CL2019002174A1 - Composición que comprende capecitabina de liberación inmediata y liberación prolongada. - Google Patents
Composición que comprende capecitabina de liberación inmediata y liberación prolongada.Info
- Publication number
- CL2019002174A1 CL2019002174A1 CL2019002174A CL2019002174A CL2019002174A1 CL 2019002174 A1 CL2019002174 A1 CL 2019002174A1 CL 2019002174 A CL2019002174 A CL 2019002174A CL 2019002174 A CL2019002174 A CL 2019002174A CL 2019002174 A1 CL2019002174 A1 CL 2019002174A1
- Authority
- CL
- Chile
- Prior art keywords
- release
- composition
- capecitabine
- prolonged
- immediate release
- Prior art date
Links
- GAGWJHPBXLXJQN-UORFTKCHSA-N Capecitabine Chemical compound C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1[C@H]1[C@H](O)[C@H](O)[C@@H](C)O1 GAGWJHPBXLXJQN-UORFTKCHSA-N 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000012729 immediate-release (IR) formulation Substances 0.000 title abstract 2
- 230000002035 prolonged effect Effects 0.000 title abstract 2
- GAGWJHPBXLXJQN-UHFFFAOYSA-N Capecitabine Natural products C1=C(F)C(NC(=O)OCCCCC)=NC(=O)N1C1C(O)C(O)C(C)O1 GAGWJHPBXLXJQN-UHFFFAOYSA-N 0.000 title 1
- 229960004117 capecitabine Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA COMPOSICIÓN FARMACÉUTICA DE CAPECITABINA, EN DONDE DICHA COMPOSICIÓN COMPRENDE CAPECITABINA DE LIBERACIÓN INMEDIATA Y CAPECITABINA DE LIBERACIÓN PROLONGADA. ADEMÁS, LA PRESENTE INVENCIÓN DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACIÓN DE DICHA COMPOSICIÓN.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201721004194 | 2017-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019002174A1 true CL2019002174A1 (es) | 2019-11-29 |
Family
ID=63040300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019002174A CL2019002174A1 (es) | 2017-02-06 | 2019-08-02 | Composición que comprende capecitabina de liberación inmediata y liberación prolongada. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20190358253A1 (es) |
| EP (1) | EP3576721A4 (es) |
| JP (1) | JP2020514314A (es) |
| CN (1) | CN110290779A (es) |
| AU (1) | AU2018214291A1 (es) |
| BR (1) | BR112019016028A2 (es) |
| CA (1) | CA3051040A1 (es) |
| CL (1) | CL2019002174A1 (es) |
| IL (1) | IL268137A (es) |
| MX (1) | MX2019009230A (es) |
| PH (1) | PH12019501689A1 (es) |
| RU (1) | RU2019126572A (es) |
| WO (1) | WO2018142359A1 (es) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070122481A1 (en) * | 1998-11-02 | 2007-05-31 | Elan Corporation Plc | Modified Release Compositions Comprising a Fluorocytidine Derivative for the Treatment of Cancer |
| JP2008535920A (ja) * | 2005-04-12 | 2008-09-04 | エラン・ファルマ・インターナショナル・リミテッド | 癌の治療のための、フルオロシチジン誘導体を含む改変放出組成物 |
| MX2011011596A (es) * | 2010-03-31 | 2012-02-01 | Keryx Biopharmaceuticals Inc | Perifosina y capecitabina como un tratamiento combinado para cancer. |
| US20200054659A1 (en) * | 2015-06-13 | 2020-02-20 | Intas Pharmaceuticals Ltd. | Extended release capecitabine capsules |
| CN104997744B (zh) * | 2015-08-04 | 2018-01-23 | 青岛市中心医院 | 一种高稳定性卡培他滨片剂及其制备方法 |
-
2018
- 2018-02-05 AU AU2018214291A patent/AU2018214291A1/en not_active Abandoned
- 2018-02-05 CA CA3051040A patent/CA3051040A1/en not_active Abandoned
- 2018-02-05 CN CN201880009565.2A patent/CN110290779A/zh active Pending
- 2018-02-05 US US16/483,889 patent/US20190358253A1/en not_active Abandoned
- 2018-02-05 WO PCT/IB2018/050703 patent/WO2018142359A1/en not_active Ceased
- 2018-02-05 JP JP2019540096A patent/JP2020514314A/ja active Pending
- 2018-02-05 MX MX2019009230A patent/MX2019009230A/es unknown
- 2018-02-05 BR BR112019016028-0A patent/BR112019016028A2/pt not_active IP Right Cessation
- 2018-02-05 EP EP18747137.0A patent/EP3576721A4/en not_active Withdrawn
- 2018-02-05 RU RU2019126572A patent/RU2019126572A/ru not_active Application Discontinuation
-
2019
- 2019-07-17 IL IL268137A patent/IL268137A/en unknown
- 2019-07-23 PH PH12019501689A patent/PH12019501689A1/en unknown
- 2019-08-02 CL CL2019002174A patent/CL2019002174A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020514314A (ja) | 2020-05-21 |
| EP3576721A1 (en) | 2019-12-11 |
| US20190358253A1 (en) | 2019-11-28 |
| EP3576721A4 (en) | 2020-07-22 |
| MX2019009230A (es) | 2019-09-10 |
| CN110290779A (zh) | 2019-09-27 |
| BR112019016028A2 (pt) | 2020-03-31 |
| RU2019126572A (ru) | 2021-03-09 |
| AU2018214291A1 (en) | 2019-08-01 |
| IL268137A (en) | 2019-09-26 |
| PH12019501689A1 (en) | 2020-03-09 |
| CA3051040A1 (en) | 2018-08-09 |
| WO2018142359A1 (en) | 2018-08-09 |
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