CL2017002313A1 - Alpha-cinnamide compounds and compositions as hdac8 inhibitors - Google Patents
Alpha-cinnamide compounds and compositions as hdac8 inhibitorsInfo
- Publication number
- CL2017002313A1 CL2017002313A1 CL2017002313A CL2017002313A CL2017002313A1 CL 2017002313 A1 CL2017002313 A1 CL 2017002313A1 CL 2017002313 A CL2017002313 A CL 2017002313A CL 2017002313 A CL2017002313 A CL 2017002313A CL 2017002313 A1 CL2017002313 A1 CL 2017002313A1
- Authority
- CL
- Chile
- Prior art keywords
- alpha
- compositions
- hdac8 inhibitors
- inhibitors
- cinnamide compounds
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 101150024367 HDAC8 gene Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102100038715 Histone deacetylase 8 Human genes 0.000 abstract 1
- 101001032118 Homo sapiens Histone deacetylase 8 Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037765 diseases and disorders Diseases 0.000 abstract 1
- 229940121372 histone deacetylase inhibitor Drugs 0.000 abstract 1
- 239000003276 histone deacetylase inhibitor Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
<p>La presente invención se refiere a inhibidores de histona deacetilasas, en particular HDAC8, que son útiles para el tratamiento de cáncer y otras enfermedades y trastornos, así como la síntesis y aplicaciones de dichos inhibidores.</p><p> The present invention relates to histone deacetylase inhibitors, in particular HDAC8, which are useful for the treatment of cancer and other diseases and disorders, as well as the synthesis and applications of said inhibitors. </p>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562132895P | 2015-03-13 | 2015-03-13 | |
| US201562184335P | 2015-06-25 | 2015-06-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2017002313A1 true CL2017002313A1 (en) | 2018-05-18 |
Family
ID=63046387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2017002313A CL2017002313A1 (en) | 2015-03-13 | 2017-09-13 | Alpha-cinnamide compounds and compositions as hdac8 inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| CL (1) | CL2017002313A1 (en) |
-
2017
- 2017-09-13 CL CL2017002313A patent/CL2017002313A1/en unknown
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