CL2018000413A1 - Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos - Google Patents

Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos

Info

Publication number
CL2018000413A1
CL2018000413A1 CL2018000413A CL2018000413A CL2018000413A1 CL 2018000413 A1 CL2018000413 A1 CL 2018000413A1 CL 2018000413 A CL2018000413 A CL 2018000413A CL 2018000413 A CL2018000413 A CL 2018000413A CL 2018000413 A1 CL2018000413 A1 CL 2018000413A1
Authority
CL
Chile
Prior art keywords
products
tissue regeneration
senescent cells
composition
treatment
Prior art date
Application number
CL2018000413A
Other languages
English (en)
Inventor
Martin Funk
Original Assignee
Qrskin Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qrskin Gmbh filed Critical Qrskin Gmbh
Publication of CL2018000413A1 publication Critical patent/CL2018000413A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0076—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

<p>La presente invención se refiere a células senescentes cultivadas in vitro, tales como células epiteliales, queratinocitos y/o fibroblastos, así como a su uso en el tratamiento de regeneración de tejidos, particularmente para el tratamiento de heridas tales como quemaduras o úlceras o el tratamiento de afecciones inflamatorias. Opcionalmente, los productos pueden usarse en combinación con otros fármacos que incluyen agentes antimicrobianos o antidiabéticos.</p>
CL2018000413A 2015-08-21 2018-02-15 Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos CL2018000413A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15182070.1A EP3132809A1 (en) 2015-08-21 2015-08-21 Composition and products comprising senescent cells for use in tissue regeneration

Publications (1)

Publication Number Publication Date
CL2018000413A1 true CL2018000413A1 (es) 2018-06-01

Family

ID=54007554

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018000413A CL2018000413A1 (es) 2015-08-21 2018-02-15 Composición y productos que comprenden células senescentes para su uso en la regeneración de tejidos

Country Status (13)

Country Link
US (1) US10869900B2 (es)
EP (2) EP3132809A1 (es)
CN (1) CN107921169B (es)
BR (1) BR112018003311B1 (es)
CA (1) CA2996235C (es)
CL (1) CL2018000413A1 (es)
CO (1) CO2018001421A2 (es)
DK (1) DK3325025T3 (es)
EC (1) ECSP18012793A (es)
ES (1) ES2781334T3 (es)
MX (1) MX374477B (es)
PE (1) PE20180780A1 (es)
WO (1) WO2017032614A1 (es)

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EP3490476A4 (en) * 2016-08-01 2020-03-25 Drexel University COMPOSITIONS AND METHODS FOR THE TREATMENT OF SKIN DISORDERS
WO2018175630A1 (en) * 2017-03-23 2018-09-27 The Regents Of The University Of California Stimulation of hair growth by senescent cells and senescence associated secretory phenotype
CN107875171A (zh) * 2017-12-08 2018-04-06 深圳市莱利赛生物科技有限公司 一种脐带间充质干细胞药物在促进皮肤伤口愈合中的应用
KR102014467B1 (ko) * 2017-12-14 2019-08-26 (주)녹십자웰빙 아토피성 피부염, 탈모, 상처 또는 피부 주름의 개선용 화장료 조성물 및 약학 조성물
KR20200131301A (ko) * 2018-03-13 2020-11-23 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 세포 노화의 역전을 위한 일시적 세포 재프로그래밍
CN110484509B (zh) * 2019-08-14 2021-07-02 广东医科大学 一种IL1α启动子驱动荧光蛋白表达的永生化SASP细胞模型
IL300592A (en) 2020-02-25 2023-04-01 Amplifica Inc Preparations and methods to stimulate hair growth
CN111297905B (zh) * 2020-03-18 2022-11-04 四川大学华西医院 一种基于皮肤前体细胞的提取物及其制备方法和用途
US11987787B2 (en) 2020-07-22 2024-05-21 AVITA Medical Americas, LLC Devices, methods, and kits for preparing a cell suspension
US20230301977A1 (en) * 2020-09-16 2023-09-28 Agency For Science, Technology And Research Wound healing model
EP4301400A1 (en) * 2021-03-02 2024-01-10 Reverse Bioengineering, Inc. Methods and compositions used to modify chromatin architecture to regulate phenotype in aging and cancer
CN113144221B (zh) * 2021-03-17 2022-11-15 北昊干细胞与再生医学研究院有限公司 外泌体制剂及其制备方法和应用
CN113667632B (zh) * 2021-09-14 2023-10-17 上海艾济生物科技有限公司 细胞培养基添加剂、细胞培养基及细胞体外扩增的方法
JP2025504704A (ja) * 2022-01-31 2025-02-14 センス リサーチ ファウンデーション 老化細胞表面マーカー
EP4531876A4 (en) * 2022-06-01 2026-03-25 Sens Res Foundation TARGETED ELIMINATION OF SENESCENT CELLS BY GAMMA-DELTA T LYMPHOCYTES
WO2024104577A1 (en) 2022-11-16 2024-05-23 Evomedis Gmbh Cells being highly enriched in sasp factors, and composition comprising said cells
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
DE202023002794U1 (de) 2022-12-27 2024-07-15 AVITA Medical Americas, LLC Kassette zur Herstellung einer regenerativen epidermalen Suspension
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge

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ES2149779T3 (es) 1991-11-20 2000-11-16 Innogenetics Nv Lisados derivados de queratinocitos para utilizacion como substancias cicatrizantes.
JPH10509610A (ja) 1994-11-09 1998-09-22 クリ・ハークチ，ワリド 創傷修復用包帯およびそれらの保存法
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
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Also Published As

Publication number Publication date
CO2018001421A2 (es) 2018-04-30
CA2996235A1 (en) 2017-03-02
CN107921169A (zh) 2018-04-17
MX2018001827A (es) 2018-11-09
ECSP18012793A (es) 2018-06-30
PE20180780A1 (es) 2018-05-07
ES2781334T3 (es) 2020-09-01
CN107921169B (zh) 2021-09-07
CA2996235C (en) 2022-10-25
MX374477B (es) 2025-03-06
DK3325025T3 (da) 2020-03-16
EP3325025A1 (en) 2018-05-30
WO2017032614A1 (en) 2017-03-02
EP3325025B1 (en) 2020-01-08
US20180360889A1 (en) 2018-12-20
US10869900B2 (en) 2020-12-22
EP3132809A1 (en) 2017-02-22
BR112018003311A2 (pt) 2018-09-18
BR112018003311B1 (pt) 2022-04-26

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