CL2019000434A1 - Plantas y métodos para aumentar y disminuir la síntesis de cannabinoides. - Google Patents

Plantas y métodos para aumentar y disminuir la síntesis de cannabinoides.

Info

Publication number
CL2019000434A1
CL2019000434A1 CL2019000434A CL2019000434A CL2019000434A1 CL 2019000434 A1 CL2019000434 A1 CL 2019000434A1 CL 2019000434 A CL2019000434 A CL 2019000434A CL 2019000434 A CL2019000434 A CL 2019000434A CL 2019000434 A1 CL2019000434 A1 CL 2019000434A1
Authority
CL
Chile
Prior art keywords
plants
cannabinoids
methods
synthesis
decrease
Prior art date
Application number
CL2019000434A
Other languages
English (en)
Inventor
Robert F Roscow
Original Assignee
Canopy Growth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canopy Growth Corp filed Critical Canopy Growth Corp
Publication of CL2019000434A1 publication Critical patent/CL2019000434A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

ESTA DIVULGACIÓN SE REFIERE A NUEVAS PLANTAS Y MÉTODOS PARA AUMENTAR Y DISMINUIR LA SÍNTESIS DE CANNABINOIDES. LAS PLANTAS DESCRITAS EN ESTE DOCUMENTO COMPRENDEN PROPORCIONES Y CONCENTRACIONES NO NATURALES DE CANNABINOIDES EN PLANTAS DEL GÉNERO CANNABIS. LOS MÉTODOS DESCRITOS EN EL PRESENTE DOCUMENTO COMPRENDEN LA MANIPULACIÓN DE LA RUTA BIOSINTÉTICA DE LOS CANNABINOIDES PARA PRODUCIR PLANTAS DEL GÉNERO CANNABIS CON PROPORCIONES Y CONCENTRACIONES DE CANNABINOIDES NO NATURALES.
CL2019000434A 2016-08-18 2019-02-18 Plantas y métodos para aumentar y disminuir la síntesis de cannabinoides. CL2019000434A1 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662376521P 2016-08-18 2016-08-18
US201662385102P 2016-09-08 2016-09-08
US201662416098P 2016-11-01 2016-11-01
US201662416084P 2016-11-01 2016-11-01
US201662429046P 2016-12-01 2016-12-01
US201662429039P 2016-12-01 2016-12-01
US201662429049P 2016-12-01 2016-12-01

Publications (1)

Publication Number Publication Date
CL2019000434A1 true CL2019000434A1 (es) 2019-05-24

Family

ID=61197425

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2019000434A CL2019000434A1 (es) 2016-08-18 2019-02-18 Plantas y métodos para aumentar y disminuir la síntesis de cannabinoides.

Country Status (12)

Country Link
US (1) US11466283B2 (es)
EP (1) EP3500090A4 (es)
CN (1) CN109890202A (es)
AU (1) AU2017313843A1 (es)
BR (1) BR112019003024A8 (es)
CA (1) CA3033875A1 (es)
CL (1) CL2019000434A1 (es)
CO (1) CO2019002123A2 (es)
MX (1) MX2019001968A (es)
PE (1) PE20190654A1 (es)
WO (1) WO2018035450A1 (es)
ZA (1) ZA201900986B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12168212B2 (en) 2020-04-30 2024-12-17 Hydro Dynamics, Inc. System and method for treatment of plants for synthesis of compounds therefrom

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US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
CA3089994A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
HUE060229T2 (hu) * 2018-02-20 2023-02-28 Mymd Pharmaceuticals Inc Genetikailag módosított cannabis sativa növények és módosított kannabinoid vegyületek a kábítószer-függõség és más rendellenességek kezelésére
CA3105433C (en) * 2018-08-17 2023-07-11 Canbreed Ltd. Cannabis plant cells with reduced delta-9-tetrahydrocannabinol (thc) content
WO2020077153A1 (en) 2018-10-10 2020-04-16 Canopy Holdings, LLC Synthesis of cannabigerol
CN113227353A (zh) * 2018-11-14 2021-08-06 马努斯生物合成股份有限公司 用于产生大麻素的微生物细胞及方法
EP3931330A4 (en) 2019-02-25 2023-03-15 Ginkgo Bioworks, Inc. BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS
SG11202111309RA (en) * 2019-04-11 2021-11-29 Kah Meng Lim Process for producing a genetically modified seed
WO2020227611A1 (en) * 2019-05-09 2020-11-12 New West Genetics Inc. Methods for production of low cost terpenoids, including cannabinoids, and varieties adapted for large-scale planting and density optimization including cannabinoid preservation
CN115942868A (zh) * 2019-05-29 2023-04-07 优良种子有限责任公司 产量提高的大麻植物
WO2021007663A1 (en) * 2019-07-12 2021-01-21 Canopy Growth Corporation Cannabinoid derivatives
CA3148950A1 (en) * 2019-07-30 2021-02-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (A.R.O.), Volcani Center Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
CN112441952B (zh) * 2019-08-28 2021-08-06 析木津生物医药(广州)有限公司 一种大麻二酚-3-磺酸及其制备方法和应用、大麻二酚衍生物
WO2021046154A1 (en) * 2019-09-06 2021-03-11 James Berman Genetic modification of plants
WO2021067645A1 (en) * 2019-10-01 2021-04-08 Intima Bioscience, Inc. Genetically modified plants and methods of making the same
WO2021067640A1 (en) * 2019-10-01 2021-04-08 Intima Bioscience, Inc. Genetically modified plants and methods of making the same
JP2022551066A (ja) * 2019-10-02 2022-12-07 キャノピー グロウス コーポレイション カンナビノイド誘導体
AU2020364533A1 (en) * 2019-10-11 2022-04-21 National University Of Singapore Biosynthesis of cannabinoid precursors using novel aromatic prenyl transferases
EP4055172A4 (en) * 2019-11-04 2024-06-12 Agriculture Victoria Services Pty Ltd METHOD FOR PRODUCING TARGETED GENE EDITING CONSTRUCTS
WO2021240508A1 (en) * 2020-05-27 2021-12-02 Canbreed Ltd Cannabis plants with improved agronomic traits
MX2023000133A (es) * 2020-07-13 2023-02-09 Betterseeds Ltd Cannabis con contenido de cannabinoides alterado.
US20240102034A1 (en) * 2020-07-16 2024-03-28 Daniel Kevin FOWLER Cannabis plant with increased cannabigerolic acid
US20230413750A1 (en) * 2020-10-13 2023-12-28 Canopy Growth Corporation Cannabis plant with increased cannabichromenic acid
US20230265444A1 (en) * 2022-02-24 2023-08-24 Canopy Growth Corporation Gene-editing in cannabis plant
US20250230451A1 (en) * 2022-04-05 2025-07-17 Genkore Inc. Composition comprising gene editing protein for cannabis sativa gene editing, and gene editing method using same

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
WO2011017798A1 (en) * 2009-08-12 2011-02-17 National Research Council Of Canada Aromatic prenyltransferase from cannabis
CA3130705A1 (en) * 2010-04-15 2011-10-20 National Research Council Of Canada Genes and proteins for aromatic polyketide synthesis
US20160177404A1 (en) * 2011-08-18 2016-06-23 Courtagen Life Sciences Inc. Cannabis genomes and uses thereof
US20140245494A1 (en) * 2013-02-25 2014-08-28 Ytzchak Cohen Cannabis plant named erez
US10441617B2 (en) 2013-03-15 2019-10-15 Biotech Institute, Llc Breeding, production, processing and use of medical cannabis
SG11201701245QA (en) * 2014-08-27 2017-03-30 Caribou Biosciences Inc Methods for increasing cas9-mediated engineering efficiency
JP2018519853A (ja) 2015-05-28 2018-07-26 ツイード・インコーポレイテッドＴｗｅｅｄ Ｉｎｃ． Ｔｈｃａ合成酵素の発現を改変したアサ植物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12168212B2 (en) 2020-04-30 2024-12-17 Hydro Dynamics, Inc. System and method for treatment of plants for synthesis of compounds therefrom

Also Published As

Publication number Publication date
ZA201900986B (en) 2019-12-18
MX2019001968A (es) 2019-10-02
CO2019002123A2 (es) 2019-05-31
US20200181631A1 (en) 2020-06-11
EP3500090A1 (en) 2019-06-26
BR112019003024A8 (pt) 2019-09-10
PE20190654A1 (es) 2019-05-08
BR112019003024A2 (pt) 2019-05-14
WO2018035450A1 (en) 2018-02-22
AU2017313843A1 (en) 2019-03-07
US11466283B2 (en) 2022-10-11
CN109890202A (zh) 2019-06-14
EP3500090A4 (en) 2020-01-08
CA3033875A1 (en) 2018-02-22

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