CL2013002138A1 - Metodo para modificar geneticamente una planta para incrementar la produccion de un producto biosintetico en un tejido deseado; y metodo para modificar geneticamente una planta que tiene deposicion de lignina que es sustancialmente localizada en los vasos de tejido de xilema de la planta - Google Patents
Metodo para modificar geneticamente una planta para incrementar la produccion de un producto biosintetico en un tejido deseado; y metodo para modificar geneticamente una planta que tiene deposicion de lignina que es sustancialmente localizada en los vasos de tejido de xilema de la plantaInfo
- Publication number
- CL2013002138A1 CL2013002138A1 CL2013002138A CL2013002138A CL2013002138A1 CL 2013002138 A1 CL2013002138 A1 CL 2013002138A1 CL 2013002138 A CL2013002138 A CL 2013002138A CL 2013002138 A CL2013002138 A CL 2013002138A CL 2013002138 A1 CL2013002138 A1 CL 2013002138A1
- Authority
- CL
- Chile
- Prior art keywords
- plant
- genetically
- tissue
- production
- increase
- Prior art date
Links
- 230000001851 biosynthetic effect Effects 0.000 title 1
- 230000008021 deposition Effects 0.000 title 1
- 229920005610 lignin Polymers 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8247—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8217—Gene switch
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8222—Developmentally regulated expression systems, tissue, organ specific, temporal or spatial regulation
- C12N15/8223—Vegetative tissue-specific promoters
- C12N15/8226—Stem-specific, e.g. including tubers, beets
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
- C12N15/8246—Non-starch polysaccharides, e.g. cellulose, fructans, levans
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8255—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving lignin biosynthesis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Nutrition Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161437569P | 2011-01-28 | 2011-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2013002138A1 true CL2013002138A1 (es) | 2014-03-07 |
Family
ID=46581454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2013002138A CL2013002138A1 (es) | 2011-01-28 | 2013-07-26 | Metodo para modificar geneticamente una planta para incrementar la produccion de un producto biosintetico en un tejido deseado; y metodo para modificar geneticamente una planta que tiene deposicion de lignina que es sustancialmente localizada en los vasos de tejido de xilema de la planta |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20140298539A1 (es) |
| CN (2) | CN107674882B (es) |
| BR (1) | BR112013018836A2 (es) |
| CL (1) | CL2013002138A1 (es) |
| MX (2) | MX2013008710A (es) |
| WO (1) | WO2012103555A2 (es) |
Families Citing this family (44)
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| US9650643B2 (en) | 2012-02-27 | 2017-05-16 | Board Of Trustees Of Michigan State University | Control of cellulose biosynthesis by overexpression of a transcription factor |
| WO2013170201A2 (en) | 2012-05-10 | 2013-11-14 | The Regents Of The University Of California | Regulation of galactan synthase expression to modify galactan content in plants |
| WO2014018982A1 (en) | 2012-07-27 | 2014-01-30 | The Regents Of The University Of California | Systems and methods for enhancing gene expression |
| EP2880165A4 (en) * | 2012-08-03 | 2016-03-16 | Adelaide Res &Innovation Pty Ltd | POLYSACCHARIDE SYNTHASES (X) |
| GB201223097D0 (en) | 2012-12-20 | 2013-02-06 | Max Planck Gesellschaft | Stable transformation of a population and a method of biocontainment using haploinsufficiency and underdominance principles |
| WO2014100742A2 (en) | 2012-12-21 | 2014-06-26 | The Regents Of The University Of California | Modulation of expression of acyltransferases to modify hydroxycinnamic acid content |
| US10227573B2 (en) | 2013-03-15 | 2019-03-12 | The Regents Of The University Of California | Dominant negative mutations of Arabidopsis RWA |
| CN103409441A (zh) * | 2013-07-29 | 2013-11-27 | 中国农业大学 | 柳枝稷木质素合成酶f5h2基因序列 |
| CN105658798A (zh) * | 2013-10-21 | 2016-06-08 | 瑞典树木科技公司 | 具有降低的木聚糖含量的转基因树 |
| US9944939B2 (en) | 2013-11-13 | 2018-04-17 | Board Of Trustees Of Michigan State University | CslA9 gluco-mannan synthase gene |
| CN103695406A (zh) * | 2013-12-16 | 2014-04-02 | 上海交通大学 | 郁金香苯丙氨酸解氨酶TfPAL蛋白及其编码基因 |
| US10774338B2 (en) | 2014-01-16 | 2020-09-15 | The Regents Of The University Of California | Generation of heritable chimeric plant traits |
| CN104561044B (zh) * | 2015-01-16 | 2017-07-25 | 东北林业大学 | 一种提高白桦抗逆性的基因及其编码的蛋白 |
| KR101797713B1 (ko) * | 2015-05-14 | 2017-11-16 | 한국과학기술원 | 신남알데하이드의 제조 방법 |
| US10253324B2 (en) | 2015-09-30 | 2019-04-09 | The United States Of America, As Represented By The Secretary Of Agriculture | Genetically altered alfalfa producing clovamide and/or related hydroxycinnamoyl amides |
| CN105925591B (zh) * | 2016-04-22 | 2019-12-24 | 浙江农林大学 | 一种毛竹木聚糖合成关键基因PeIRX10的克隆及其应用 |
| WO2017216704A1 (en) * | 2016-06-13 | 2017-12-21 | Benson Hill Biosystems, Inc. | Increasing plant growth and yield by using a phenylalanine ammonia lyase sequence |
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| WO2019053073A1 (en) * | 2017-09-13 | 2019-03-21 | Vib Vzw | MEANS AND METHODS FOR INCREASING BIOMASS VEGETAL |
| JP7039005B2 (ja) * | 2017-12-28 | 2022-03-22 | 国立大学法人東海国立大学機構 | 植物由来のアルカン合成酵素遺伝子を導入した細胞を用いるアルカンの製造方法 |
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| CN108531504A (zh) * | 2018-04-04 | 2018-09-14 | 辽宁大学 | 一种利用基因工程手段高效创制低木质素含量紫花苜蓿的方法 |
| BR112020026795A2 (pt) * | 2018-06-29 | 2021-03-30 | Board Of Trustees Of Michigan State University | Forma constitutivamente ativa de myb46 |
| CN109576284B (zh) * | 2018-12-21 | 2021-09-17 | 中国农业科学院北京畜牧兽医研究所 | 一个多功能的myb转录因子基因及其用途 |
| US12037592B2 (en) | 2019-02-20 | 2024-07-16 | The Regents Of The University Of California | Plants and methods for producing muconic acid |
| CN110066813B (zh) * | 2019-03-31 | 2021-01-26 | 浙江大学 | 一种调控杨树木材形成的油菜素内酯合成限速基因及其应用 |
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| CN111410684A (zh) * | 2020-05-12 | 2020-07-14 | 中国农业科学院作物科学研究所 | SiMYB30蛋白质及其相关生物材料在调控植物耐逆性和产量中的应用 |
| CN111499713B (zh) * | 2020-06-10 | 2022-03-18 | 华中农业大学 | 水稻粒型基因qGL6-2及其应用 |
| US12600977B2 (en) | 2020-10-14 | 2026-04-14 | The Regents Of The University Of California | Plants and methods for producing 2-pyrone-4, 6-dicarboxylic acid (PDC) |
| CN113234734B (zh) * | 2021-03-22 | 2022-10-25 | 成都大学 | 一种可提高植物抗性的甜橙基因CsMYB30及其应用 |
| CN113403322B (zh) * | 2021-05-14 | 2022-09-16 | 云南大学 | 一种茶树干旱响应基因CsNAC168及其编码蛋白和应用 |
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| CN116987710B (zh) * | 2023-08-07 | 2024-05-28 | 西部(重庆)科学城种质创制大科学中心 | 马铃薯耐旱性相关基因StMYB55及其应用 |
| CN117603989B (zh) * | 2023-11-08 | 2026-04-21 | 国际竹藤中心 | 金镶玉竹环状RNA PacircPEX及其应用 |
| WO2025105477A1 (ja) * | 2023-11-17 | 2025-05-22 | 国立研究開発法人産業技術総合研究所 | 転写因子遺伝子の塩基置換によって二次細胞壁を増強させた植物の作製方法 |
| CN117701585B (zh) * | 2023-11-18 | 2025-12-12 | 南京农业大学 | 紫花苜蓿MYB转录因子MsMYB306基因及其应用 |
| CN117535310B (zh) * | 2023-12-05 | 2026-04-03 | 西北农林科技大学 | 一种紫花苜蓿抑制木质素合成相关基因及其应用 |
| CN118064491B (zh) * | 2023-12-07 | 2025-06-24 | 四川农业大学 | 水稻基因OsGUX1及其应用 |
| CN118531059B (zh) * | 2024-07-26 | 2024-10-11 | 吉林农业大学 | GmMYB85基因在调控植物油脂合成中的应用 |
| CN120041468B (zh) * | 2025-02-21 | 2025-11-14 | 湖北省农业科学院粮食作物研究所 | 一种OsMYB58基因在提高褐飞虱抗性中的应用 |
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|---|---|---|---|---|
| US6410718B1 (en) * | 1996-09-11 | 2002-06-25 | Genesis Research & Development Corporation Ltd. | Materials and methods for the modification of plant lignin content |
| US10329575B2 (en) * | 1999-05-14 | 2019-06-25 | Ceres, Inc. | Regulatory sequence for plants |
| US7547534B2 (en) * | 2002-06-14 | 2009-06-16 | Verenium Corporation | Methods for making a composition to treat a wood, a pulp or a paper |
| US7238512B2 (en) * | 2003-10-17 | 2007-07-03 | E. I. Du Pont De Nemours And Company | Method to produce para-hydroxybenzoic acid in the stem tissue of green plants by using a tissue-specific promoter |
| AU2005295420B2 (en) * | 2004-10-18 | 2011-04-14 | The Samuel Roberts Noble Foundation, Inc. | Increased wax production in plants |
| WO2007102346A1 (ja) * | 2006-02-28 | 2007-09-13 | Japan Science And Technology Agency | グルカン量を低減させることなくリグニン量およびセルロース量を低減させた植物体およびその生産方法、並びにこれらの利用 |
| GB0718377D0 (en) * | 2007-09-21 | 2007-10-31 | Cambridge Entpr Ltd | Improvements in or relating to organic compounds |
| WO2009045627A2 (en) * | 2007-10-03 | 2009-04-09 | Verenium Corporation | Xylanases, nucleic acids encoding them and methods for making and using them |
| US8796509B2 (en) * | 2009-07-13 | 2014-08-05 | The Samuel Roberts Noble Foundation | Plants with modified lignin content and methods for production thereof |
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2012
- 2012-01-30 CN CN201710806695.6A patent/CN107674882B/zh active Active
- 2012-01-30 CN CN201280010285.6A patent/CN103403016B/zh active Active
- 2012-01-30 MX MX2013008710A patent/MX2013008710A/es unknown
- 2012-01-30 BR BR112013018836A patent/BR112013018836A2/pt not_active Application Discontinuation
- 2012-01-30 WO PCT/US2012/023182 patent/WO2012103555A2/en not_active Ceased
- 2012-01-30 US US13/982,231 patent/US20140298539A1/en not_active Abandoned
-
2013
- 2013-07-26 CL CL2013002138A patent/CL2013002138A1/es unknown
- 2013-07-26 MX MX2018013482A patent/MX2018013482A/es unknown
-
2018
- 2018-09-06 US US16/123,739 patent/US20190062771A1/en not_active Abandoned
-
2022
- 2022-04-06 US US17/714,931 patent/US20220380790A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012103555A2 (en) | 2012-08-02 |
| CN107674882B (zh) | 2021-06-25 |
| WO2012103555A3 (en) | 2012-10-04 |
| MX2018013482A (es) | 2019-12-09 |
| MX2013008710A (es) | 2013-08-21 |
| US20220380790A1 (en) | 2022-12-01 |
| US20190062771A1 (en) | 2019-02-28 |
| CN103403016A (zh) | 2013-11-20 |
| US20140298539A1 (en) | 2014-10-02 |
| BR112013018836A2 (pt) | 2016-07-19 |
| CN107674882A (zh) | 2018-02-09 |
| CN103403016B (zh) | 2017-10-24 |
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