CL2014000863A1 - Una composicion oftalmologica que comprende monooleato de polioxietileno (80) sorbitan, carboximetilcelulosa sodica, glicerina, acido borico, polimero reticulado de acrilatos/acrilato de alquilo c10-30, aceite de ricino, eritritol, levocarnitina, hidroxido de sodio y agua; y su uso para tratar, mitigar o prevenir el sindrome del ojo seco. - Google Patents

Una composicion oftalmologica que comprende monooleato de polioxietileno (80) sorbitan, carboximetilcelulosa sodica, glicerina, acido borico, polimero reticulado de acrilatos/acrilato de alquilo c10-30, aceite de ricino, eritritol, levocarnitina, hidroxido de sodio y agua; y su uso para tratar, mitigar o prevenir el sindrome del ojo seco.

Info

Publication number
CL2014000863A1
CL2014000863A1 CL2014000863A CL2014000863A CL2014000863A1 CL 2014000863 A1 CL2014000863 A1 CL 2014000863A1 CL 2014000863 A CL2014000863 A CL 2014000863A CL 2014000863 A CL2014000863 A CL 2014000863A CL 2014000863 A1 CL2014000863 A1 CL 2014000863A1
Authority
CL
Chile
Prior art keywords
levocarnitine
erythritol
sorbitan
mitigate
glycerin
Prior art date
Application number
CL2014000863A
Other languages
English (en)
Inventor
Joseph G Vehige
Peter A Simmons
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47040830&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014000863(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of CL2014000863A1 publication Critical patent/CL2014000863A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/745—Polymers of hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CL2014000863A 2011-10-06 2014-04-07 Una composicion oftalmologica que comprende monooleato de polioxietileno (80) sorbitan, carboximetilcelulosa sodica, glicerina, acido borico, polimero reticulado de acrilatos/acrilato de alquilo c10-30, aceite de ricino, eritritol, levocarnitina, hidroxido de sodio y agua; y su uso para tratar, mitigar o prevenir el sindrome del ojo seco. CL2014000863A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161544151P 2011-10-06 2011-10-06

Publications (1)

Publication Number Publication Date
CL2014000863A1 true CL2014000863A1 (es) 2014-08-29

Family

ID=47040830

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014000863A CL2014000863A1 (es) 2011-10-06 2014-04-07 Una composicion oftalmologica que comprende monooleato de polioxietileno (80) sorbitan, carboximetilcelulosa sodica, glicerina, acido borico, polimero reticulado de acrilatos/acrilato de alquilo c10-30, aceite de ricino, eritritol, levocarnitina, hidroxido de sodio y agua; y su uso para tratar, mitigar o prevenir el sindrome del ojo seco.

Country Status (18)

Country Link
US (8) US8957048B2 (es)
EP (1) EP2765987A1 (es)
JP (1) JP6209163B2 (es)
CN (2) CN108175778B (es)
AU (1) AU2012318556B2 (es)
BR (1) BR112014008314B1 (es)
CA (1) CA2851398C (es)
CL (1) CL2014000863A1 (es)
HK (1) HK1201042A1 (es)
IL (1) IL231970A (es)
MX (1) MX372990B (es)
MY (1) MY169328A (es)
PH (1) PH12014500767A1 (es)
RU (1) RU2651046C2 (es)
SG (1) SG11201401323PA (es)
TW (1) TWI642432B (es)
WO (1) WO2013052760A1 (es)
ZA (1) ZA201404121B (es)

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Publication number Publication date
US10105386B2 (en) 2018-10-23
BR112014008314B1 (pt) 2022-04-05
RU2014122945A (ru) 2015-12-20
NZ625799A (en) 2016-09-30
ZA201404121B (en) 2016-07-27
MY169328A (en) 2019-03-21
IL231970A (en) 2016-12-29
US20220096523A1 (en) 2022-03-31
PH12014500767A1 (en) 2015-10-23
BR112014008314A2 (pt) 2017-04-11
EP2765987A1 (en) 2014-08-20
JP6209163B2 (ja) 2017-10-04
CN108175778A (zh) 2018-06-19
TW201316984A (zh) 2013-05-01
RU2651046C2 (ru) 2018-04-18
US20210000859A1 (en) 2021-01-07
US8957048B2 (en) 2015-02-17
AU2012318556B2 (en) 2017-10-26
CN108175778B (zh) 2024-07-05
HK1201042A1 (en) 2015-08-21
MX2014004203A (es) 2014-10-17
WO2013052760A1 (en) 2013-04-11
US20190247419A1 (en) 2019-08-15
MX372990B (es) 2020-04-28
US20130090308A1 (en) 2013-04-11
US20240122963A1 (en) 2024-04-18
TWI642432B (zh) 2018-12-01
US20150196582A1 (en) 2015-07-16
US20250281521A1 (en) 2025-09-11
CA2851398A1 (en) 2013-04-11
US20140242022A1 (en) 2014-08-28
SG11201401323PA (en) 2014-08-28
CA2851398C (en) 2019-11-05
CN103974694A (zh) 2014-08-06
JP2014528452A (ja) 2014-10-27
IL231970A0 (en) 2014-05-28
AU2012318556A1 (en) 2014-07-31

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