CL2015003780A1 - Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticas aceptables; composiciones farmáceuticas; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes. - Google Patents
Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticas aceptables; composiciones farmáceuticas; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes.Info
- Publication number
- CL2015003780A1 CL2015003780A1 CL2015003780A CL2015003780A CL2015003780A1 CL 2015003780 A1 CL2015003780 A1 CL 2015003780A1 CL 2015003780 A CL2015003780 A CL 2015003780A CL 2015003780 A CL2015003780 A CL 2015003780A CL 2015003780 A1 CL2015003780 A1 CL 2015003780A1
- Authority
- CL
- Chile
- Prior art keywords
- bacterial
- pyrimido
- isoquinolin
- tautomers
- farm
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title 1
- -1 Pyrimido-isoquinolin-quinone derivative compounds Chemical class 0.000 title 1
- 230000001580 bacterial effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2015003780A CL2015003780A1 (es) | 2015-12-30 | 2015-12-30 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticas aceptables; composiciones farmáceuticas; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes. |
| MX2018008192A MX383627B (es) | 2015-12-30 | 2016-12-29 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticamente aceptables; composición farmaceutica; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes. |
| PCT/CL2016/050080 WO2017113031A1 (es) | 2015-12-30 | 2016-12-29 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticamente aceptables; composición farmacéutica; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes |
| ES16880235T ES2951489T3 (es) | 2015-12-30 | 2016-12-29 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticamente aceptables; composición farmacéutica; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes |
| EP16880235.3A EP3404026B1 (en) | 2015-12-30 | 2016-12-29 | Pyrimido-isoquinolin-quinone derivative compounds, and pharmaceutically acceptable salts, isomers and tautomers thereof; pharmaceutical composition; preparation method; and use thereof in the treatment of diseases caused by bacteria and multidrug-resistant bacteria |
| US16/067,033 US11390622B2 (en) | 2015-12-30 | 2016-12-29 | Pyrimido-isoquinolin-quinone derivative compounds, and pharmaceutically acceptable salts, isomers and tautomers thereof; pharmaceutical composition; preparation method; and use thereof in the treatment of diseases caused by bacteria and multidrug-resistant bacteria |
| CN201680081761.1A CN109121411B (zh) | 2015-12-30 | 2016-12-29 | 嘧啶并-异喹啉-醌衍生的化合物、含有它们的药物组合物和它们在细菌性疾病治疗中的用途 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2015003780A CL2015003780A1 (es) | 2015-12-30 | 2015-12-30 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticas aceptables; composiciones farmáceuticas; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2015003780A1 true CL2015003780A1 (es) | 2016-09-16 |
Family
ID=57234031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2015003780A CL2015003780A1 (es) | 2015-12-30 | 2015-12-30 | Compuestos derivados pirimido-isoquinolin-quinonas, sus sales, isomeros, tautomeros farmacéuticas aceptables; composiciones farmáceuticas; procedimiento de preparación; y su uso en el tratamiento de enfermedades bacterianas y bacterianas multirresistentes. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11390622B2 (es) |
| EP (1) | EP3404026B1 (es) |
| CN (1) | CN109121411B (es) |
| CL (1) | CL2015003780A1 (es) |
| ES (1) | ES2951489T3 (es) |
| MX (1) | MX383627B (es) |
| WO (1) | WO2017113031A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118903076B (zh) * | 2024-07-23 | 2025-07-15 | 佛山市南海区第四人民医院 | 氢醌类衍生物在抑制肺炎克雷伯菌活性及制备抗肺炎克雷伯菌药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03009894A (es) | 2001-06-19 | 2004-02-17 | Warner Lambert Co | Agentes antibacterianos. |
| DE10341614A1 (de) | 2003-09-10 | 2005-04-28 | Basf Ag | Verfahren zur Herstellung von Xylylendiamin (XDA) |
| EP1687296A1 (en) | 2003-11-18 | 2006-08-09 | Warner-Lambert Company LLC | Antibacterial aminoquinazolidinedione derivatives |
-
2015
- 2015-12-30 CL CL2015003780A patent/CL2015003780A1/es unknown
-
2016
- 2016-12-29 ES ES16880235T patent/ES2951489T3/es active Active
- 2016-12-29 MX MX2018008192A patent/MX383627B/es unknown
- 2016-12-29 US US16/067,033 patent/US11390622B2/en active Active
- 2016-12-29 EP EP16880235.3A patent/EP3404026B1/en active Active
- 2016-12-29 CN CN201680081761.1A patent/CN109121411B/zh not_active Expired - Fee Related
- 2016-12-29 WO PCT/CL2016/050080 patent/WO2017113031A1/es not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MX383627B (es) | 2025-03-14 |
| CN109121411A (zh) | 2019-01-01 |
| US20190367505A1 (en) | 2019-12-05 |
| US11390622B2 (en) | 2022-07-19 |
| ES2951489T3 (es) | 2023-10-23 |
| WO2017113031A1 (es) | 2017-07-06 |
| EP3404026B1 (en) | 2023-03-15 |
| EP3404026A4 (en) | 2019-11-27 |
| MX2018008192A (es) | 2018-11-09 |
| EP3404026A1 (en) | 2018-11-21 |
| CN109121411B (zh) | 2021-01-08 |
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