CL2014000909A1 - Una tableta que comprende 7-[4-(4-benzo[b]tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona o una sal de ella como ingrediente activo; y metodo para producirla. - Google Patents

Una tableta que comprende 7-[4-(4-benzo[b]tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona o una sal de ella como ingrediente activo; y metodo para producirla.

Info

Publication number: CL2014000909A1
Authority: CL; Chile
Prior art keywords: quinolin; thiophen; piperazin; benzo; butoxy
Prior art date: 2011-10-14

Application number

CL2014000909A

Other languages

English (en)

Inventor

Yoshiharu Inque

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-10-14

Filing date

2014-04-10

Publication date

2014-11-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48081918&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014000909(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-04-10 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

2014-11-21 Publication of CL2014000909A1 publication Critical patent/CL2014000909A1/es

Links

239000004480 active ingredient Substances 0.000 title 1
ZKIAIYBUSXZPLP-UHFFFAOYSA-N brexpiprazole Chemical compound C1=C2NC(=O)C=CC2=CC=C1OCCCCN(CC1)CCN1C1=CC=CC2=C1C=CS2 ZKIAIYBUSXZPLP-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Inorganic Chemistry (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Supply Of Fluid Materials To The Packaging Location (AREA)
Basic Packing Technique (AREA)

CL2014000909A 2011-10-14 2014-04-10 Una tableta que comprende 7-[4-(4-benzo[b]tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona o una sal de ella como ingrediente activo; y metodo para producirla. CL2014000909A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2011227057		2011-10-14

Publications (1)

Publication Number	Publication Date
CL2014000909A1 true CL2014000909A1 (es)	2014-11-21

Family

ID=48081918

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2014000909A CL2014000909A1 (es)	2011-10-14	2014-04-10	Una tableta que comprende 7-[4-(4-benzo[b]tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona o una sal de ella como ingrediente activo; y metodo para producirla.

Country Status (34)

Country	Link
US (8)	US20140234417A1 (es)
EP (1)	EP2767285B2 (es)
JP (2)	JP6084161B2 (es)
KR (1)	KR102072371B1 (es)
CN (2)	CN103889425B (es)
AP (1)	AP2014007564A0 (es)
AR (1)	AR088319A1 (es)
AU (1)	AU2012321723C1 (es)
BR (1)	BR112014008603A2 (es)
CA (1)	CA2851588C (es)
CL (1)	CL2014000909A1 (es)
CO (1)	CO6950480A2 (es)
CY (1)	CY1122460T1 (es)
DK (1)	DK2767285T4 (es)
EA (1)	EA032930B1 (es)
ES (1)	ES2762479T5 (es)
FI (1)	FI2767285T4 (es)
HR (1)	HRP20200037T4 (es)
HU (1)	HUE047493T2 (es)
IL (1)	IL231513B (es)
IN (1)	IN2014DN02055A (es)
JO (1)	JO3753B1 (es)
LT (1)	LT2767285T (es)
MX (1)	MX376092B (es)
MY (1)	MY173370A (es)
PH (1)	PH12014500607A1 (es)
PL (1)	PL2767285T5 (es)
PT (1)	PT2767285T (es)
SG (2)	SG2014013783A (es)
SI (1)	SI2767285T2 (es)
TW (1)	TWI634908B (es)
UA (1)	UA114411C2 (es)
WO (1)	WO2013054872A1 (es)
ZA (1)	ZA201402333B (es)

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JOP20200109A1 (ar)	2012-04-23	2017-06-16	Otsuka Pharma Co Ltd	مستحضر قابل للحقن
JP5936732B1 (ja) *	2015-03-05	2016-06-22	日本カラコン合同会社	フィルムコーティング組成物
CN105106142B (zh) *	2015-09-22	2018-05-22	成都欣捷高新技术开发有限公司	一种含有依匹哌唑的冻干口服制剂及其制备方法
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EP3501506B1 (en)	2017-12-19	2019-10-09	Alfred E. Tiefenbacher (GmbH & Co. KG)	Pharmaceutical tablet composition comprising brexpiprazole
EP3545950A1 (en)	2018-03-26	2019-10-02	Adamed sp. z o.o.	Pharmaceutical composition comprising brexpiprazole
WO2021029020A1 (ja) *	2019-08-13	2021-02-18	大塚製薬株式会社	経口医薬組成物
WO2021095092A1 (ja) *	2019-11-11	2021-05-20	大塚製薬株式会社	口腔内崩壊錠
CN112168794A (zh) *	2020-10-27	2021-01-05	浙江诺得药业有限公司	一种布瑞哌唑片的制备方法
WO2022218358A1 (zh) *	2021-04-13	2022-10-20	上海博志研新药物技术有限公司	一种布瑞哌唑物口腔薄膜剂、其制备方法及应用
EP4374856A1 (en)	2022-11-23	2024-05-29	Sanovel Ilac Sanayi Ve Ticaret A.S.	A process for tablets comprising brexpiprazole

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JO3753B1 (ar) *	2011-10-14	2021-01-31	Otsuka Pharma Co Ltd	قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه

2012
- 2012-10-04 JO JOP/2012/0301A patent/JO3753B1/ar active
- 2012-10-09 TW TW101137267A patent/TWI634908B/zh active
- 2012-10-12 AU AU2012321723A patent/AU2012321723C1/en active Active
- 2012-10-12 SG SG2014013783A patent/SG2014013783A/en unknown
- 2012-10-12 CN CN201280050586.1A patent/CN103889425B/zh active Active
- 2012-10-12 MX MX2014004135A patent/MX376092B/es active IP Right Grant
- 2012-10-12 BR BR112014008603A patent/BR112014008603A2/pt not_active Application Discontinuation
- 2012-10-12 UA UAA201405029A patent/UA114411C2/uk unknown
- 2012-10-12 CN CN201710266863.7A patent/CN107397730A/zh active Pending
- 2012-10-12 KR KR1020147010656A patent/KR102072371B1/ko active Active
- 2012-10-12 PH PH1/2014/500607A patent/PH12014500607A1/en unknown
- 2012-10-12 CA CA2851588A patent/CA2851588C/en active Active
- 2012-10-12 AR ARP120103801A patent/AR088319A1/es not_active Application Discontinuation
- 2012-10-12 EA EA201490783A patent/EA032930B1/ru active Protection Beyond IP Right Term
- 2012-10-12 EP EP12840025.6A patent/EP2767285B2/en active Active
- 2012-10-12 HU HUE12840025A patent/HUE047493T2/hu unknown
- 2012-10-12 FI FIEP12840025.6T patent/FI2767285T4/fi active
- 2012-10-12 HR HRP20200037TT patent/HRP20200037T4/hr unknown
- 2012-10-12 US US14/351,325 patent/US20140234417A1/en not_active Abandoned
- 2012-10-12 MY MYPI2014700632A patent/MY173370A/en unknown
- 2012-10-12 PT PT128400256T patent/PT2767285T/pt unknown
- 2012-10-12 ES ES12840025T patent/ES2762479T5/es active Active
- 2012-10-12 PL PL12840025.6T patent/PL2767285T5/pl unknown
- 2012-10-12 SI SI201231718T patent/SI2767285T2/sl unknown
- 2012-10-12 SG SG10201608412SA patent/SG10201608412SA/en unknown
- 2012-10-12 JP JP2013538582A patent/JP6084161B2/ja active Active
- 2012-10-12 LT LTEP12840025.6T patent/LT2767285T/lt unknown
- 2012-10-12 AP AP2014007564A patent/AP2014007564A0/xx unknown
- 2012-10-12 DK DK12840025.6T patent/DK2767285T4/da active
- 2012-10-12 WO PCT/JP2012/076415 patent/WO2013054872A1/ja not_active Ceased
2014
- 2014-03-13 IL IL231513A patent/IL231513B/en active IP Right Grant
- 2014-03-19 IN IN2055DEN2014 patent/IN2014DN02055A/en unknown
- 2014-03-28 ZA ZA2014/02333A patent/ZA201402333B/en unknown
- 2014-04-10 CL CL2014000909A patent/CL2014000909A1/es unknown
- 2014-05-07 CO CO14098041A patent/CO6950480A2/es unknown
2016
- 2016-02-09 US US15/019,874 patent/US20160158227A1/en not_active Abandoned
2017
- 2017-01-20 JP JP2017008854A patent/JP2017088610A/ja active Pending
- 2017-02-27 US US15/444,113 patent/US20170165258A1/en not_active Abandoned
- 2017-09-22 US US15/713,427 patent/US10307419B2/en active Active
2019
- 2019-04-12 US US16/383,488 patent/US20190240215A1/en not_active Abandoned
2020
- 2020-01-08 CY CY20201100009T patent/CY1122460T1/el unknown
- 2020-10-01 US US17/061,394 patent/US20210023078A1/en not_active Abandoned
2022
- 2022-03-07 US US17/653,838 patent/US20220331311A1/en not_active Abandoned
2023
- 2023-12-18 US US18/543,053 patent/US20240277703A1/en active Pending

Also Published As

Publication number	Publication date
WO2013054872A1 (ja)	2013-04-18
DK2767285T3 (da)	2020-01-27
DK2767285T4 (da)	2025-04-22
CA2851588A1 (en)	2013-04-18
CA2851588C (en)	2019-07-02
KR102072371B1 (ko)	2020-02-03
PL2767285T5 (pl)	2025-06-02
MX376092B (es)	2025-03-07
SG10201608412SA (en)	2016-12-29
HUE047493T2 (hu)	2020-04-28
US20220331311A1 (en)	2022-10-20
BR112014008603A2 (pt)	2017-04-18
ZA201402333B (en)	2015-07-29
US20240277703A1 (en)	2024-08-22
JP6084161B2 (ja)	2017-02-22
AU2012321723A1 (en)	2014-05-15
MX2014004135A (es)	2014-07-24
US20180008600A1 (en)	2018-01-11
FI2767285T4 (fi)	2025-05-08
TWI634908B (zh)	2018-09-11
AU2012321723B2 (en)	2017-07-20
US10307419B2 (en)	2019-06-04
PL2767285T3 (pl)	2020-04-30
EA201490783A1 (ru)	2014-07-30
EP2767285B1 (en)	2019-11-27
MY173370A (en)	2020-01-21
NZ622639A (en)	2015-11-27
US20140234417A1 (en)	2014-08-21
US20160158227A1 (en)	2016-06-09
HRP20200037T4 (hr)	2025-05-23
PT2767285T (pt)	2020-01-21
CN107397730A (zh)	2017-11-28
JPWO2013054872A1 (ja)	2015-03-30
PH12014500607A1 (en)	2014-04-21
JP2017088610A (ja)	2017-05-25
LT2767285T (lt)	2020-02-10
IL231513A0 (en)	2014-04-30
IN2014DN02055A (es)	2015-05-15
EP2767285B2 (en)	2025-02-19
US20210023078A1 (en)	2021-01-28
US20170165258A1 (en)	2017-06-15
SI2767285T2 (sl)	2025-06-30
AP2014007564A0 (en)	2014-04-30
AU2012321723C1 (en)	2017-11-02
HRP20200037T1 (hr)	2020-03-20
TW201318651A (zh)	2013-05-16
IL231513B (en)	2020-01-30
EP2767285A1 (en)	2014-08-20
ES2762479T3 (es)	2020-05-25
JO3753B1 (ar)	2021-01-31
AR088319A1 (es)	2014-05-28
KR20140075754A (ko)	2014-06-19
ES2762479T5 (en)	2025-05-30
EP2767285A4 (en)	2015-03-11
EA032930B1 (ru)	2019-08-30
US20190240215A1 (en)	2019-08-08
CN103889425B (zh)	2018-08-03
SI2767285T1 (sl)	2020-03-31
UA114411C2 (uk)	2017-06-12
CY1122460T1 (el)	2021-01-27
CO6950480A2 (es)	2014-05-20
SG2014013783A (en)	2014-06-27
CN103889425A (zh)	2014-06-25

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