CL2013000927A1 - Compuestos derivados de de 1,4-oxazepina, inhibidores de la recaptacion de monoaminas; un medicamento; y su uso preventivo o terapeutico para depresion, ansiedad, tdah, ansiedad, entre otros. - Google Patents
Compuestos derivados de de 1,4-oxazepina, inhibidores de la recaptacion de monoaminas; un medicamento; y su uso preventivo o terapeutico para depresion, ansiedad, tdah, ansiedad, entre otros.Info
- Publication number
- CL2013000927A1 CL2013000927A1 CL2013000927A CL2013000927A CL2013000927A1 CL 2013000927 A1 CL2013000927 A1 CL 2013000927A1 CL 2013000927 A CL2013000927 A CL 2013000927A CL 2013000927 A CL2013000927 A CL 2013000927A CL 2013000927 A1 CL2013000927 A1 CL 2013000927A1
- Authority
- CL
- Chile
- Prior art keywords
- anxiety
- oxazepine
- adhd
- preventive
- medication
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010227864 | 2010-10-07 | ||
| JP2011175336 | 2011-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013000927A1 true CL2013000927A1 (es) | 2013-09-13 |
Family
ID=44906302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013000927A CL2013000927A1 (es) | 2010-10-07 | 2013-04-05 | Compuestos derivados de de 1,4-oxazepina, inhibidores de la recaptacion de monoaminas; un medicamento; y su uso preventivo o terapeutico para depresion, ansiedad, tdah, ansiedad, entre otros. |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US8722662B2 (es) |
| EP (1) | EP2625170A1 (es) |
| JP (1) | JP5873487B2 (es) |
| KR (1) | KR20130116073A (es) |
| CN (1) | CN103261176B (es) |
| AR (1) | AR083313A1 (es) |
| AU (1) | AU2011313150A1 (es) |
| BR (1) | BR112013008420A2 (es) |
| CA (1) | CA2813911A1 (es) |
| CL (1) | CL2013000927A1 (es) |
| CO (1) | CO6700872A2 (es) |
| CR (1) | CR20130158A (es) |
| DO (1) | DOP2013000074A (es) |
| EA (1) | EA201390491A1 (es) |
| EC (1) | ECSP13012593A (es) |
| GE (1) | GEP20156295B (es) |
| IL (1) | IL225189A0 (es) |
| MX (1) | MX2013003749A (es) |
| NZ (1) | NZ608499A (es) |
| PE (1) | PE20140239A1 (es) |
| PH (1) | PH12013500657A1 (es) |
| SG (1) | SG188346A1 (es) |
| TW (1) | TW201242956A (es) |
| UY (1) | UY33650A (es) |
| WO (1) | WO2012046882A1 (es) |
| ZA (1) | ZA201302112B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013093484A1 (en) * | 2011-12-21 | 2013-06-27 | Ono Pharmaceutical Co., Ltd. | Pyridinone and pyrimidinone derivatives as factor xia inhibitors |
| US9475809B2 (en) * | 2013-07-23 | 2016-10-25 | Bayer Pharma Aktiengesellschaft | Substituted oxopyridine derivatives and use thereof as factor xia/plasma |
| CN105693652B (zh) * | 2014-11-27 | 2019-01-08 | 常州合全药业有限公司 | 一种4-叔丁基-5-乙基-6-氧亚基-1,4-噁吖庚环-4,5-二甲酸基酯的合成方法 |
| WO2016093285A1 (ja) | 2014-12-10 | 2016-06-16 | 小野薬品工業株式会社 | ジヒドロインドリジノン誘導体 |
| JP2018516887A (ja) | 2015-05-08 | 2018-06-28 | ヴァーテラス ホールディングス エルエルシー | カルボキサミドをチオカルボキサミドに変換するための方法 |
| WO2024251807A1 (en) * | 2023-06-08 | 2024-12-12 | Cybin Irl Limited | Companion animal treatments |
| JP2026525234A (ja) * | 2023-06-27 | 2026-07-29 | ライカルマ・セラピューティクス，インコーポレーテッド | リアノジン受容体が関与する障害を処置するための作用剤 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3018222A (en) | 1956-08-28 | 1962-01-23 | Ravensberg G M B H | Central stimulant and appetite depressant composition |
| US4010166A (en) | 1974-11-25 | 1977-03-01 | Ciba-Geigy Corporation | 1,4-Oxazepines |
| DE3242923A1 (de) | 1982-11-20 | 1984-05-24 | Basf Ag, 6700 Ludwigshafen | 7-phenyl-7-phenoxymethyl-hexahydro-1,4-oxazepine, ihre herstellung und verwendung |
| CA2214247C (en) | 1995-03-14 | 2004-02-10 | Praecis Pharmaceuticals Incorporated | Modulators of amyloid aggregation |
| JP2992677B2 (ja) | 1995-06-05 | 1999-12-20 | 武田薬品工業株式会社 | 骨形成促進医薬組成物 |
| ZA971525B (en) | 1996-02-22 | 1997-10-21 | Neurosearch As | Tropane derivatives, their preparation and use. |
| EP1586584A1 (en) | 1996-08-27 | 2005-10-19 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation comprising D-amino acids |
| EP1324993A2 (en) | 2000-04-18 | 2003-07-09 | Cytovia, Inc. | Substituted 1,4-thiazepine and analogs as activators of caspases and inducers of apoptosis and the use thereof |
| TW200502221A (en) * | 2002-10-03 | 2005-01-16 | Astrazeneca Ab | Novel lactams and uses thereof |
| GB0229743D0 (en) * | 2002-12-20 | 2003-01-29 | Arakis Ltd | Novel benzoxazocines |
| GB0303852D0 (en) | 2003-02-19 | 2003-03-26 | Pfizer Ltd | Triazole compounds useful in therapy |
| BRPI0618011A2 (pt) | 2005-10-28 | 2011-08-16 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação do mesmo, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, e, métodos para produzir um efeito anti-proliferativo e um efeito pró-apoptósico em um animal de sangue quente, para tratar doença e para produzir um efeito inibidor de jak em um animal de sangue quente |
| US20090054398A1 (en) | 2006-03-10 | 2009-02-26 | Astrazeneca Ab | Chemical compounds |
| AU2007267182A1 (en) | 2006-05-31 | 2007-12-06 | F. Hoffmann-La Roche Ag | Benzazepine derivatives as monoamine reuptake inhibitors |
| EA200970510A1 (ru) | 2006-11-24 | 2009-12-30 | Такеда Фармасьютикал Компани Лимитед | Гетеромоноциклическое соединение и его применение |
| GB0721178D0 (en) | 2007-10-29 | 2007-12-05 | Glaxo Group Ltd | Chemical compounds |
| WO2009119528A1 (ja) | 2008-03-24 | 2009-10-01 | 武田薬品工業株式会社 | 複素環化合物 |
| WO2010016554A1 (ja) | 2008-08-07 | 2010-02-11 | 武田薬品工業株式会社 | 環状アミン化合物 |
-
2011
- 2011-10-05 EP EP11778987.5A patent/EP2625170A1/en not_active Withdrawn
- 2011-10-05 NZ NZ60849911A patent/NZ608499A/en not_active IP Right Cessation
- 2011-10-05 TW TW100136019A patent/TW201242956A/zh unknown
- 2011-10-05 BR BR112013008420A patent/BR112013008420A2/pt not_active IP Right Cessation
- 2011-10-05 UY UY0001033650A patent/UY33650A/es unknown
- 2011-10-05 GE GEAP201113078A patent/GEP20156295B/en unknown
- 2011-10-05 AR ARP110103695A patent/AR083313A1/es unknown
- 2011-10-05 JP JP2013515601A patent/JP5873487B2/ja not_active Expired - Fee Related
- 2011-10-05 US US13/253,293 patent/US8722662B2/en not_active Expired - Fee Related
- 2011-10-05 AU AU2011313150A patent/AU2011313150A1/en not_active Abandoned
- 2011-10-05 CN CN201180059036.1A patent/CN103261176B/zh not_active Expired - Fee Related
- 2011-10-05 EA EA201390491A patent/EA201390491A1/ru unknown
- 2011-10-05 SG SG2013015268A patent/SG188346A1/en unknown
- 2011-10-05 CA CA2813911A patent/CA2813911A1/en not_active Abandoned
- 2011-10-05 PH PH1/2013/500657A patent/PH12013500657A1/en unknown
- 2011-10-05 US US13/877,810 patent/US20130267494A1/en not_active Abandoned
- 2011-10-05 WO PCT/JP2011/073745 patent/WO2012046882A1/en not_active Ceased
- 2011-10-05 KR KR1020137011425A patent/KR20130116073A/ko not_active Withdrawn
- 2011-10-05 PE PE2013000801A patent/PE20140239A1/es not_active Application Discontinuation
- 2011-10-05 MX MX2013003749A patent/MX2013003749A/es active IP Right Grant
-
2013
- 2013-03-13 IL IL225189A patent/IL225189A0/en unknown
- 2013-03-20 ZA ZA2013/02112A patent/ZA201302112B/en unknown
- 2013-04-04 CR CR20130158A patent/CR20130158A/es not_active Application Discontinuation
- 2013-04-04 DO DO2013000074A patent/DOP2013000074A/es unknown
- 2013-04-05 CL CL2013000927A patent/CL2013000927A1/es unknown
- 2013-04-29 EC ECSP13012593 patent/ECSP13012593A/es unknown
- 2013-05-07 CO CO13114306A patent/CO6700872A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013538786A (ja) | 2013-10-17 |
| UY33650A (es) | 2012-04-30 |
| ZA201302112B (en) | 2013-12-23 |
| WO2012046882A1 (en) | 2012-04-12 |
| JP5873487B2 (ja) | 2016-03-01 |
| EA201390491A1 (ru) | 2013-11-29 |
| US20130267494A1 (en) | 2013-10-10 |
| US20120088748A1 (en) | 2012-04-12 |
| AU2011313150A1 (en) | 2013-04-18 |
| PH12013500657A1 (en) | 2013-05-06 |
| MX2013003749A (es) | 2013-05-09 |
| EP2625170A1 (en) | 2013-08-14 |
| ECSP13012593A (es) | 2013-07-31 |
| NZ608499A (en) | 2015-03-27 |
| DOP2013000074A (es) | 2014-07-31 |
| PE20140239A1 (es) | 2014-03-07 |
| US8722662B2 (en) | 2014-05-13 |
| CN103261176B (zh) | 2015-06-03 |
| CN103261176A (zh) | 2013-08-21 |
| GEP20156295B (en) | 2015-06-10 |
| BR112013008420A2 (pt) | 2016-06-28 |
| CO6700872A2 (es) | 2013-06-28 |
| AR083313A1 (es) | 2013-02-13 |
| KR20130116073A (ko) | 2013-10-22 |
| IL225189A0 (en) | 2013-06-27 |
| TW201242956A (en) | 2012-11-01 |
| SG188346A1 (en) | 2013-04-30 |
| CA2813911A1 (en) | 2012-04-12 |
| CR20130158A (es) | 2013-05-03 |
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