CL2014001776A1 - Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis. - Google Patents

Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis.

Info

Publication number
CL2014001776A1
CL2014001776A1 CL2014001776A CL2014001776A CL2014001776A1 CL 2014001776 A1 CL2014001776 A1 CL 2014001776A1 CL 2014001776 A CL2014001776 A CL 2014001776A CL 2014001776 A CL2014001776 A CL 2014001776A CL 2014001776 A1 CL2014001776 A1 CL 2014001776A1
Authority
CL
Chile
Prior art keywords
bexarotene
corticosteroid
psoriasis
prevention
carrier
Prior art date
Application number
CL2014001776A
Other languages
English (en)
Inventor
Fritjof Evers
Henning Mallwitz
Christoph Willers
Sabine Fielhauer
Hagen Trommer
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48781060&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2014001776(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP12000077.3A external-priority patent/EP2612665A1/en
Application filed by Almirall Sa filed Critical Almirall Sa
Publication of CL2014001776A1 publication Critical patent/CL2014001776A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CL2014001776A 2012-01-09 2014-07-02 Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis. CL2014001776A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12000077.3A EP2612665A1 (en) 2012-01-09 2012-01-09 Topical pharmaceutical compositions comprising bexarotene and a corticosteroide
US201261585786P 2012-01-12 2012-01-12
US201261598095P 2012-02-13 2012-02-13
EP12000909 2012-02-13

Publications (1)

Publication Number Publication Date
CL2014001776A1 true CL2014001776A1 (es) 2014-08-29

Family

ID=48781060

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014001776A CL2014001776A1 (es) 2012-01-09 2014-07-02 Composicion farmaceutica topica que comprende: a) bexaroteno, b) al menos 1 corticosteroide y c) un portador o vehiculo; uso para el tratamiento o la prevencion de trastornos de la piel, como psoriasis.

Country Status (21)

Country Link
US (1) US20140349981A1 (es)
EP (1) EP2802321A1 (es)
JP (1) JP2015503573A (es)
KR (1) KR20140107370A (es)
CN (1) CN104053437A (es)
AU (1) AU2012365658A1 (es)
BR (1) BR112014015578A8 (es)
CA (1) CA2857207A1 (es)
CL (1) CL2014001776A1 (es)
CO (1) CO7000772A2 (es)
CR (1) CR20140326A (es)
EA (1) EA201400806A1 (es)
GT (1) GT201400146A (es)
HK (1) HK1198423A1 (es)
IL (1) IL232765A0 (es)
MX (1) MX2014007300A (es)
PE (1) PE20142375A1 (es)
PH (1) PH12014501573A1 (es)
SG (1) SG11201403762PA (es)
WO (1) WO2013104399A1 (es)
ZA (1) ZA201403483B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2909884T3 (es) 2013-08-20 2022-05-10 Univ Washington Through Its Center For Commercialization Inhibidores nuevos y específicos de la hidroxilasa del ácido retinoico del citocromo P450 26
KR102643849B1 (ko) 2015-06-18 2024-03-07 밸리언트 파마슈티컬즈 노오쓰 아메리카 엘엘씨 건선을 치료하기 위한 코르티코스테로이드 및 레티노이드를 포함하는 국소 조성물
US11311482B2 (en) 2017-05-12 2022-04-26 Bausch Health Us, Llc Topical compositions and methods for treating skin diseases
EP3856155A4 (en) * 2018-09-28 2022-10-05 Joel Studin DELIVERY OF STEROIDS AND LARGE MOLECULES THROUGH THE PORE
EP3870150A1 (en) * 2018-10-26 2021-09-01 Viramal Limited Mucoadhesive gel composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0969847A1 (en) 1997-02-20 2000-01-12 Allergan Sales, Inc. Tazarotene and corticosteroid treatment for psoriasis
CN1210034C (zh) * 2002-12-06 2005-07-13 重庆华邦制药股份有限公司 治疗银屑病的药物组合物
CN1210035C (zh) 2003-09-29 2005-07-13 中国医学科学院皮肤病研究所 治疗银屑病的复方外用药物

Also Published As

Publication number Publication date
CR20140326A (es) 2015-01-16
IL232765A0 (en) 2014-07-31
HK1198423A1 (en) 2015-04-24
SG11201403762PA (en) 2014-07-30
JP2015503573A (ja) 2015-02-02
EA201400806A1 (ru) 2015-02-27
PE20142375A1 (es) 2015-01-11
US20140349981A1 (en) 2014-11-27
EP2802321A1 (en) 2014-11-19
AU2012365658A1 (en) 2014-07-03
ZA201403483B (en) 2015-06-24
MX2014007300A (es) 2014-07-28
PH12014501573A1 (en) 2014-10-08
CA2857207A1 (en) 2013-07-18
GT201400146A (es) 2015-10-12
BR112014015578A8 (pt) 2017-07-04
CN104053437A (zh) 2014-09-17
CO7000772A2 (es) 2014-07-21
WO2013104399A1 (en) 2013-07-18
KR20140107370A (ko) 2014-09-04
BR112014015578A2 (pt) 2017-06-13

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