CL2016002906A1 - Secuencia polinucleotídica recombinante para producir astaxanthin y sus usos - Google Patents
Secuencia polinucleotídica recombinante para producir astaxanthin y sus usosInfo
- Publication number
- CL2016002906A1 CL2016002906A1 CL2016002906A CL2016002906A CL2016002906A1 CL 2016002906 A1 CL2016002906 A1 CL 2016002906A1 CL 2016002906 A CL2016002906 A CL 2016002906A CL 2016002906 A CL2016002906 A CL 2016002906A CL 2016002906 A1 CL2016002906 A1 CL 2016002906A1
- Authority
- CL
- Chile
- Prior art keywords
- recombinant polynucleotide
- astaxanthin
- polynucleotide sequence
- produce astaxanthin
- higher level
- Prior art date
Links
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 title abstract 4
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 title abstract 4
- 229940022405 astaxanthin Drugs 0.000 title abstract 4
- 235000013793 astaxanthin Nutrition 0.000 title abstract 4
- 239000001168 astaxanthin Substances 0.000 title abstract 4
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000037353 metabolic pathway Effects 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Epoxy Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
<p>En este documento se revelan secuencias de polinucleótidos recombinantes, vectores, células huésped y métodos para producir astaxantina. La secuencia de polinucleótido recombinante es diseñada para proporcionar un nivel superior de precursores de astaxantina mediante una vía metabólica más corta, y por lo tanto alcanza un mayor nivel de productos finales (por ejemplo, astaxantina) con forma estereoisomérica deseada y/o forma esterificada.</p>
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461994828P | 2014-05-16 | 2014-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2016002906A1 true CL2016002906A1 (es) | 2018-03-16 |
Family
ID=54480945
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2016002906A CL2016002906A1 (es) | 2014-05-16 | 2016-11-15 | Secuencia polinucleotídica recombinante para producir astaxanthin y sus usos |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20170137792A1 (es) |
| EP (2) | EP3460044B1 (es) |
| JP (2) | JP2017515512A (es) |
| CN (2) | CN111500599A (es) |
| CA (2) | CA3109156C (es) |
| CL (1) | CL2016002906A1 (es) |
| TW (1) | TWI681052B (es) |
| WO (1) | WO2015176054A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11124819B2 (en) * | 2017-03-15 | 2021-09-21 | The Regents Of The University Of California | Genes involved in astaxanthin biosynthesis |
| HRP20230560T1 (hr) * | 2019-01-29 | 2023-08-18 | Clariant Produkte (Deutschland) Gmbh | Kimerni promotor za upotrebu u metaboličkom inženjeringu |
| CN110283867A (zh) * | 2019-05-24 | 2019-09-27 | 华南理工大学 | 一种利用佐夫色绿藻生产虾青素的方法 |
| CN114410523B (zh) * | 2022-01-20 | 2023-10-31 | 中国农业科学院茶叶研究所 | 一种制备红茶菌的菌种组合及其应用 |
| WO2024151157A2 (en) * | 2023-01-10 | 2024-07-18 | Universiti Putra Malaysia | Astaxanthin-expressing yeast as feed additive for aquaculture |
| CN117604060A (zh) * | 2024-01-24 | 2024-02-27 | 逢时(青岛)海洋科技有限公司 | 一种基于固定化胆固醇酯酶的游离虾青素及其制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2216027T3 (es) * | 1995-06-09 | 2004-10-16 | Dsm Ip Assets B.V. | Produccion de carotenoides fermentativos. |
| DE69633343T2 (de) * | 1995-12-22 | 2005-09-22 | Dsm Ip Assets B.V. | Verbesserte verfahren zur transformation von phaffiastämmen,transformierte phaffiastämme auf diese weise erhaltend, und rekominante dns in besagtem verfahren verwendbar |
| DE60005871T2 (de) * | 1999-03-09 | 2004-05-06 | Dsm Ip Assets B.V. | Astaxanthin Synthetase |
| DE19916140A1 (de) * | 1999-04-09 | 2000-10-12 | Basf Ag | Carotinhydroxylase und Verfahren zur Herstellung von Xanthophyllderivaten |
| JP2004033070A (ja) * | 2002-07-01 | 2004-02-05 | Yamaha Motor Co Ltd | 緑藻ヘマトコッカスへの外来遺伝子導入方法 |
| DE10253112A1 (de) * | 2002-11-13 | 2004-06-03 | Sungene Gmbh & Co. Kgaa | Verfahren zur Herstellung von Ketocarotinoiden in genetisch veränderten Organismen |
| DE10238980A1 (de) * | 2002-08-20 | 2004-03-04 | Sungene Gmbh & Co. Kgaa | Verfahren zur Herstellung von Ketocarotinoiden in Blütenblättern von Pflanzen |
| DE10258971A1 (de) * | 2002-12-16 | 2004-07-01 | Sungene Gmbh & Co. Kgaa | Verwendung von astaxanthinhaltigen Pflanzen oder Pflanzenteilen der Gattung Tagetes als Futtermittel |
| DE10300649A1 (de) * | 2003-01-09 | 2004-07-22 | Basf Ag | Verfahren zur Herstellung von Ketocarotinoiden durch Kultivierung von genetisch veränderten Organismen |
| DE102004007624A1 (de) | 2004-02-17 | 2005-09-15 | Sungene Gmbh & Co. Kgaa | Neue Ketolasen und Verfahren zur Herstellung von Ketocarotinoiden |
| CN103589650A (zh) * | 2005-03-18 | 2014-02-19 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| US20070157339A1 (en) * | 2006-01-04 | 2007-07-05 | Cunningham Francis X Jr | Biochemical route to astaxanthin |
| US8373023B2 (en) * | 2006-04-21 | 2013-02-12 | University Of Maryland | Biochemical route to astaxanthin |
| CN101516906B (zh) * | 2006-07-21 | 2013-11-06 | 诺维信股份有限公司 | 提高具有生物学活性之多肽的分泌的方法 |
| EP2048939A4 (en) | 2006-08-17 | 2010-04-28 | Monsanto Technology Llc | TRANSGENIC PLANTS WITH ADVANCED AGRONOMIC CHARACTERISTICS |
| WO2008042338A2 (en) * | 2006-09-28 | 2008-04-10 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| US7935156B2 (en) * | 2006-11-21 | 2011-05-03 | Amyris Biotechnologies, Inc. | Jet fuel compositions and methods of making and using same |
| US8846374B2 (en) * | 2006-12-12 | 2014-09-30 | E I Du Pont De Nemours And Company | Carotenoid production in a recombinant oleaginous yeast |
| WO2008148131A1 (en) * | 2007-05-31 | 2008-12-04 | Novozymes, Inc. | Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same |
| CL2008001699A1 (es) * | 2008-06-09 | 2010-02-05 | Univ Chile | Secuencia de adn que codifica enzima con actividad citocromo p450 reductasa de x. dendrorhous; secuencia de polipeptido codificada; vector o plasmido; celula hesped; proceso de produccion de polipeptido; proceso de produccion de astaxantina desde beta-caroteno; composiciones, productos y/o formulaciones. |
| EP2199399A1 (en) * | 2008-12-17 | 2010-06-23 | BASF Plant Science GmbH | Production of ketocarotenoids in plants |
| WO2010079032A1 (en) * | 2008-12-17 | 2010-07-15 | Basf Plant Science Gmbh | Production of ketocarotenoids in plants |
| WO2011146833A1 (en) * | 2010-05-20 | 2011-11-24 | Evolva Inc. | Method of producing isoprenoid compounds in yeast |
| IN2014CN01129A (es) * | 2011-08-08 | 2015-04-10 | Evolva Sa | |
| AU2012359983B2 (en) * | 2011-12-28 | 2018-04-12 | Evogene Ltd. | Isolated polynucleotides and polypeptides, and methods of using same for increasing yield of plants |
| CN102888425B (zh) * | 2012-07-02 | 2015-02-25 | 中国科学院昆明植物研究所 | 利用转基因植物生产虾青素的方法 |
-
2015
- 2015-05-16 JP JP2017512890A patent/JP2017515512A/ja active Pending
- 2015-05-16 EP EP18187407.4A patent/EP3460044B1/en active Active
- 2015-05-16 CN CN202010106111.6A patent/CN111500599A/zh active Pending
- 2015-05-16 WO PCT/US2015/031273 patent/WO2015176054A2/en not_active Ceased
- 2015-05-16 CA CA3109156A patent/CA3109156C/en active Active
- 2015-05-16 CA CA2949381A patent/CA2949381A1/en not_active Abandoned
- 2015-05-16 EP EP15792264.2A patent/EP3143121A4/en not_active Withdrawn
- 2015-05-16 CN CN201580025469.3A patent/CN106795477A/zh active Pending
- 2015-05-18 TW TW104115715A patent/TWI681052B/zh active
-
2016
- 2016-11-15 CL CL2016002906A patent/CL2016002906A1/es unknown
- 2016-11-16 US US15/353,372 patent/US20170137792A1/en not_active Abandoned
-
2018
- 2018-11-26 US US16/200,269 patent/US10865397B2/en active Active
-
2019
- 2019-05-13 JP JP2019090969A patent/JP6964622B2/ja active Active
-
2020
- 2020-11-10 US US17/094,623 patent/US11781124B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TWI681052B (zh) | 2020-01-01 |
| EP3143121A4 (en) | 2018-02-28 |
| CA3109156A1 (en) | 2015-11-19 |
| CA3109156C (en) | 2023-08-15 |
| CN111500599A (zh) | 2020-08-07 |
| CA2949381A1 (en) | 2015-11-19 |
| WO2015176054A2 (en) | 2015-11-19 |
| EP3460044A1 (en) | 2019-03-27 |
| CN106795477A (zh) | 2017-05-31 |
| JP2019150047A (ja) | 2019-09-12 |
| US10865397B2 (en) | 2020-12-15 |
| US20170137792A1 (en) | 2017-05-18 |
| US11781124B2 (en) | 2023-10-10 |
| US20190144841A1 (en) | 2019-05-16 |
| US20210071153A1 (en) | 2021-03-11 |
| WO2015176054A3 (en) | 2016-01-07 |
| EP3143121A2 (en) | 2017-03-22 |
| JP6964622B2 (ja) | 2021-11-10 |
| TW201544593A (zh) | 2015-12-01 |
| JP2017515512A (ja) | 2017-06-15 |
| EP3460044B1 (en) | 2024-01-24 |
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