CL2017001945A1 - Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide. - Google Patents

Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide.

Info

Publication number
CL2017001945A1
CL2017001945A1 CL2017001945A CL2017001945A CL2017001945A1 CL 2017001945 A1 CL2017001945 A1 CL 2017001945A1 CL 2017001945 A CL2017001945 A CL 2017001945A CL 2017001945 A CL2017001945 A CL 2017001945A CL 2017001945 A1 CL2017001945 A1 CL 2017001945A1
Authority
CL
Chile
Prior art keywords
colloid
molecules
volume
concentration
continuous phase
Prior art date
Application number
CL2017001945A
Other languages
English (en)
Inventor
Silva Francisco Montero
Original Assignee
Univ Tecnica Federico Santa Maria Utfsm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tecnica Federico Santa Maria Utfsm filed Critical Univ Tecnica Federico Santa Maria Utfsm
Priority to CL2017001945A priority Critical patent/CL2017001945A1/es
Priority to US16/622,256 priority patent/US11680885B2/en
Priority to PCT/CL2018/050058 priority patent/WO2019023814A1/es
Publication of CL2017001945A1 publication Critical patent/CL2017001945A1/es
Priority to US18/144,954 priority patent/US20230273107A1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/07—Centrifugal type cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0038—Investigating nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
    • G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
    • G01N2015/047—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis by static multidetectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00495—Centrifuges

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Un método para medir la concentración de moléculas disueltas en la fase continua de un coloide, que comprende las etapas de: a) obtener muestra de prueba mediante mezcla de una cantidad de moléculas con un volumen de coloide; b) obtener muestra control mediante mezcla de una cantidad de moléculas con un volumen de disolución libre de partículas extraído desde una fracción del mismo coloide utilizado en etapa a), tal que el valor de la concentración de moléculas en la mezcla es igual al valor de la concentración de moléculas de la muestra de prueba obtenida en etapa a); c) Someter las muestras obtenidas en etapas a) y b) a proceso para concentrar las partículas de la muestra de prueba obtenida en la etapa a); d) Recuperar un volumen libre de partículas desde la muestra de prueba obtenida en etapa c); e) Recuperar un volumen desde la muestra control obtenida en etapa c); f) Medir al volumen de muestra de prueba recuperado en etapa d) parámetro proporcional a la cantidad de moléculas contenidas en el volumen de muestra; g) Medir al volumen de muestra control recuperado en etapa e) parámetro proporcional a la cantidad de moléculas contenidas en el volumen de muestra; h) Medir la concentración de moléculas en la fase continua del coloide. Un proceso para obtener una composición líquida monofásica desde un volumen de coloide; una composición líquida monofásica extraída desde un coloide; y un Kit para medir la concentración de moléculas solubilizadas en la fase continua de un coloide
CL2017001945A 2017-07-30 2017-07-30 Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide. CL2017001945A1 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CL2017001945A CL2017001945A1 (es) 2017-07-30 2017-07-30 Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide.
US16/622,256 US11680885B2 (en) 2017-07-30 2018-07-27 Method, process, composition and kit for measuring concentration of molecules dissolved in the continuous phase of a colloid
PCT/CL2018/050058 WO2019023814A1 (es) 2017-07-30 2018-07-27 Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide
US18/144,954 US20230273107A1 (en) 2017-07-30 2023-05-09 Method, process, composition and kit for measuring concentration of molecules dissolved in the continuous phase of a colloid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2017001945A CL2017001945A1 (es) 2017-07-30 2017-07-30 Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide.

Publications (1)

Publication Number Publication Date
CL2017001945A1 true CL2017001945A1 (es) 2018-10-19

Family

ID=65232120

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017001945A CL2017001945A1 (es) 2017-07-30 2017-07-30 Método, proceso, composición y kit para medir concentración de moléculas disueltas en la fase continua de un coloide.

Country Status (3)

Country Link
US (2) US11680885B2 (es)
CL (1) CL2017001945A1 (es)
WO (1) WO2019023814A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019227246A1 (es) * 2018-06-01 2019-12-05 Universidad Técnica Federico Santa María Kit y métodos para evaluar las propiedades adsorbentes de la superficie de un material

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7109247B2 (en) 2003-05-30 2006-09-19 3M Innovative Properties Company Stabilized particle dispersions containing nanoparticles
JP2007530397A (ja) 2003-07-16 2007-11-01 ザ ユニヴァーシティー オブ リーディング 複合ナノ粒子
GB201202631D0 (en) 2012-02-16 2012-04-04 Pharmadiagnostics Nv Method of measuring interaction between molecules
CL2018001473A1 (es) * 2018-06-01 2019-10-25 Univ Tecnica Federico Santa Maria Utfsm Kit y métodos para evaluar las propiedades adsorbentes de la superficie de un material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019227246A1 (es) * 2018-06-01 2019-12-05 Universidad Técnica Federico Santa María Kit y métodos para evaluar las propiedades adsorbentes de la superficie de un material

Also Published As

Publication number Publication date
US20200103331A1 (en) 2020-04-02
US20230273107A1 (en) 2023-08-31
WO2019023814A1 (es) 2019-02-07
US11680885B2 (en) 2023-06-20

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