012001623A1 (es) |
| CO (1) | CO6561806A2 (es) |
| IL (1) | IL220332A (es) |
| MX (1) | MX350002B (es) |
| NZ (1) | NZ601102A (es) |
| PH (1) | PH12012501434A1 (es) |
| RU (1) | RU2590592C2 (es) |
| WO (1) | WO2011084630A1 (es) |
| ZA (1) | ZA201204925B (es) |
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|---|---|---|---|---|
| BR112012014681B1 (pt) | 2009-12-16 | 2024-03-05 | Dow Agrosciences Llc | Métodos de gerenciamento do desenvolvimento de resistência a plantas transformadas por proteínas cry por uma praga de lepidópteros e de controle de um inseto lagarta-do-cartucho |
| HUE046506T2 (hu) | 2011-06-16 | 2020-03-30 | Univ California | Szintetikus génklaszterek |
| US10119149B2 (en) | 2011-08-05 | 2018-11-06 | Dow Agrosciences Llc | Use of DIG3 insecticidal crystal protein in combination with cry1Ab for management of resistance in european cornborer |
| JP2014525748A (ja) * | 2011-08-05 | 2014-10-02 | ダウ アグロサイエンシィズ エルエルシー | Ｃｒｙ１Ａｂと組み合わせたＤＩＧ３殺虫性結晶タンパク質の使用 |
| EP3395165A1 (en) * | 2012-10-05 | 2018-10-31 | Dow AgroSciences LLC | Use of cry1ea in combinations for management of resistant fall armyworm insects |
| WO2014071182A1 (en) | 2012-11-01 | 2014-05-08 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
| CA2901316A1 (en) | 2013-03-15 | 2014-09-25 | Pioneer Hi-Bred International, Inc. | Phi-4 polypeptides and methods for their use |
| MX359026B (es) | 2013-08-16 | 2018-09-12 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos de uso. |
| CA3223359A1 (en) | 2013-09-13 | 2015-03-19 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CA3290904A1 (en) | 2014-02-07 | 2026-03-02 | E. I. Du Pont De Nemours And Company | Insecticidal proteins and methods for their use |
| WO2015120270A1 (en) | 2014-02-07 | 2015-08-13 | Pioneer Hi Bred International, Inc. | Insecticidal proteins and methods for their use |
| TW201542093A (zh) * | 2014-03-21 | 2015-11-16 | 艾格里遺傳學股份有限公司 | 用於控制玉米穗蟲之Ｃｒｙ１Ｄ |
| WO2016000237A1 (en) | 2014-07-03 | 2016-01-07 | Pioneer Overseas Corporation | Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes |
| CA2963558C (en) | 2014-10-16 | 2023-04-04 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CN107635396B (zh) | 2015-01-15 | 2021-12-24 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| CN107529763B (zh) | 2015-03-11 | 2021-08-20 | 先锋国际良种公司 | Pip-72的杀昆虫组合及使用方法 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN116333064A (zh) | 2015-05-19 | 2023-06-27 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| AU2016278142A1 (en) | 2015-06-16 | 2017-11-30 | E. I. Du Pont De Nemours And Company | Compositions and methods to control insect pests |
| CN108602729B (zh) | 2015-07-13 | 2022-07-05 | 皮沃特生物公司 | 改良植物性状的方法及组合物 |
| CA3268091A1 (en) | 2015-08-06 | 2026-03-02 | Pioneer Hi-Bred International, Inc. | Plant derived insecticidal proteins and methods for their use |
| CN108513584A (zh) | 2015-08-28 | 2018-09-07 | 先锋国际良种公司 | 苍白杆菌介导的植物转化 |
| WO2017062412A1 (en) | 2015-10-05 | 2017-04-13 | Massachusetts Institute Of Technology | Nitrogen fixation using refactored nif clusters |
| WO2017105987A1 (en) | 2015-12-18 | 2017-06-22 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| CN108699117B (zh) | 2016-04-14 | 2023-06-23 | 先锋国际良种公司 | 具有改善的活性谱的杀昆虫多肽及其用途 |
| CA3021391A1 (en) | 2016-04-19 | 2017-10-26 | Pioneer Hi-Bred International, Inc. | Insecticidal combinations of polypeptides having improved activity spectrum and uses thereof |
| MX387077B (es) | 2016-05-04 | 2025-03-19 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para sus usos. |
| WO2017218207A1 (en) | 2016-06-16 | 2017-12-21 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| ES2924552T3 (es) | 2016-06-24 | 2022-10-07 | Pioneer Hi Bred Int | Elementos reguladores de las plantas y métodos de uso de los mismos |
| CA3026113A1 (en) | 2016-07-01 | 2018-01-04 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins from plants and methods for their use |
| WO2018013333A1 (en) | 2016-07-12 | 2018-01-18 | Pioneer Hi-Bred International, Inc. | Compositions and methods to control insect pests |
| US10626151B2 (en) | 2016-10-10 | 2020-04-21 | Monsanto Technology Llc | Insect inhibitory proteins |
| MX387927B (es) | 2016-11-01 | 2025-03-19 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para su uso. |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3555118B1 (en) | 2016-12-14 | 2021-08-18 | Pioneer Hi-Bred International Inc. | Insecticidal proteins and methods for their use |
| WO2018118811A1 (en) | 2016-12-22 | 2018-06-28 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| JP7234116B2 (ja) | 2017-01-12 | 2023-03-07 | ピボット バイオ， インコーポレイテッド | 植物形質を改善するための方法および組成物 |
| WO2018140214A1 (en) | 2017-01-24 | 2018-08-02 | Pioneer Hi-Bred International, Inc. | Nematicidal protein from pseudomonas |
| MX2019009371A (es) | 2017-02-08 | 2019-09-23 | Pionner Hi Bred Int Inc | Combinaciones insecticidas de proteinas insecticidas derivadas de plantas y metodos para su uso. |
| MX2019013321A (es) | 2017-05-11 | 2020-02-10 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para su uso. |
| CA3064884A1 (en) | 2017-05-26 | 2018-11-29 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides having improved activity spectrum and uses thereof |
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| AU2018354221B2 (en) | 2017-10-25 | 2025-04-17 | Pivot Bio, Inc. | Methods and compositions for improving engineered microbes that fix nitrogen |
| WO2019165245A1 (en) | 2018-02-22 | 2019-08-29 | Zymergen Inc. | Method for creating a genomic library enriched for bacillus and identification of novel cry toxins |
| CA3087861A1 (en) | 2018-03-02 | 2019-09-06 | Pioneer Hi-Bred International, Inc. | Plant health assay |
| WO2019169227A1 (en) | 2018-03-02 | 2019-09-06 | Zymergen Inc. | Insecticidal protein discovery platform and insecticidal proteins discovered therefrom |
| CN111867377B (zh) | 2018-03-14 | 2023-05-23 | 先锋国际良种公司 | 来自植物的杀昆虫蛋白及其使用方法 |
| AU2019234566B2 (en) | 2018-03-14 | 2024-09-26 | Hexima Limited | Insecticidal proteins from plants and methods for their use |
| US11702668B2 (en) | 2018-05-22 | 2023-07-18 | Pioneer Hi-Bred International, Inc. | Plant regulatory elements and methods of use thereof |
| CN112739668A (zh) | 2018-06-27 | 2021-04-30 | 皮沃特生物股份有限公司 | 包括重构固氮微生物的农业组合物 |
| KR20210060434A (ko) | 2018-07-11 | 2021-05-26 | 피벗 바이오, 인크. | 리모델링된 미생물에 의한 시간적 및 공간적 표적화 동적 질소 전달 |
| AU2019314261B2 (en) * | 2018-07-30 | 2023-03-30 | Monsanto Technology Llc | Corn transgenic event MON 95379 and methods for detection and uses thereof |
| US11878999B2 (en) | 2018-08-29 | 2024-01-23 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| WO2020190363A1 (en) | 2019-03-19 | 2020-09-24 | Massachusetts Institute Of Technology | Control of nitrogen fixation in rhizobia that associate with cereals |
| CN110317242B (zh) * | 2019-06-12 | 2021-03-26 | 南昌大学 | 可特异性结合Cry1Da蛋白的多肽分子及其应用 |
| WO2021076346A1 (en) | 2019-10-18 | 2021-04-22 | Pioneer Hi-Bred International, Inc. | Maize event dp-202216-6 and dp-023211-2 stack |
| WO2021221690A1 (en) | 2020-05-01 | 2021-11-04 | Pivot Bio, Inc. | Modified bacterial strains for improved fixation of nitrogen |
| AU2020445067A1 (en) | 2020-05-01 | 2022-12-01 | Pivot Bio, Inc. | Measurement of nitrogen fixation and incorporation |
| EP4143211A2 (en) | 2020-05-01 | 2023-03-08 | Pivot Bio, Inc. | Modified bacterial strains for improved fixation of nitrogen |
| US12168774B2 (en) | 2020-07-14 | 2024-12-17 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
| BR112023002603A2 (pt) | 2020-08-10 | 2023-04-04 | Pioneer Hi Bred Int | Elementos reguladores de plantas e métodos de uso dos mesmos |
| CA3218556A1 (en) | 2021-07-02 | 2023-01-05 | Pivot Bio, Inc. | Genetically-engineered bacterial strains for improved fixation of nitrogen |
| US20250171792A1 (en) * | 2022-02-23 | 2025-05-29 | Pioneer Hi-Bred International, Inc. | Multiple disease resistance genes and genomic stacks thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0400246A1 (en) * | 1989-05-31 | 1990-12-05 | Plant Genetic Systems, N.V. | Prevention of Bt resistance development |
| US5188960A (en) * | 1989-06-27 | 1993-02-23 | Mycogen Corporation | Bacillus thuringiensis isolate active against lepidopteran pests, and genes encoding novel lepidopteran-active toxins |
| US5723758A (en) * | 1991-09-13 | 1998-03-03 | Mycogen Corporation | Bacillus thuringiensis genes encoding lepidopteran-active toxins |
| GB9318207D0 (en) * | 1993-09-02 | 1993-10-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5942664A (en) * | 1996-11-27 | 1999-08-24 | Ecogen, Inc. | Bacillus thuringiensis Cry1C compositions toxic to lepidopteran insects and methods for making Cry1C mutants |
| US6218188B1 (en) * | 1997-11-12 | 2001-04-17 | Mycogen Corporation | Plant-optimized genes encoding pesticidal toxins |
| AU7491600A (en) * | 1999-09-15 | 2001-04-17 | Monsanto Technology Llc | Lepidopteran-active bacillus thuringiensis delta-endotoxin compositions and methods of use |
| AR048747A1 (es) * | 2004-03-05 | 2006-05-24 | Agrigenetics Inc | Combinaciones de cry1ab y cry1fa como una herramienta para el control de la resistencia de los insectos |
| BRPI0911589A2 (pt) * | 2008-05-01 | 2015-08-04 | Bayer Bioscience Nv | Manejo de resistência do inseto lagarta do cartucho em plantas transgênicas |
| KR20140014371A (ko) * | 2009-04-17 | 2014-02-06 | 다우 아그로사이언시즈 엘엘씨 | 살충성 ｄｉｇ-3 ｃｒｙ 독소 |
-
2010
- 2010-12-16 EP EP10842619.8A patent/EP2513317B1/en active Active
- 2010-12-16 JP JP2012544845A patent/JP5969921B2/ja not_active Expired - Fee Related
- 2010-12-16 RU RU2012129910/10A patent/RU2590592C2/ru not_active IP Right Cessation
- 2010-12-16 KR KR1020127018336A patent/KR101841296B1/ko not_active Expired - Fee Related
- 2010-12-16 WO PCT/US2010/060829 patent/WO2011084630A1/en not_active Ceased
- 2010-12-16 NZ NZ601102A patent/NZ601102A/en not_active IP Right Cessation
- 2010-12-16 US US13/516,665 patent/US9499835B2/en active Active
- 2010-12-16 MX MX2012007126A patent/MX350002B/es active IP Right Grant
- 2010-12-16 BR BR112012014727A patent/BR112012014727B1/pt not_active IP Right Cessation
- 2010-12-16 PH PH1/2012/501434A patent/PH12012501434A1/en unknown
- 2010-12-16 AU AU2010339919A patent/AU2010339919B2/en not_active Ceased
- 2010-12-16 AR ARP100104679 patent/AR079506A1/es unknown
- 2010-12-16 CN CN2010800639087A patent/CN102753696A/zh active Pending
- 2010-12-16 CA CA2782565A patent/CA2782565A1/en not_active Abandoned
-
2012
- 2012-06-12 IL IL220332A patent/IL220332A/en not_active IP Right Cessation
- 2012-06-15 CL CL2012001623A patent/CL2012001623A1/es unknown
- 2012-07-02 ZA ZA2012/04925A patent/ZA201204925B/en unknown
- 2012-07-16 CO CO12119364A patent/CO6561806A2/es not_active Application Discontinuation
-
2016
- 2016-02-08 JP JP2016021704A patent/JP2016154536A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN102753696A (zh) | 2012-10-24 |
| WO2011084630A1 (en) | 2011-07-14 |
| EP2513317A4 (en) | 2013-10-02 |
| JP2016154536A (ja) | 2016-09-01 |
| NZ601102A (en) | 2014-10-31 |
| US20120331590A1 (en) | 2012-12-27 |
| EP2513317A1 (en) | 2012-10-24 |
| IL220332A (en) | 2017-12-31 |
| EP2513317B1 (en) | 2018-01-24 |
| KR101841296B1 (ko) | 2018-03-22 |
| CA2782565A1 (en) | 2011-07-14 |
| JP2013514774A (ja) | 2013-05-02 |
| JP5969921B2 (ja) | 2016-08-17 |
| BR112012014727B1 (pt) | 2019-09-03 |
| RU2590592C2 (ru) | 2016-07-10 |
| AU2010339919A1 (en) | 2012-07-12 |
| AR079506A1 (es) | 2012-02-01 |
| KR20120115980A (ko) | 2012-10-19 |
| AU2010339919B2 (en) | 2016-01-21 |
| US9499835B2 (en) | 2016-11-22 |
| IL220332A0 (en) | 2012-08-30 |
| MX350002B (es) | 2017-08-22 |
| RU2012129910A (ru) | 2014-01-27 |
| MX2012007126A (es) | 2012-11-12 |
| ZA201204925B (en) | 2013-03-27 |
| PH12012501434A1 (en) | 2012-10-22 |
| BR112012014727A2 (pt) | 2015-08-25 |
| CO6561806A2 (es) | 2012-11-15 |
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