CL2017000151A1 - Pyridone derivatives - Google Patents

Pyridone derivatives

Info

Publication number
CL2017000151A1
CL2017000151A1 CL2017000151A CL2017000151A CL2017000151A1 CL 2017000151 A1 CL2017000151 A1 CL 2017000151A1 CL 2017000151 A CL2017000151 A CL 2017000151A CL 2017000151 A CL2017000151 A CL 2017000151A CL 2017000151 A1 CL2017000151 A1 CL 2017000151A1
Authority
CL
Chile
Prior art keywords
pyridone derivatives
compounds
pyridone
derivatives
compositions
Prior art date
Application number
CL2017000151A
Other languages
Spanish (es)
Inventor
Brian Alvin Johns
Emile Johann Velthuisen
Original Assignee
Viiv Healthcare Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53718072&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017000151(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Viiv Healthcare Uk Ltd filed Critical Viiv Healthcare Uk Ltd
Publication of CL2017000151A1 publication Critical patent/CL2017000151A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

<p>SE DAN A CONOCER COMPUESTOS DE LA FÓRMULA I  Y MÉTODOS PARA EL TRATAMIENTO DE INFECCIONES VIRALES, CON COMPOSICIONES QUE COMPRENDEN ESTOS COMPUESTOS.</p><p> FORMULA I COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS ARE KNOWN, WITH COMPOSITIONS THAT INCLUDE THESE COMPOUNDS. </p>

CL2017000151A 2014-07-21 2017-01-19 Pyridone derivatives CL2017000151A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462026782P 2014-07-21 2014-07-21

Publications (1)

Publication Number Publication Date
CL2017000151A1 true CL2017000151A1 (en) 2017-07-28

Family

ID=53718072

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017000151A CL2017000151A1 (en) 2014-07-21 2017-01-19 Pyridone derivatives

Country Status (16)

Country Link
US (1) US9802898B2 (en)
EP (1) EP3172189A1 (en)
JP (1) JP2017521455A (en)
KR (1) KR20170032324A (en)
CN (1) CN106536482A (en)
AR (1) AR101222A1 (en)
AU (1) AU2015293578B2 (en)
CA (1) CA2954724A1 (en)
CL (1) CL2017000151A1 (en)
IL (1) IL249560A0 (en)
MA (1) MA40220A (en)
RU (1) RU2016151973A (en)
TW (1) TW201617317A (en)
UY (1) UY36217A (en)
WO (1) WO2016012913A1 (en)
ZA (1) ZA201608598B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018020357A1 (en) 2016-07-25 2018-02-01 Viiv Healthcare Uk Limited Indoline derivatives
WO2018190350A1 (en) 2017-04-10 2018-10-18 三井化学アグロ株式会社 Pyridone compound, and agricultural and horticultural fungicide having this as active component
US10293012B2 (en) 2017-05-04 2019-05-21 Arizona Board Of Regents On Behalf Of Arizona State University Methods of using extracts of melissa officinalis against filoviruses
WO2018208739A1 (en) * 2017-05-08 2018-11-15 Thomas Cahill Pharmaceutical compositions comprising caffeic acid chelates
EP3636636B1 (en) * 2017-06-08 2022-07-06 Mitsui Chemicals Agro, Inc. Pyridone compound and agricultural and horticultural fungicide
EP3828177B1 (en) 2018-07-25 2023-11-29 Mitsui Chemicals Crop & Life Solutions, Inc. Pyridone compound and agricultural and horticultural fungicide having this as active component

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2004002050A1 (en) 2003-08-13 2005-06-03 Pharmacia Corp Sa Organizada B COMPOUNDS DERIVED FROM REPLACED PIRIDINONES; ITS USE IN THE TREATMENT OF AFFECTIONS CAUSED OR EXACTED BY ACTIVITY P38 MAP KINASA AND / OR NON-REGULATED TNF, SUCH AS INFLAMMATIONS, TUMORS, AIDS AND OTHERS.
US7939545B2 (en) * 2006-05-16 2011-05-10 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
US8338441B2 (en) * 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
GB0913636D0 (en) * 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
WO2013002357A1 (en) * 2011-06-30 2013-01-03 塩野義製薬株式会社 Hiv replication inhibitor
EP2757887B1 (en) * 2011-09-22 2017-04-26 VIIV Healthcare UK Limited Pyrrolopyridinone compounds and methods for treating hiv
CA2876370A1 (en) 2012-07-12 2014-01-16 Viiv Healthcare Uk Limited Compounds and methods for treating hiv

Also Published As

Publication number Publication date
RU2016151973A3 (en) 2018-11-09
RU2016151973A (en) 2018-08-22
AU2015293578A1 (en) 2017-01-19
TW201617317A (en) 2016-05-16
KR20170032324A (en) 2017-03-22
ZA201608598B (en) 2019-06-26
JP2017521455A (en) 2017-08-03
WO2016012913A1 (en) 2016-01-28
IL249560A0 (en) 2017-02-28
US9802898B2 (en) 2017-10-31
EP3172189A1 (en) 2017-05-31
CA2954724A1 (en) 2016-01-28
UY36217A (en) 2016-02-29
CN106536482A (en) 2017-03-22
AR101222A1 (en) 2016-11-30
AU2015293578B2 (en) 2017-10-05
US20170217890A1 (en) 2017-08-03
MA40220A (en) 2017-05-31

Similar Documents

Publication Publication Date Title
CY1124215T1 (en) MK2 INHIBITORS AND THEIR USES
MX2022009148A (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES.
CR20170005A (en) INSOINDOLINE DERIVATIVES
EA201891211A1 (en) CXCR2 INHIBITORS
BR112017007636A2 (en) methods for preparing ribosides
PH12018500457A1 (en) New phenoxymethyl derivatives
EA201692203A1 (en) TANK-BINDING KINAZ INHIBITING COMPOUNDS
CL2016002157A1 (en) Anti-cd38 antibodies for the treatment of acute lymphoid leukemia
UY36564A (en) DERIVATIVES OF USEFUL REPLACED NUCLEOSIDS AS ANTINEOPLASTIC AGENTS
MX2018003491A (en) HTT REPRESSORS AND USES OF THESE.
CU20180001A7 (en) SUBSTITUTED OXOPIRIDINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION
EA201791304A1 (en) IZOHINOLINA DERIVATIVES FOR HIV TREATMENT
EA201790266A1 (en) INDOLS FOR USE IN INFECTIONS CAUSED BY THE FLU VIRUS
LT3594238T (en) ANTIBODY COMPOSITIONS FOR THE TREATMENT OF TUMORS
EA201692219A1 (en) METHODS OF OBTAINING ANTI-VIRUS COMPOUNDS
CL2016001973A1 (en) Nucleoside derivatives substituted with 4&#39;-difluoromethyl as inhibitors of influenza arn replication.
EA201691272A1 (en) TETRAHYDROPYRIDOPIRASINES AS GPR6 MODULATORS
CL2017000152A1 (en) Isoindolinone derivatives
EA201790571A1 (en) PYRROPHYRIMIDINES FOR APPLICATION IN INFECTION CAUSED BY THE FLU VIRUS
CL2016003074A1 (en) Compounds derived from 2-oxy-2-phenyl-n-5-pyrrolidin-3-ylamino-1,3,4-thiadiazol-2-ylacetamide, pharmaceutical composition gls1 inhibitors and their use to treat cancer.
CL2017000151A1 (en) Pyridone derivatives
EA201691412A1 (en) HYDROXYFORMAMIDE DERIVATIVES AND THEIR APPLICATION
EA201791530A1 (en) NEW N-ACYLARYL SULPHONAMIDE DERIVATIVES AS AN INHIBITORS AMINOACYL-tRNA SYNTHETASIS
MX2017004655A (en) HYDROXYL PURINE COMPOUNDS AND APPLICATIONS OF THESE.
UA117779C2 (en) POINTS AS GPR6 MODULATORS