CL2016002342A1 - Una pasta implantable y su uso. - Google Patents

Una pasta implantable y su uso.

Info

Publication number
CL2016002342A1
CL2016002342A1 CL2016002342A CL2016002342A CL2016002342A1 CL 2016002342 A1 CL2016002342 A1 CL 2016002342A1 CL 2016002342 A CL2016002342 A CL 2016002342A CL 2016002342 A CL2016002342 A CL 2016002342A CL 2016002342 A1 CL2016002342 A1 CL 2016002342A1
Authority
CL
Chile
Prior art keywords
molecular weight
weight
polyethylene glycol
mol
bioactive glass
Prior art date
Application number
CL2016002342A
Other languages
English (en)
Inventor
Lorenzo Drago
Carlo Luca Romano
Jimmy Lucchesi
Fredrik Ollila
Original Assignee
Bonalive Biomaterials Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bonalive Biomaterials Oy filed Critical Bonalive Biomaterials Oy
Publication of CL2016002342A1 publication Critical patent/CL2016002342A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Polymers & Plastics (AREA)

Abstract

<p>Una pasta implantable CARACTERIZADA porque comprende un polvo de vidrio bioactivo que tiene una distribución de tamaño de 0.5 a 45 pm, en una cantidad de 10-30% en peso del peso total del vidrio bioactivo gránulos de vidrio bioactivo que tienen una distribuciOn de tamano entre 100 y 4000 pm, en una cantidad de 90-70 % en peso del peso total del vidrio activo en Ia pasta polietilenglicol de bajo peso molecular que tiene un rango en peso molecular de 200 a 700 g/mol, polietilenglicol de peso molecular media que tiere un rango en peso molecular de 700 a 2500 g/mol, polietilenglicol de alto peso molecular que tiene un rango en peso molecular de 2500 a 8000 g/mol, y glicerol, en donde Ia composición del vidrio bioactivo es de 45 a 55% en peso de SiO2, de 20 a 25% en peso de Na2O, de 18 a 25% en peso de CaO y de 3 a 6% en peso de P2O5, con Ia salvedad de que el peso molecular del polietilenglicol de baja peso molecular y del polietilenglicol de peso molecular medio difieran entre si por al menos 80 g/mol y que el peso molecular del polietilenglicol de peso molecular medio y del polietilenglicol de alto peso molecular difieran entre si par al menos 300 g/mol.</p>
CL2016002342A 2014-03-17 2016-09-16 Una pasta implantable y su uso. CL2016002342A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14160184.9A EP2875832B1 (en) 2014-03-17 2014-03-17 Implantable paste and its use

Publications (1)

Publication Number Publication Date
CL2016002342A1 true CL2016002342A1 (es) 2017-01-06

Family

ID=50280251

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016002342A CL2016002342A1 (es) 2014-03-17 2016-09-16 Una pasta implantable y su uso.

Country Status (16)

Country Link
US (1) US12364788B2 (es)
EP (1) EP2875832B1 (es)
JP (1) JP6417424B2 (es)
KR (1) KR102414533B1 (es)
CN (1) CN106132451B (es)
AU (1) AU2015233693B2 (es)
BR (1) BR112016018806B1 (es)
CA (1) CA2940280C (es)
CL (1) CL2016002342A1 (es)
ES (1) ES2588395T3 (es)
MX (1) MX351005B (es)
MY (1) MY177743A (es)
PE (1) PE20170096A1 (es)
PL (1) PL2875832T3 (es)
RU (1) RU2678590C2 (es)
WO (1) WO2015140088A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0811530B1 (pt) 2007-05-14 2019-01-02 Research Foundation Of State Univ Of New York composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície
CN108114312A (zh) * 2018-02-26 2018-06-05 王由 一种可塑性45s5生物活性玻璃及其制备方法
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
US11090412B2 (en) 2018-12-21 2021-08-17 Zavation Medical Products Llc Bone repair composition and kit
FR3116713B1 (fr) * 2020-12-02 2023-02-10 Produits Dentaires Pierre Rolland Produit dentaire pour la formation d’un ciment endodontique
CN114984307B (zh) * 2021-03-02 2023-08-15 中科硅骨(东莞)医疗器械有限公司 一种可塑形骨修复材料及其制备方法
CN113521376B (zh) * 2021-07-22 2022-08-30 赛克赛斯生物科技股份有限公司 一种外科密封剂试剂盒及其在脑、脊柱外科手术中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290558A (en) * 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US6190643B1 (en) * 1999-03-02 2001-02-20 Patricia Stoor Method for reducing the viability of detrimental oral microorganisms in an individual, and for prevention and/or treatment of diseases caused by such microorganisms; and whitening and/or cleaning of an individual's teeth
TW200518767A (en) 2003-09-12 2005-06-16 Wyeth Corp Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
WO2007068489A2 (en) * 2005-12-14 2007-06-21 Scil Technology Gmbh A moldable biomaterial for bone regeneration
US20090324668A1 (en) * 2006-06-28 2009-12-31 Ilkka Kangasniemi Implant, its uses and methods for making it
US8288344B2 (en) * 2007-03-15 2012-10-16 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
EP2448607A1 (en) 2009-06-29 2012-05-09 BonAlive Biomaterials Oy A bioactive glass for use in conditions relating to bone infections
EP2322134B1 (en) 2009-11-12 2012-09-12 BonAlive Biomaterials Oy Implantable paste and its use

Also Published As

Publication number Publication date
ES2588395T3 (es) 2016-11-02
JP2017512524A (ja) 2017-05-25
EP2875832A1 (en) 2015-05-27
KR102414533B1 (ko) 2022-06-29
CN106132451B (zh) 2017-11-28
RU2016140417A (ru) 2018-04-20
RU2678590C2 (ru) 2019-01-30
US12364788B2 (en) 2025-07-22
PL2875832T3 (pl) 2016-12-30
KR20160134651A (ko) 2016-11-23
BR112016018806B1 (pt) 2021-01-19
RU2016140417A3 (es) 2018-08-22
US20170072098A1 (en) 2017-03-16
AU2015233693B2 (en) 2016-11-03
PE20170096A1 (es) 2017-03-09
MY177743A (en) 2020-09-23
JP6417424B2 (ja) 2018-11-07
CN106132451A (zh) 2016-11-16
CA2940280C (en) 2017-04-18
MX351005B (es) 2017-09-27
MX2016012003A (es) 2016-12-07
CA2940280A1 (en) 2015-09-24
EP2875832B1 (en) 2016-05-25
WO2015140088A1 (en) 2015-09-24

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